Gene description for ACSF3
Gene name acyl-CoA synthetase family member 3
Gene symbol ACSF3
Other names/aliases -
Species Homo sapiens
 Database cross references - ACSF3
ExoCarta ExoCarta_197322
Entrez Gene 197322
HGNC 27288
MIM 614245
UniProt Q4G176  
 ACSF3 identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for ACSF3
Molecular Function
    ATP binding GO:0005524 IEA
    acid-thiol ligase activity GO:0016878 IDA
    malonyl-CoA synthetase activity GO:0090409 IDA
Biological Process
    fatty acid biosynthetic process GO:0006633 IDA
    malonate catabolic process GO:0090410 IDA
    fatty acid metabolic process GO:0006631 IDA
Subcellular Localization
    mitochondrion GO:0005739 IDA
 Experiment description of studies that identified ACSF3 in exosomes
1
Experiment ID 237
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for ACSF3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which ACSF3 is involved
No pathways found





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