Gene description for ARR3
Gene name
arrestin 3, retinal (X-arrestin)
Gene symbol
ARR3
Other names/aliases
ARRX
Species
Homo sapiens
Database cross references - ARR3
ExoCarta
ExoCarta_407
Entrez Gene
407
HGNC
710
MIM
301770
UniProt
P36575
ARR3 identified in exosomes derived from the following tissue/cell type
Prostate cancer cells
25844599
Prostate cancer cells
25844599
Gene ontology annotations for ARR3
Experiment description of studies that identified ARR3 in exosomes
1
Experiment ID
275
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|Alix|RAB5A
EV Cytosolic markers
✔
CD9|CD82|CD63|CD81
EV Membrane markers
✔
AIF
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25844599
Organism
Homo sapiens
Experiment description
Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors
Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T.
Journal name
Oncotarget
Publication year
2015
Sample
Prostate cancer cells
Sample name
DU145 - Docetaxel sensitive
Isolation/purification methods
Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.12-1.19 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry/Flow cytometry/Western blotting
2
Experiment ID
274
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|Alix|RAB5A
EV Cytosolic markers
✔
CD9|CD82|CD63|CD81
EV Membrane markers
✔
AIF
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25844599
Organism
Homo sapiens
Experiment description
Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors
Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T.
Journal name
Oncotarget
Publication year
2015
Sample
Prostate cancer cells
Sample name
DU145 - Docetaxel resistant
Isolation/purification methods
Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.13-1.18 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry Flow cytometry Western blotting
Protein-protein interactions for ARR3
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
AP1B1
162
Affinity Capture-Western
Homo sapiens
2
RNASE6
Two-hybrid
Homo sapiens
3
GNMT
Two-hybrid
Homo sapiens
4
SRC
6714
Affinity Capture-MS
Homo sapiens
Affinity Capture-Western
Homo sapiens
5
AP3B1
8546
Affinity Capture-MS
Homo sapiens
6
ZNF496
Two-hybrid
Homo sapiens
Affinity Capture-Western
Homo sapiens
7
RHO
Reconstituted Complex
Homo sapiens
8
CSNK2A1
1457
Biochemical Activity
Homo sapiens
9
DVL2
1856
Two-hybrid
Homo sapiens
10
CAPNS1
826
Two-hybrid
Homo sapiens
11
ARRB1
408
Affinity Capture-MS
Homo sapiens
12
CSNK2A2
1459
Biochemical Activity
Homo sapiens
13
PTAFR
Invivo
Homo sapiens
Invitro
Homo sapiens
14
AP3B2
Affinity Capture-Western
Homo sapiens
View the network
image/svg+xml
Pathways in which ARR3 is involved
No pathways found