Gene description for EPS15
Gene name epidermal growth factor receptor pathway substrate 15
Gene symbol EPS15
Other names/aliases AF-1P
AF1P
MLLT5
Species Homo sapiens
 Database cross references - EPS15
ExoCarta ExoCarta_2060
Vesiclepedia VP_2060
Entrez Gene 2060
HGNC 3419
MIM 600051
UniProt P42566  
 EPS15 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Platelets 25332113    
Platelets 25332113    
Platelets 25332113    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
Thymus 23844026    
 Gene ontology annotations for EPS15
Molecular Function
    calcium ion binding GO:0005509 IEA
    protein binding GO:0005515 IPI
    SH3 domain binding GO:0017124 IEA
    polyubiquitin modification-dependent protein binding GO:0031593 IDA
    cadherin binding GO:0045296 HDA
Biological Process
    positive regulation of receptor recycling GO:0001921 IEA
    Golgi to endosome transport GO:0006895 IMP
    endocytosis GO:0006897 IBA
    protein transport GO:0015031 IEA
    vesicle organization GO:0016050 TAS
    endosomal transport GO:0016197 IBA
    receptor-mediated endocytosis of virus by host cell GO:0019065 IMP
    endocytic recycling GO:0032456 IC
    regulation of cell population proliferation GO:0042127 IEA
    symbiont entry into host cell GO:0046718 IMP
    clathrin coat assembly GO:0048268 IDA
    postsynaptic neurotransmitter receptor internalization GO:0098884 IEA
Subcellular Localization
    cytoplasm GO:0005737 IBA
    cytosol GO:0005829 IDA
    cytosol GO:0005829 TAS
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 IDA
    clathrin-coated pit GO:0005905 TAS
    basal plasma membrane GO:0009925 IEA
    membrane GO:0016020 HDA
    aggresome GO:0016235 IDA
    apical plasma membrane GO:0016324 IEA
    clathrin coat of coated pit GO:0030132 IBA
    early endosome membrane GO:0031901 IEA
    intracellular membrane-bounded organelle GO:0043231 IDA
    postsynaptic endocytic zone GO:0098843 IEA
    glutamatergic synapse GO:0098978 IEA
 Experiment description of studies that identified EPS15 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
6
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
7
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 231
MISEV standards
✘ Biophysical techniques
✔
Alix|CD63|CD9
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Western blotting
Mass spectrometry
9
Experiment ID 232
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
10
Experiment ID 233
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
11
Experiment ID 834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
13
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for EPS15
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 UBE2H 7328
Biochemical Activity Homo sapiens
2 AP2S1 1175
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 KRT37 8688
Affinity Capture-MS Homo sapiens
4 KRT73 319101
Affinity Capture-MS Homo sapiens
5 OXCT1 5019
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 AP2B1 163
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 PPP1CB 5500
Affinity Capture-MS Homo sapiens
8 CCT3 7203
Affinity Capture-MS Homo sapiens
9 KRT1 3848
Affinity Capture-MS Homo sapiens
10 OCLN 100506658
Affinity Capture-Western Homo sapiens
11 EPN3 55040
Affinity Capture-Western Homo sapiens
12 SYCE1  
Affinity Capture-MS Homo sapiens
13 GJA1 2697
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-Western Homo sapiens
14 SH3BP4 23677
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
15 KRT6A 3853
Affinity Capture-MS Homo sapiens
16 KRT17 3872
Affinity Capture-MS Homo sapiens
17 CD4 920
Affinity Capture-Western Homo sapiens
18 Calml3  
Affinity Capture-MS Mus musculus
19 Numb  
Affinity Capture-MS Mus musculus
Affinity Capture-Western Mus musculus
Co-localization Mus musculus
20 GAK 2580
Affinity Capture-MS Homo sapiens
21 LIMA1 51474
Affinity Capture-MS Homo sapiens
22 HSPA1L 3305
Affinity Capture-MS Homo sapiens
23 EPS15 2060
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
24 MAP4 4134
Affinity Capture-MS Homo sapiens
25 C9orf78 51759
Affinity Capture-MS Homo sapiens
26 CORO7 79585
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
27 KRT4 3851
Affinity Capture-MS Homo sapiens
28 UBC 7316
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
29 KRT82 3888
Affinity Capture-MS Homo sapiens
30 ARHGAP18 93663
Affinity Capture-MS Homo sapiens
31 Actb 11461
Affinity Capture-MS Mus musculus
32 CLTB 1212
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
33 REPS2  
Affinity Capture-Western Homo sapiens
Far Western Homo sapiens
34 RNPS1 10921
Affinity Capture-MS Homo sapiens
35 DYRK1A 1859
Affinity Capture-MS Homo sapiens
36 TGFB1 7040
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
37 AP2A1 160
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
38 HGS 9146
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
39 IQGAP1 8826
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 AP1G1 164
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
41 MAPK14 1432
Biochemical Activity Homo sapiens
42 UBQLN1 29979
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
43 HIST4H4 121504
Affinity Capture-MS Homo sapiens
44 EPS15L1 58513
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
45 Tpm1 22003
Affinity Capture-MS Mus musculus
46 INO80E  
Affinity Capture-MS Homo sapiens
47 ITGA4 3676
Affinity Capture-MS Homo sapiens
48 VCAM1 7412
Affinity Capture-MS Homo sapiens
49 KRT83  
Affinity Capture-MS Homo sapiens
50 GTSE1 51512
Affinity Capture-MS Homo sapiens
51 Sec24c  
Affinity Capture-MS Mus musculus
52 DVL2 1856
Affinity Capture-MS Homo sapiens
53 NEDD4 4734
Biochemical Activity Homo sapiens
54 RNF26  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
55 Lima1  
Affinity Capture-MS Mus musculus
56 MACC1 346389
Affinity Capture-MS Homo sapiens
57 RNF11 26994
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
58 HSPA8 3312
Affinity Capture-MS Homo sapiens
59 C15orf59  
Affinity Capture-MS Homo sapiens
60 TFAP2A  
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
61 PFN1 5216
Cross-Linking-MS (XL-MS) Homo sapiens
62 AURKA 6790
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
63 CCDC172  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
64 STAM2 10254
Affinity Capture-Western Homo sapiens
65 KRT34  
Affinity Capture-MS Homo sapiens
66 MIB1 57534
Proximity Label-MS Homo sapiens
67 KRT5 3852
Affinity Capture-MS Homo sapiens
68 AGFG1 3267
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Phenotypic Enhancement Homo sapiens
Reconstituted Complex Homo sapiens
69 SPOPL  
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
70 PARK2  
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
71 SNAP91 9892
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
72 OPTN 10133
Two-hybrid Homo sapiens
73 NONO 4841
Affinity Capture-MS Homo sapiens
74 MAPRE1 22919
Affinity Capture-MS Homo sapiens
75 DNAJC5 80331
Proximity Label-MS Homo sapiens
76 KRT35 3886
Affinity Capture-MS Homo sapiens
77 LAPTM5 7805
Two-hybrid Homo sapiens
78 USP8 9101
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
79 NECAP2 55707
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
80 CDH1 999
Proximity Label-MS Homo sapiens
81 TUBB 203068
Affinity Capture-MS Homo sapiens
82 NUMB 8650
Affinity Capture-Western Homo sapiens
83 MYH9 4627
Affinity Capture-MS Homo sapiens
84 NTRK1 4914
Affinity Capture-MS Homo sapiens
85 CRKL 1399
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
86 CRK 1398
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Far Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
87 SYNC  
Affinity Capture-MS Homo sapiens
88 KRT9 3857
Affinity Capture-MS Homo sapiens
89 KRT75 9119
Affinity Capture-MS Homo sapiens
90 AP1B1 162
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
91 KRT14 3861
Affinity Capture-MS Homo sapiens
92 BMP2K 55589
Affinity Capture-MS Homo sapiens
93 RPA4  
Proximity Label-MS Homo sapiens
94 ACTB 60
Affinity Capture-MS Homo sapiens
95 RUNDC3A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
96 KRT2 3849
Affinity Capture-MS Homo sapiens
97 UBE2D3 7323
Biochemical Activity Homo sapiens
98 DNM2 1785
Affinity Capture-Western Homo sapiens
99 Synj1 85238
Far Western Rattus norvegicus
Reconstituted Complex Rattus norvegicus
100 PICALM 8301
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
101 UBE2D1 7321
Biochemical Activity Homo sapiens
102 KRT79 338785
Affinity Capture-MS Homo sapiens
103 DBN1 1627
Affinity Capture-MS Homo sapiens
104 FCHO1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
105 ANLN 54443
Affinity Capture-MS Homo sapiens
106 KRT85  
Affinity Capture-MS Homo sapiens
107 RUFY4  
Affinity Capture-MS Homo sapiens
108 STON2 85439
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Co-crystal Structure Homo sapiens
109 HSPA5 3309
Affinity Capture-MS Homo sapiens
110 KRT3 3850
Affinity Capture-MS Homo sapiens
111 CLINT1 9685
Reconstituted Complex Homo sapiens
112 Myh9 17886
Affinity Capture-MS Mus musculus
113 Zwint  
Affinity Capture-MS Mus musculus
114 KRT33B 3884
Affinity Capture-MS Homo sapiens
115 MCCC2 64087
Affinity Capture-MS Homo sapiens
116 XPO1 7514
Affinity Capture-MS Homo sapiens
117 PCCB 5096
Affinity Capture-MS Homo sapiens
118 KRT86  
Affinity Capture-MS Homo sapiens
119 SCAMP1 9522
Two-hybrid Homo sapiens
120 KRT32  
Affinity Capture-MS Homo sapiens
121 UBQLN2 29978
Affinity Capture-Western Homo sapiens
122 KRTAP9-3  
Affinity Capture-MS Homo sapiens
123 MTNR1A  
Two-hybrid Homo sapiens
124 EGFR 1956
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
125 MYO19  
Affinity Capture-MS Homo sapiens
126 SLC25A41  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
127 FN1 2335
Affinity Capture-MS Homo sapiens
128 AP2M1 1173
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
129 UBE2D2 7322
Biochemical Activity Homo sapiens
130 SYNPO 11346
Affinity Capture-MS Homo sapiens
131 RARRES1 5918
Affinity Capture-MS Homo sapiens
132 Flnb 286940
Affinity Capture-MS Mus musculus
133 FCHO2 115548
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
134 UBE2E1  
Biochemical Activity Homo sapiens
135 EPN1 29924
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Far Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
136 AP2A2 161
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
137 RAB11FIP2  
Affinity Capture-Western Homo sapiens
138 HSPA1A 3303
Cross-Linking-MS (XL-MS) Homo sapiens
139 PTPN23 25930
Proximity Label-MS Homo sapiens
140 SGIP1  
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Co-crystal Structure Homo sapiens
141 CLTC 1213
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
142 AGFG2  
Co-fractionation Homo sapiens
Phenotypic Enhancement Homo sapiens
143 STAMBPL1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
144 HSPA9 3313
Affinity Capture-MS Homo sapiens
145 KRT16 3868
Affinity Capture-MS Homo sapiens
146 DNAJC6  
Affinity Capture-MS Homo sapiens
147 ACBD5 91452
Proximity Label-MS Homo sapiens
148 Dab2 13132
Affinity Capture-Western Mus musculus
Reconstituted Complex Mus musculus
149 RAD23A 5886
Affinity Capture-MS Homo sapiens
150 PDLIM7 9260
Affinity Capture-MS Homo sapiens
151 POLR2J3  
Affinity Capture-MS Homo sapiens
152 TRAF2 7186
Affinity Capture-MS Homo sapiens
153 KIF14 9928
Affinity Capture-MS Homo sapiens
154 ITSN1 6453
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
155 GRB2 2885
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Far Western Homo sapiens
Affinity Capture-Western Homo sapiens
156 KRT36 8689
Affinity Capture-MS Homo sapiens
157 LSR 51599
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
158 Fcho2  
Affinity Capture-MS Mus musculus
Affinity Capture-Western Mus musculus
159 KRT10 3858
Affinity Capture-MS Homo sapiens
160 Myo1c 17913
Affinity Capture-MS Mus musculus
161 HNRNPA2B1 3181
Affinity Capture-MS Homo sapiens
162 CAPZA2 830
Affinity Capture-MS Homo sapiens
163 VSIG8  
Affinity Capture-MS Homo sapiens
164 ABL1 25
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
165 NECAP1 25977
Affinity Capture-MS Homo sapiens
166 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
167 RABL6 55684
Co-fractionation Homo sapiens
168 SLC6A3  
Affinity Capture-Western Homo sapiens
169 DDX58 23586
Affinity Capture-RNA Homo sapiens
170 Myh10 77579
Affinity Capture-MS Mus musculus
171 SPC25 57405
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
172 ITSN2 50618
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
173 VPRBP 9730
Affinity Capture-MS Homo sapiens
174 KRT38 8687
Affinity Capture-MS Homo sapiens
175 FLNA 2316
Affinity Capture-MS Homo sapiens
176 ZCCHC10  
Affinity Capture-MS Homo sapiens
177 CLTA 1211
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
178 PRDX1 5052
Affinity Capture-MS Homo sapiens
179 SPG20 23111
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
180 Flot1 14251
Affinity Capture-MS Mus musculus
181 EPHA2 1969
Affinity Capture-Western Homo sapiens
182 MYO6 4646
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
183 RPA3 6119
Proximity Label-MS Homo sapiens
184 NAGPA 51172
Reconstituted Complex Homo sapiens
185 HSPA1B 3304
Affinity Capture-MS Homo sapiens
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Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here