Gene description for XPO6
Gene name exportin 6
Gene symbol XPO6
Other names/aliases EXP6
Species Homo sapiens
 Database cross references - XPO6
ExoCarta ExoCarta_23214
Entrez Gene 23214
HGNC 19733
MIM 608411
UniProt Q96QU8  
 XPO6 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for XPO6
Molecular Function
    protein binding GO:0005515 IPI
    Ran GTPase binding GO:0008536 IEA
    protein transporter activity GO:0008565 IDA
Biological Process
    protein export from nucleus GO:0006611 IDA
Subcellular Localization
    nucleolus GO:0005730 IDA
    cytoplasm GO:0005737 IDA
    nucleoplasm GO:0005654 IDA
    nucleus GO:0005634 IDA
    plasma membrane GO:0005886 IDA
 Experiment description of studies that identified XPO6 in exosomes
Experiment ID 217
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for XPO6
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 PFN1 5216
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
2 BRF2  
Affinity Capture-MS Homo sapiens
3 NUP62 23636
Two-hybrid Homo sapiens
4 ACTB 60
Affinity Capture-MS Homo sapiens
5 ACTA1 58
Affinity Capture-MS Homo sapiens
6 DIAPH1 1729
Affinity Capture-MS Homo sapiens
7 RAN 5901
Affinity Capture-MS Homo sapiens
8 ENAH 55740
Affinity Capture-MS Homo sapiens
9 GSK3B 2932
Affinity Capture-MS Homo sapiens
10 VASP 7408
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which XPO6 is involved
No pathways found

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