Gene description for CAT
Gene name	catalase
Gene symbol	CAT
Other names/aliases	-
Species	Homo sapiens
Database cross references - CAT
ExoCarta	ExoCarta_847
Entrez Gene	847
HGNC	1516
MIM	115500
UniProt	P04040
CAT identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells	Unpublished / Not applicable
Ovarian cancer cells	23333927
Ovarian cancer cells	23333927
Platelets	25332113
Platelets	25332113
Platelets	25332113
Thymus	23844026

Gene ontology annotations for CAT

Molecular Function     NADP binding GO:0050661 IDA     metal ion binding GO:0046872 IEA     heme binding GO:0020037 IDA     protein homodimerization activity GO:0042803 IDA     receptor binding GO:0005102 IPI     aminoacylase activity GO:0004046 IEA     enzyme binding GO:0019899 IPI     oxidoreductase activity, acting on peroxide as acceptor GO:0016684 ISS     catalase activity GO:0004096 TAS     antioxidant activity GO:0016209 IDA Biological Process     hydrogen peroxide catabolic process GO:0042744 IDA     protein homotetramerization GO:0051289 IDA     response to hypoxia GO:0001666 IEA     osteoblast differentiation GO:0001649 IDA     cholesterol metabolic process GO:0008203 IEA     response to reactive oxygen species GO:0000302 TAS     positive regulation of NF-kappaB transcription factor activity GO:0051092 IEA     UV protection GO:0009650 IMP     cellular response to growth factor stimulus GO:0071363 IEA     response to hyperoxia GO:0055093 IEA     triglyceride metabolic process GO:0006641 IEA     purine nucleotide catabolic process GO:0006195 TAS     purine nucleobase metabolic process GO:0006144 TAS     aerobic respiration GO:0009060 IEA     positive regulation of phosphatidylinositol 3-kinase signaling GO:0014068 IEA     response to vitamin E GO:0033197 IEA     nucleobase-containing small molecule metabolic process GO:0055086 TAS     small molecule metabolic process GO:0044281 TAS     ureteric bud development GO:0001657 IEA     positive regulation of cell division GO:0051781 IEA     protein tetramerization GO:0051262 IDA     aging GO:0007568 IEA     negative regulation of apoptotic process GO:0043066 IMP     negative regulation of NF-kappaB transcription factor activity GO:0032088 IEA     hemoglobin metabolic process GO:0020027 IEA Subcellular Localization     plasma membrane GO:0005886 IEA     peroxisome GO:0005777 IDA     peroxisomal matrix GO:0005782 TAS     mitochondrial intermembrane space GO:0005758 IEA     peroxisomal membrane GO:0005778 ISS     lysosome GO:0005764 IEA     endoplasmic reticulum GO:0005783 IEA     extracellular exosome GO:0070062 IDA     membrane GO:0016020 IDA     focal adhesion GO:0005925 IDA     intracellular membrane-bounded organelle GO:0043231 IDA     Golgi apparatus GO:0005794 IEA     cytosol GO:0005829 IEA