Gene description for CTBP2
Gene name C-terminal binding protein 2
Gene symbol CTBP2
Other names/aliases -
Species Homo sapiens
 Database cross references - CTBP2
ExoCarta ExoCarta_1488
Vesiclepedia VP_1488
Entrez Gene 1488
HGNC 2495
MIM 602619
UniProt P56545  
 CTBP2 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Colorectal cancer cells 34887515    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Mesenchymal stem cells Unpublished / Not applicable
Mesenchymal stem cells 36408942    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
 Gene ontology annotations for CTBP2
Molecular Function
    transcription coregulator binding GO:0001221 IBA
    transcription corepressor binding GO:0001222 IPI
    transcription coactivator activity GO:0003713 IBA
    transcription corepressor activity GO:0003714 IBA
    transcription corepressor activity GO:0003714 TAS
    protein binding GO:0005515 IPI
    oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0016616 IEA
    protein kinase binding GO:0019901 IPI
    identical protein binding GO:0042802 IPI
    protein-containing complex binding GO:0044877 IPI
    NAD binding GO:0051287 IEA
    DNA-binding transcription factor binding GO:0140297 IBA
Biological Process
    negative regulation of transcription by RNA polymerase II GO:0000122 TAS
    regulation of transcription by RNA polymerase II GO:0006357 IBA
    negative regulation of cell population proliferation GO:0008285 TAS
    viral genome replication GO:0019079 TAS
    negative regulation of DNA-templated transcription GO:0045892 ISS
    positive regulation of transcription by RNA polymerase II GO:0045944 IMP
    positive regulation of retinoic acid receptor signaling pathway GO:0048386 IMP
    white fat cell differentiation GO:0050872 ISS
Subcellular Localization
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IDA
    nucleus GO:0005634 ISS
    transcription repressor complex GO:0017053 ISS
    synapse GO:0045202 IEA
 Experiment description of studies that identified CTBP2 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
6
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
7
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
8
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
9
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
10
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
11
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
12
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
13
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
14
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
15
Experiment ID 126
MISEV standards
✘ Biophysical techniques
✔
GAPDH
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
16
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
17
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
18
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
19
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
20
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for CTBP2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 C15orf39  
Two-hybrid Homo sapiens
2 HIST2H2BE 8349
Affinity Capture-MS Homo sapiens
3 ENKD1  
Two-hybrid Homo sapiens
4 GATAD2B 57459
Affinity Capture-MS Homo sapiens
5 SPRTN  
Affinity Capture-MS Homo sapiens
6 HDAC2 3066
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
7 CCNH  
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
8 QARS 5859
Two-hybrid Homo sapiens
9 MYLK4  
Affinity Capture-MS Homo sapiens
10 CTPS2 56474
Two-hybrid Homo sapiens
11 CTBP2 1488
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
12 AES 166
Two-hybrid Homo sapiens
13 RPA2 6118
Proximity Label-MS Homo sapiens
14 ZNF750  
Two-hybrid Homo sapiens
15 GPALPP1  
Affinity Capture-MS Homo sapiens
16 IGFBP1  
Affinity Capture-MS Homo sapiens
17 UBC 7316
Two-hybrid Homo sapiens
18 CSNK2A1 1457
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 CACNB4  
Two-hybrid Homo sapiens
20 VRTN  
Two-hybrid Homo sapiens
21 SOX2  
Affinity Capture-MS Homo sapiens
22 KCNIP3  
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
23 DNAJB6 10049
Affinity Capture-MS Homo sapiens
24 THAP11 57215
Affinity Capture-MS Homo sapiens
25 KLF8  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
26 HOXA5  
Two-hybrid Homo sapiens
27 HELZ 9931
Affinity Capture-MS Homo sapiens
28 XIAP  
Affinity Capture-Western Homo sapiens
29 TIMMDC1  
Affinity Capture-MS Homo sapiens
30 NOL4L  
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
31 ZNF512B  
Two-hybrid Homo sapiens
32 PROX1  
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
33 ZBTB18  
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
34 MKI67  
Co-fractionation Homo sapiens
35 APP 351
Reconstituted Complex Homo sapiens
36 TULP3 7289
Affinity Capture-MS Homo sapiens
37 CATSPER1  
Two-hybrid Homo sapiens
38 BIRC3 330
Affinity Capture-Western Homo sapiens
PCA Homo sapiens
39 ZNF219  
Affinity Capture-MS Homo sapiens
40 RBBP8NL  
Two-hybrid Homo sapiens
41 MRPS7 51081
Affinity Capture-MS Homo sapiens
42 WIZ 58525
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
43 CTPS1 1503
Co-fractionation Homo sapiens
44 SNTG1  
Affinity Capture-MS Homo sapiens
45 AKTIP  
Two-hybrid Homo sapiens
46 FOXP2 93986
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
47 CSNK2B 1460
Affinity Capture-MS Homo sapiens
48 FUNDC1  
Two-hybrid Homo sapiens
49 LMO4  
Two-hybrid Homo sapiens
50 DVL2 1856
Two-hybrid Homo sapiens
51 ZFPM2  
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
52 HSPA8 3312
Affinity Capture-MS Homo sapiens
53 DYRK1B  
Affinity Capture-MS Homo sapiens
54 PLCB1 23236
Two-hybrid Homo sapiens
55 CACNB3  
Two-hybrid Homo sapiens
56 DDX19B 11269
Co-fractionation Homo sapiens
57 RB1 5925
Negative Genetic Homo sapiens
58 ZNF217 7764
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
59 TRIML2  
Two-hybrid Homo sapiens
60 BAZ2B  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
61 FHL3 2275
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
62 DMRTB1  
Two-hybrid Homo sapiens
63 CAPN7 23473
Two-hybrid Homo sapiens
64 FOXI2  
Affinity Capture-MS Homo sapiens
65 PARK2  
Affinity Capture-MS Homo sapiens
66 CTBP1 1487
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
67 GLIS2  
Two-hybrid Homo sapiens
68 HIC1  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
69 CSTF2 1478
Two-hybrid Homo sapiens
70 TEAD3  
Two-hybrid Homo sapiens
71 BCAS3 54828
Two-hybrid Homo sapiens
72 HOXC5  
Two-hybrid Homo sapiens
73 UBE2I 7329
Two-hybrid Homo sapiens
74 EP300 2033
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
75 MKRN2 23609
Affinity Capture-RNA Homo sapiens
76 NELFE 7936
Affinity Capture-MS Homo sapiens
77 MTMR7  
Affinity Capture-MS Homo sapiens
78 DTNB 1838
Two-hybrid Homo sapiens
79 CCR5 1234
Two-hybrid Homo sapiens
80 ZEB2  
Affinity Capture-MS Homo sapiens
81 HEMGN  
Two-hybrid Homo sapiens
82 PRDM16 63976
Affinity Capture-MS Homo sapiens
83 CBX6  
Affinity Capture-MS Homo sapiens
84 CTSB 1508
Co-fractionation Homo sapiens
85 CACNB2  
Two-hybrid Homo sapiens
86 CREBBP  
Affinity Capture-MS Homo sapiens
87 MBD3 53615
Affinity Capture-MS Homo sapiens
88 KLF12  
Proximity Label-MS Homo sapiens
89 ACTG1 71
Two-hybrid Homo sapiens
90 FOXS1  
Affinity Capture-MS Homo sapiens
91 VSX1  
Affinity Capture-MS Homo sapiens
92 CKMT1B 1159
Affinity Capture-MS Homo sapiens
93 FOXF2  
Affinity Capture-MS Homo sapiens
94 FLI1  
Two-hybrid Homo sapiens
95 BIRC2  
Affinity Capture-Western Homo sapiens
PCA Homo sapiens
96 ZSCAN4  
Two-hybrid Homo sapiens
97 MAP7 9053
Affinity Capture-MS Homo sapiens
98 DCAF7 10238
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
99 SOX6  
Two-hybrid Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-Western Homo sapiens
100 EGLN3  
Two-hybrid Homo sapiens
101 EIF4G1 1981
Two-hybrid Homo sapiens
102 ECT2 1894
Affinity Capture-MS Homo sapiens
103 HOXB5  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
104 CCDC120  
Two-hybrid Homo sapiens
105 CTNNB1 1499
Affinity Capture-MS Homo sapiens
106 RASGRF2  
Affinity Capture-MS Homo sapiens
107 SLC35F2 54733
Affinity Capture-MS Homo sapiens
108 CUL3 8452
Affinity Capture-MS Homo sapiens
109 SYT6  
Affinity Capture-MS Homo sapiens
110 WIF1 11197
Affinity Capture-MS Homo sapiens
111 EGFR 1956
Affinity Capture-MS Homo sapiens
112 BCL3  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
113 IKZF1  
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
114 RBBP4 5928
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
115 HIST3H3 8290
Biochemical Activity Homo sapiens
116 KIAA0430  
Affinity Capture-MS Homo sapiens
117 CDC25C  
Affinity Capture-MS Homo sapiens
118 RBM26 64062
Affinity Capture-MS Homo sapiens
119 PCBP1 5093
Affinity Capture-MS Homo sapiens
120 SERBP1 26135
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
121 FOXP1 27086
Affinity Capture-MS Homo sapiens
122 SDCBP 6386
Two-hybrid Homo sapiens
123 EHMT1  
Affinity Capture-Western Homo sapiens
124 CSNK2A2 1459
Affinity Capture-MS Homo sapiens
125 MSRB3 253827
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
126 EHMT2 10919
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
127 KDM1A 23028
Affinity Capture-MS Homo sapiens
128 DUSP21  
Two-hybrid Homo sapiens
129 SGTA 6449
Co-fractionation Homo sapiens
130 SMAD6  
Affinity Capture-MS Homo sapiens
131 FOXQ1  
Affinity Capture-MS Homo sapiens
132 TRNT1 51095
Co-fractionation Homo sapiens
133 IKZF2 22807
Two-hybrid Homo sapiens
134 ZC3H3  
Affinity Capture-MS Homo sapiens
135 BRD3 8019
Affinity Capture-MS Homo sapiens
136 MDM2  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
137 TRPS1  
Affinity Capture-MS Homo sapiens
138 STX11 8676
Two-hybrid Homo sapiens
139 PPP1R15A  
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
140 RBBP8  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
141 STUB1 10273
Affinity Capture-Western Homo sapiens
PCA Homo sapiens
142 CBX4  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
143 RAI2  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
144 DZIP3  
Affinity Capture-MS Homo sapiens
145 MARK3 4140
Affinity Capture-MS Homo sapiens
146 CLPP 8192
Proximity Label-MS Homo sapiens
147 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
148 MVD 4597
Affinity Capture-MS Homo sapiens
149 TSHZ3  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
150 SHISA6  
Two-hybrid Homo sapiens
151 RNF135  
Two-hybrid Homo sapiens
152 LCORL  
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
153 NEK6 10783
Two-hybrid Homo sapiens
154 MTA1 9112
Affinity Capture-MS Homo sapiens
155 XRCC6 2547
Two-hybrid Homo sapiens
156 ZEB1  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
157 ATXN1L  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
158 FOXB1  
Affinity Capture-MS Homo sapiens
159 KAT2B  
Affinity Capture-Western Homo sapiens
160 NOL4  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
161 KEAP1 9817
Negative Genetic Homo sapiens
162 KLF3  
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Proximity Label-MS Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
163 KDM4C  
Affinity Capture-MS Homo sapiens
164 RPS4X 6191
Two-hybrid Homo sapiens
165 ZBP1  
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
166 HDAC1 3065
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
167 CWC15  
Affinity Capture-MS Homo sapiens
168 CUL4B 8450
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
169 RAB11FIP1 80223
Affinity Capture-MS Homo sapiens
170 RUNX1  
Two-hybrid Homo sapiens
171 ZFPM1 161882
Two-hybrid Homo sapiens
172 ESR1  
Affinity Capture-MS Homo sapiens
173 TGIF1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
174 RPS28 6234
Two-hybrid Homo sapiens
175 RBM4 5936
Affinity Capture-MS Homo sapiens
176 Zfpm1  
Affinity Capture-Western Mus musculus
177 LCOR 84458
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
178 HIC2 23119
Affinity Capture-MS Homo sapiens
179 RPL7A 6130
Two-hybrid Homo sapiens
180 PSMF1 9491
Two-hybrid Homo sapiens
181 KYNU  
Two-hybrid Homo sapiens
182 RIMBP3 85376
Two-hybrid Homo sapiens
183 NRIP1 8204
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
184 SOX13  
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
185 RPS29 6235
Two-hybrid Homo sapiens
186 C9orf72  
Affinity Capture-MS Homo sapiens
187 CWC22 57703
Affinity Capture-MS Homo sapiens
188 CASP8AP2  
Two-hybrid Homo sapiens
189 ZBTB42  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
190 Ctbp1 13016
Affinity Capture-Western Mus musculus
191 FOXE1  
Affinity Capture-MS Homo sapiens
192 RPA3 6119
Proximity Label-MS Homo sapiens
193 ZNF516 9658
Affinity Capture-MS Homo sapiens
194 RCOR1  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
195 RPL17 6139
Two-hybrid Homo sapiens
196 CDKN2A 1029
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
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Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here