Gene description for GLDC
Gene name glycine dehydrogenase (decarboxylating)
Gene symbol GLDC
Other names/aliases GCE
GCSP
HYGN1
Species Homo sapiens
 Database cross references - GLDC
ExoCarta ExoCarta_2731
Entrez Gene 2731
HGNC 4313
MIM 238300
UniProt P23378  
 GLDC identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for GLDC
Molecular Function
    pyridoxal phosphate binding GO:0030170 IEA
    electron carrier activity GO:0009055 TAS
    glycine dehydrogenase (decarboxylating) activity GO:0004375 IEA
    lyase activity GO:0016829 IEA
Biological Process
    oxidation-reduction process GO:0055114 IEA
    glycine catabolic process GO:0006546 IEA
Subcellular Localization
    mitochondrion GO:0005739 IEA
 Experiment description of studies that identified GLDC in exosomes
1
Experiment ID 126
ISEV standards
EV Biophysical techniques
GAPDH
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for GLDC
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 GLDC 2731
Co-purification Homo sapiens
Co-purification Homo sapiens
View the network image/svg+xml
 Pathways in which GLDC is involved
No pathways found





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