Gene description for SULT1C2
Gene name sulfotransferase family, cytosolic, 1C, member 2
Gene symbol SULT1C2
Other names/aliases ST1C1
ST1C2
SULT1C1
humSULTC2
Species Homo sapiens
 Database cross references - SULT1C2
ExoCarta ExoCarta_6819
Vesiclepedia VP_6819
Entrez Gene 6819
HGNC 11456
MIM 602385
UniProt O00338  
 SULT1C2 identified in exosomes derived from the following tissue/cell type
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
 Gene ontology annotations for SULT1C2
Molecular Function
    aryl sulfotransferase activity GO:0004062 IBA
    aryl sulfotransferase activity GO:0004062 IDA
    protein binding GO:0005515 IPI
    sulfotransferase activity GO:0008146 IDA
Biological Process
    amine metabolic process GO:0009308 TAS
    sulfation GO:0051923 IBA
    sulfation GO:0051923 IDA
    sulfation GO:0051923 IDA
Subcellular Localization
    cytoplasm GO:0005737 IBA
    lysosome GO:0005764 IEA
    cytosol GO:0005829 TAS
 Experiment description of studies that identified SULT1C2 in exosomes
1
Experiment ID 834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for SULT1C2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ACD  
Two-hybrid Homo sapiens
2 SULT1A1 6817
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 POLL  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 OTULIN 90268
Affinity Capture-MS Homo sapiens
5 SULT1A2  
Affinity Capture-MS Homo sapiens
6 SULT1A3 6818
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 SULT1C4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 HLTF  
Two-hybrid Homo sapiens
9 TERF1 7013
Two-hybrid Homo sapiens
10 TINF2  
Two-hybrid Homo sapiens
11 SLC25A6 293
Affinity Capture-MS Homo sapiens
12 RASGRP3  
Two-hybrid Homo sapiens
13 POT1  
Two-hybrid Homo sapiens
14 SULT2B1 6820
Affinity Capture-MS Homo sapiens
15 SULT4A1  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



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