Gene description for MARK3
Gene name
MAP/microtubule affinity-regulating kinase 3
Gene symbol
MARK3
Other names/aliases
CTAK1 KP78 PAR1A Par-1a
Species
Homo sapiens
Database cross references - MARK3
ExoCarta
ExoCarta_4140
Entrez Gene
4140
HGNC
6897
MIM
602678
UniProt
P27448
MARK3 identified in exosomes derived from the following tissue/cell type
Ovarian cancer cells
23333927
Ovarian cancer cells
23333927
Gene ontology annotations for MARK3
Experiment description of studies that identified MARK3 in exosomes
1
Experiment ID
211
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|Alix
EV Cytosolic markers
✔
EpCAM|TFRC
EV Membrane markers
✔
cytochrome c|GOLGA2
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
IGROV1
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
2
Experiment ID
212
ISEV standards
✔
CEM
EV Biophysical techniques
✔
TSG101|Alix
EV Cytosolic markers
✔
EpCAM|TFRC
EV Membrane markers
✔
Cytochrome C|GOLGA2
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
OVCAR-3
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
Protein-protein interactions for MARK3
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
SFN
2810
Two-hybrid
Homo sapiens
Affinity Capture-MS
Homo sapiens
2
YWHAQ
10971
Affinity Capture-MS
Homo sapiens
3
CHGB
Two-hybrid
Homo sapiens
4
ATP6V0C
527
Two-hybrid
Homo sapiens
5
YWHAG
7532
Affinity Capture-MS
Homo sapiens
6
TTR
7276
Two-hybrid
Homo sapiens
7
PNPLA2
Two-hybrid
Homo sapiens
8
RASGRF1
Affinity Capture-Western
Homo sapiens
Reconstituted Complex
Homo sapiens
9
SAAL1
Two-hybrid
Homo sapiens
10
VPS11
55823
Two-hybrid
Homo sapiens
11
YWHAB
7529
Affinity Capture-MS
Homo sapiens
12
TCEA2
Two-hybrid
Homo sapiens
13
PMPCB
Two-hybrid
Homo sapiens
View the network
image/svg+xml
Pathways in which MARK3 is involved
No pathways found