Gene description for ESF1
Gene name ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
Gene symbol ESF1
Other names/aliases ABTAP
C20orf6
HDCMC28P
bA526K24.1
Species Homo sapiens
 Database cross references - ESF1
ExoCarta ExoCarta_51575
Vesiclepedia VP_51575
Entrez Gene 51575
HGNC 15898
UniProt Q9H501  
 ESF1 identified in exosomes derived from the following tissue/cell type
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
 Gene ontology annotations for ESF1
Molecular Function
    RNA binding GO:0003723 HDA
    RNA binding GO:0003723 IBA
Biological Process
    rRNA processing GO:0006364 IBA
Subcellular Localization
    extracellular space GO:0005615 HDA
    nucleoplasm GO:0005654 IEA
    nucleolus GO:0005730 IEA
 Experiment description of studies that identified ESF1 in exosomes
1
Experiment ID 834
MISEV standards
EM
Biophysical techniques
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 835
MISEV standards
EM
Biophysical techniques
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for ESF1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 GNL2 29889
Affinity Capture-MS Homo sapiens
2 UBE2H 7328
Affinity Capture-MS Homo sapiens
3 CDC14B 8555
Proximity Label-MS Homo sapiens
4 RIT1 6016
Negative Genetic Homo sapiens
5 H2AFJ 55766
Affinity Capture-MS Homo sapiens
6 SENP3 26168
Affinity Capture-MS Homo sapiens
7 NOP58 51602
Co-fractionation Homo sapiens
8 ZMYND8 23613
Affinity Capture-MS Homo sapiens
9 COIL  
Proximity Label-MS Homo sapiens
10 FBXO7 25793
Affinity Capture-MS Homo sapiens
11 KPNA1 3836
Affinity Capture-MS Homo sapiens
12 KIAA0020 9933
Co-fractionation Homo sapiens
13 RPSAP58 388524
Affinity Capture-MS Homo sapiens
14 HIST1H2BG 8339
Proximity Label-MS Homo sapiens
15 ACTC1 70
Proximity Label-MS Homo sapiens
16 NOP56 10528
Proximity Label-MS Homo sapiens
17 CHCHD1  
Proximity Label-MS Homo sapiens
18 CSNK2A1 1457
Affinity Capture-MS Homo sapiens
19 PEBP1 5037
Co-fractionation Homo sapiens
20 UTP3 57050
Co-fractionation Homo sapiens
21 Nhsl1  
Affinity Capture-MS Mus musculus
22 CENPA  
Proximity Label-MS Homo sapiens
23 ANKRD50 57182
Affinity Capture-MS Homo sapiens
24 USP36  
Affinity Capture-MS Homo sapiens
25 DDX23 9416
Proximity Label-MS Homo sapiens
26 KRTAP19-7  
Affinity Capture-MS Homo sapiens
27 ARL3 403
Affinity Capture-MS Homo sapiens
28 RNPS1 10921
Affinity Capture-MS Homo sapiens
29 CDK2AP1  
Affinity Capture-MS Homo sapiens
30 MPHOSPH10 10199
Co-fractionation Homo sapiens
31 PRC1 9055
Affinity Capture-MS Homo sapiens
32 COL8A1 1295
Affinity Capture-MS Homo sapiens
33 NPM1 4869
Affinity Capture-MS Homo sapiens
34 RPS8 6202
Affinity Capture-MS Homo sapiens
35 FBL 2091
Proximity Label-MS Homo sapiens
36 POLR1E  
Proximity Label-MS Homo sapiens
37 ATP2A2 488
Cross-Linking-MS (XL-MS) Homo sapiens
38 SCD 6319
Co-fractionation Homo sapiens
39 PEA15 8682
Affinity Capture-MS Homo sapiens
40 GAGE2E 26749
Affinity Capture-MS Homo sapiens
41 AATF  
Co-fractionation Homo sapiens
42 DDX18 8886
Co-fractionation Homo sapiens
43 SERF2 10169
Affinity Capture-MS Homo sapiens
44 CALR 811
Co-fractionation Homo sapiens
45 MECP2 4204
Affinity Capture-MS Homo sapiens
46 SH3BGRL 6451
Affinity Capture-MS Homo sapiens
47 CSNK2B 1460
Affinity Capture-MS Homo sapiens
48 RPS11 6205
Affinity Capture-MS Homo sapiens
49 GAR1 54433
Affinity Capture-MS Homo sapiens
50 PES1 23481
Co-fractionation Homo sapiens
51 JPH3 57338
Affinity Capture-MS Homo sapiens
52 TMEM14B  
Affinity Capture-MS Homo sapiens
53 RPA4  
Proximity Label-MS Homo sapiens
54 IFI27L1  
Affinity Capture-MS Homo sapiens
55 CBX3 11335
Proximity Label-MS Homo sapiens
56 ACACA 31
Positive Genetic Homo sapiens
57 AKR7L 246181
Affinity Capture-MS Homo sapiens
58 Srp72  
Affinity Capture-MS Mus musculus
59 C16orf58 64755
Affinity Capture-MS Homo sapiens
60 RPL31 6160
Proximity Label-MS Homo sapiens
61 ANAPC15  
Affinity Capture-MS Homo sapiens
62 RPS6 6194
Proximity Label-MS Homo sapiens
63 ADAMTS1 9510
Affinity Capture-MS Homo sapiens
64 C1orf189  
Affinity Capture-MS Homo sapiens
65 CD3EAP  
Proximity Label-MS Homo sapiens
66 FGFBP1 9982
Affinity Capture-MS Homo sapiens
67 ABT1 29777
Affinity Capture-MS Homo sapiens
68 TCEAL7  
Affinity Capture-MS Homo sapiens
69 PSENEN  
Affinity Capture-MS Homo sapiens
70 SIRT7  
Affinity Capture-MS Homo sapiens
71 HTATSF1 27336
Co-fractionation Homo sapiens
72 NR3C1 2908
Proximity Label-MS Homo sapiens
73 DNAJC17  
Proximity Label-MS Homo sapiens
74 NXF1 10482
Affinity Capture-RNA Homo sapiens
75 MYCN  
Affinity Capture-MS Homo sapiens
76 RPA3 6119
Proximity Label-MS Homo sapiens
77 LBH  
Affinity Capture-MS Homo sapiens
78 PCBP1 5093
Affinity Capture-MS Homo sapiens
79 MYC  
Affinity Capture-MS Homo sapiens
80 DDX47 51202
Affinity Capture-MS Homo sapiens
81 DNAJC9 23234
Proximity Label-MS Homo sapiens
82 ITPKB  
Affinity Capture-MS Homo sapiens
83 RNF2  
Affinity Capture-MS Homo sapiens
84 FAM107B 83641
Affinity Capture-MS Homo sapiens
85 SEPT7 989
Co-fractionation Homo sapiens
86 TMSB4Y  
Affinity Capture-MS Homo sapiens
87 DDX52  
Co-fractionation Homo sapiens
88 NGDN  
Affinity Capture-MS Homo sapiens
89 HECTD1 25831
Affinity Capture-MS Homo sapiens
90 SIRT6  
Affinity Capture-MS Homo sapiens
91 PARP1 142
Proximity Label-MS Homo sapiens
92 FBXL6  
Affinity Capture-MS Homo sapiens
93 EHHADH 1962
Affinity Capture-MS Homo sapiens
94 2310003H01Rik  
Affinity Capture-MS Mus musculus
95 IFI6  
Affinity Capture-MS Homo sapiens
96 EZH1  
Affinity Capture-MS Homo sapiens
97 NIFK 84365
Proximity Label-MS Homo sapiens
98 DHX40  
Proximity Label-MS Homo sapiens
99 C20orf197  
Affinity Capture-MS Homo sapiens
100 NUP50 10762
Proximity Label-MS Homo sapiens
101 RPS24 6229
Proximity Label-MS Homo sapiens
102 SPCS1 28972
Affinity Capture-MS Homo sapiens
103 CIT 11113
Affinity Capture-MS Homo sapiens
104 RNF145  
Affinity Capture-MS Homo sapiens
105 KRAS 3845
Negative Genetic Homo sapiens
106 HNRNPU 3192
Affinity Capture-MS Homo sapiens
107 CYCS 54205
Affinity Capture-MS Homo sapiens
108 SMURF2 64750
Affinity Capture-MS Homo sapiens
109 Bcl7c  
Affinity Capture-MS Mus musculus
110 UQCR11  
Affinity Capture-MS Homo sapiens
111 ZBTB44  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which ESF1 is involved
No pathways found





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