Gene description for CSK
Gene name	c-src tyrosine kinase
Gene symbol	CSK
Other names/aliases	-
Species	Homo sapiens
Database cross references - CSK
ExoCarta	ExoCarta_1445
Entrez Gene	1445
HGNC	2444
MIM	124095
UniProt	P41240
CSK identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells	26054723
Neuroblastoma cells	25944692
Ovarian cancer cells	23333927
Ovarian cancer cells	23333927
Platelets	25332113
Platelets	25332113
Platelets	25332113
Thymus	23844026
Urine	19056867

Gene ontology annotations for CSK

Molecular Function     ATP binding GO:0005524 IEA     protein tyrosine kinase activity GO:0004713 TAS     protein C-terminus binding GO:0008022 TAS     identical protein binding GO:0042802 IPI     non-membrane spanning protein tyrosine kinase activity GO:0004715 IBA     protein phosphatase binding GO:0019903 IEA     receptor binding GO:0005102 IBA     protein binding GO:0005515 IPI     proline-rich region binding GO:0070064 IEA Biological Process     adherens junction organization GO:0034332 IBA     oligodendrocyte differentiation GO:0048709 IEA     protein phosphorylation GO:0006468 TAS     regulation of Fc receptor mediated stimulatory signaling pathway GO:0060368 IBA     peptidyl-tyrosine autophosphorylation GO:0038083 IBA     negative regulation of cell proliferation GO:0008285 IEA     negative regulation of kinase activity GO:0033673 IEA     T cell receptor signaling pathway GO:0050852 TAS     cell migration GO:0016477 IBA     brain development GO:0007420 IEA     blood coagulation GO:0007596 TAS     negative regulation of low-density lipoprotein particle clearance GO:0010989 IEA     negative regulation of Golgi to plasma membrane protein transport GO:0042997 IDA     negative regulation of interleukin-6 production GO:0032715 IEA     negative regulation of ERK1 and ERK2 cascade GO:0070373 IEA     regulation of cell proliferation GO:0042127 IBA     transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 IBA     epidermal growth factor receptor signaling pathway GO:0007173 TAS     negative regulation of phagocytosis GO:0050765 IEA     innate immune response GO:0045087 IBA     regulation of cytokine production GO:0001817 IBA     positive regulation of MAP kinase activity GO:0043406 IEA     T cell costimulation GO:0031295 TAS     cell differentiation GO:0030154 IBA     morphogenesis of an epithelium GO:0002009 IBA     cellular response to peptide hormone stimulus GO:0071375 IEA     platelet activation GO:0030168 TAS     negative regulation of bone resorption GO:0045779 IEA Subcellular Localization     cell-cell junction GO:0005911 IEA     cytosol GO:0005829 TAS     membrane raft GO:0045121 IEA     cytoplasm GO:0005737 TAS     extrinsic component of cytoplasmic side of plasma membrane GO:0031234 IBA     extracellular exosome GO:0070062 IDA     plasma membrane GO:0005886 TAS