Experiment description of studies that identified RHBDD1 in sEVs

1 Experiment ID 235 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" Journal name Carcinogenesis Publication year 2015 Sample Hepatocellular carcinoma cells Sample name HKCI-8 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RT-PCR RNA Sequencing

Protein-protein interactions for RHBDD1

Protein Interactor ExoCarta ID Identification method PubMed Species 1 OR2M7   Affinity Capture-MS Homo sapiens 2 SEC22B 9554 Two-hybrid Homo sapiens 3 A1BG 1 Affinity Capture-MS Homo sapiens 4 IGHG3 3502 Affinity Capture-MS Homo sapiens 5 IGLC2 3538 Affinity Capture-MS Homo sapiens 6 SERPINB4 6318 Affinity Capture-MS Homo sapiens 7 CEACAM8 1088 Affinity Capture-MS Homo sapiens 8 CHRNA4   Affinity Capture-MS Homo sapiens 9 RXFP1   Affinity Capture-MS Homo sapiens 10 AZU1 566 Affinity Capture-MS Homo sapiens 11 OR10H2   Affinity Capture-MS Homo sapiens 12 PQLC1   Two-hybrid Homo sapiens 13 IVL 3713 Affinity Capture-MS Homo sapiens 14 PCDHGB5 56101 Affinity Capture-MS Homo sapiens 15 NRSN1   Affinity Capture-MS Homo sapiens 16 ABCB5   Affinity Capture-MS Homo sapiens 17 TPTE2   Affinity Capture-MS Homo sapiens 18 MYO1F 4542 Affinity Capture-MS Homo sapiens 19 GC 2638 Affinity Capture-MS Homo sapiens 20 FBXO25   Biochemical Activity Homo sapiens 21 HK3   Affinity Capture-MS Homo sapiens 22 ARSE 415 Affinity Capture-MS Homo sapiens 23 IGHM 3507 Affinity Capture-MS Homo sapiens 24 BSCL2   Affinity Capture-MS Homo sapiens 25 OR6M1   Affinity Capture-MS Homo sapiens 26 ITIH2 3698 Affinity Capture-MS Homo sapiens 27 AHSG 197 Affinity Capture-MS Homo sapiens 28 PLG 5340 Affinity Capture-MS Homo sapiens 29 NCF1   Affinity Capture-MS Homo sapiens 30 S100P 6286 Affinity Capture-MS Homo sapiens 31 KDELR1 10945 Affinity Capture-MS Homo sapiens 32 HPX 3263 Affinity Capture-MS Homo sapiens 33 GABRG2   Affinity Capture-MS Homo sapiens 34 PIGN 23556 Affinity Capture-MS Homo sapiens 35 ITIH1 3697 Affinity Capture-MS Homo sapiens 36 GSDMA 284110 Affinity Capture-MS Homo sapiens 37 RNF5   Affinity Capture-MS Homo sapiens Two-hybrid Homo sapiens 38 CTLA4   Affinity Capture-MS Homo sapiens 39 ORM1 5004 Affinity Capture-MS Homo sapiens 40 C3 718 Affinity Capture-MS Homo sapiens 41 FAM8A1 51439 Affinity Capture-MS Homo sapiens 42 ACPP 55 Affinity Capture-MS Homo sapiens 43 S100A9 6280 Affinity Capture-MS Homo sapiens 44 YIPF3 25844 Affinity Capture-MS Homo sapiens 45 TMED9 54732 Affinity Capture-MS Homo sapiens 46 C1QC 714 Affinity Capture-MS Homo sapiens 47 BTNL8   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 48 CHI3L1 1116 Affinity Capture-MS Homo sapiens 49 CPA4 51200 Affinity Capture-MS Homo sapiens 50 CCDC47 57003 Affinity Capture-MS Homo sapiens 51 SERPINA1 5265 Affinity Capture-MS Homo sapiens 52 PRTN3 5657 Affinity Capture-MS Homo sapiens 53 TMEM63C   Affinity Capture-MS Homo sapiens 54 TMEM136   Affinity Capture-MS Homo sapiens 55 ITGAM 3684 Affinity Capture-MS Homo sapiens 56 GCA 25801 Affinity Capture-MS Homo sapiens 57 RNF185   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 58 CBR1 873 Affinity Capture-MS Homo sapiens 59 VTN 7448 Affinity Capture-MS Homo sapiens 60 HTR3C   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 61 MANSC1 54682 Affinity Capture-MS Homo sapiens 62 POF1B 79983 Affinity Capture-MS Homo sapiens 63 HRG 3273 Affinity Capture-MS Homo sapiens 64 OR5H1   Affinity Capture-MS Homo sapiens 65 PLBD1 79887 Affinity Capture-MS Homo sapiens 66 IGHA2 3494 Affinity Capture-MS Homo sapiens 67 FGA 2243 Affinity Capture-MS Homo sapiens 68 STOM 2040 Affinity Capture-MS Homo sapiens 69 OR4N2   Affinity Capture-MS Homo sapiens 70 A2M 2 Affinity Capture-MS Homo sapiens 71 ORM2   Affinity Capture-MS Homo sapiens 72 PLEKHB2 55041 Two-hybrid Homo sapiens 73 OR2W3   Affinity Capture-MS Homo sapiens 74 CTSG 1511 Affinity Capture-MS Homo sapiens 75 FGG 2266 Affinity Capture-MS Homo sapiens 76 VCP 7415 Co-crystal Structure Homo sapiens Reconstituted Complex Homo sapiens Reconstituted Complex Homo sapiens 77 KCNA6   Affinity Capture-MS Homo sapiens 78 S100A8 6279 Affinity Capture-MS Homo sapiens 79 TTR 7276 Affinity Capture-MS Homo sapiens 80 TACSTD2 4070 Affinity Capture-MS Homo sapiens 81 ELANE 1991 Affinity Capture-MS Homo sapiens 82 ALB 213 Affinity Capture-MS Homo sapiens 83 SERPINB7 8710 Affinity Capture-MS Homo sapiens 84 ITGB2 3689 Affinity Capture-MS Homo sapiens 85 SERPINA3 12 Affinity Capture-MS Homo sapiens 86 GYPC 2995 Two-hybrid Homo sapiens 87 IGKC 3514 Affinity Capture-MS Homo sapiens 88 COX4I1 1327 Affinity Capture-MS Homo sapiens 89 CALML3 810 Affinity Capture-MS Homo sapiens 90 C9 735 Affinity Capture-MS Homo sapiens 91 FAM189B   Affinity Capture-MS Homo sapiens 92 MPO 4353 Affinity Capture-MS Homo sapiens 93 SERPINB3 6317 Affinity Capture-MS Homo sapiens 94 MMP8   Affinity Capture-MS Homo sapiens 95 TYMP 1890 Affinity Capture-MS Homo sapiens 96 TMIE   Two-hybrid Homo sapiens 97 SERPIND1 3053 Affinity Capture-MS Homo sapiens 98 APOB 338 Affinity Capture-MS Homo sapiens 99 CARTPT   Affinity Capture-MS Homo sapiens 100 S100A7 6278 Affinity Capture-MS Homo sapiens 101 CP 1356 Affinity Capture-MS Homo sapiens 102 TMEM42   Two-hybrid Homo sapiens 103 S100A7A 338324 Affinity Capture-MS Homo sapiens 104 PI4K2A 55361 Affinity Capture-MS Homo sapiens 105 CREB3L1   Two-hybrid Homo sapiens 106 FN1 2335 Affinity Capture-MS Homo sapiens 107 APCS 325 Affinity Capture-MS Homo sapiens 108 FUT3 2525 Affinity Capture-MS Homo sapiens 109 NOX1   Affinity Capture-MS Homo sapiens 110 TMEM86B   Two-hybrid Homo sapiens 111 CHRNB4   Affinity Capture-MS Homo sapiens 112 PCDH10 57575 Affinity Capture-MS Homo sapiens 113 CMTM5   Two-hybrid Homo sapiens 114 IGHG4 3503 Affinity Capture-MS Homo sapiens 115 LGALS7B 653499 Affinity Capture-MS Homo sapiens 116 KNG1 3827 Affinity Capture-MS Homo sapiens 117 IGHG1 3500 Affinity Capture-MS Homo sapiens 118 C8G 733 Affinity Capture-MS Homo sapiens 119 MMP9 4318 Affinity Capture-MS Homo sapiens 120 SERPING1 710 Affinity Capture-MS Homo sapiens 121 SLC17A8   Affinity Capture-MS Homo sapiens 122 ITIH4 3700 Affinity Capture-MS Homo sapiens 123 KCNA5   Affinity Capture-MS Homo sapiens 124 LCN2 3934 Affinity Capture-MS Homo sapiens 125 PEF1 553115 Affinity Capture-MS Homo sapiens 126 KCNA2   Affinity Capture-MS Homo sapiens 127 A2ML1 144568 Affinity Capture-MS Homo sapiens 128 LDLRAD1   Affinity Capture-MS Homo sapiens 129 MNDA 4332 Affinity Capture-MS Homo sapiens 130 IGLL5 100423062 Affinity Capture-MS Homo sapiens 131 CFH 3075 Affinity Capture-MS Homo sapiens 132 KCNC4   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 133 EDEM1   Affinity Capture-MS Homo sapiens 134 FGB 2244 Affinity Capture-MS Homo sapiens 135 NSDHL 50814 Two-hybrid Homo sapiens 136 IGHG2 3501 Affinity Capture-MS Homo sapiens 137 OR2G6   Affinity Capture-MS Homo sapiens 138 OLFM4 10562 Affinity Capture-MS Homo sapiens 139 TF 7018 Affinity Capture-MS Homo sapiens 140 TGM3 7053 Affinity Capture-MS Homo sapiens 141 CALML5 51806 Affinity Capture-MS Homo sapiens 142 GM2A 2760 Affinity Capture-MS Homo sapiens 143 TGM1 7051 Affinity Capture-MS Homo sapiens 144 BPI 671 Affinity Capture-MS Homo sapiens 145 PLA2G4D   Affinity Capture-MS Homo sapiens 146 TMC4   Affinity Capture-MS Homo sapiens 147 FAM189A2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 148 MARCH4   Affinity Capture-MS Homo sapiens 149 TMEM31   Affinity Capture-MS Homo sapiens 150 LTF 4057 Affinity Capture-MS Homo sapiens 151 VIM 7431 Affinity Capture-MS Homo sapiens 152 CHRNB1   Affinity Capture-MS Homo sapiens 153 LCP1 3936 Affinity Capture-MS Homo sapiens 154 B3GNT8   Affinity Capture-MS Homo sapiens 155 MCOLN2   Affinity Capture-MS Homo sapiens 156 CTSH 1512 Affinity Capture-MS Homo sapiens View the network

Pathways in which RHBDD1 is involved

No pathways found