Gene ontology annotations for TPD52L1
Experiment description of studies that identified TPD52L1 in exosomes
1
Experiment ID
236
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule
mRNA
Identification method
RNA Sequencing
PubMed ID
26054723
Organism
Homo sapiens
Experiment description
Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors
"He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name
Carcinogenesis
Publication year
2015
Sample
Hepatocellular carcinoma cells
Sample name
MHCC97L
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.13-1.19 g/mL
Molecules identified in the study
Protein RNA
Methods used in the study
Western blotting Mass spectrometry RT-PCR RNA Sequencing
2
Experiment ID
834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
35333565
Organism
Homo sapiens
Experiment description
LAMP2A regulates the loading of proteins into exosomes
Authors
"Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name
Sci Adv
Publication year
2022
Sample
Retinal pigment epithelial cells
Sample name
ARPE-19
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
3
Experiment ID
835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
35333565
Organism
Homo sapiens
Experiment description
LAMP2A regulates the loading of proteins into exosomes
Authors
"Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name
Sci Adv
Publication year
2022
Sample
Retinal pigment epithelial cells
Sample name
ARPE-19
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
Protein-protein interactions for TPD52L1
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
Tpd52
Two-hybrid
Mus musculus
2
ABL2
Two-hybrid
Homo sapiens
3
TNFRSF1B
Affinity Capture-MS
Homo sapiens
4
PSMC3
5702
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
5
GRIN3B
Affinity Capture-MS
Homo sapiens
6
LAMTOR1
55004
Proximity Label-MS
Homo sapiens
7
NPM3
10360
Co-fractionation
Homo sapiens
8
YWHAB
7529
Affinity Capture-MS
Homo sapiens
9
TPD52L1
7164
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
10
KCTD12
115207
Affinity Capture-MS
Homo sapiens
11
S100A2
6273
Co-fractionation
Homo sapiens
12
MAL2
114569
Two-hybrid
Homo sapiens
13
AZIN2
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
14
AGMAT
Affinity Capture-MS
Homo sapiens
15
TPD52L2
7165
Two-hybrid
Homo sapiens
Affinity Capture-MS
Homo sapiens
Two-hybrid
Homo sapiens
Affinity Capture-MS
Homo sapiens
16
GSKIP
Affinity Capture-MS
Homo sapiens
17
HDAC1
3065
Two-hybrid
Homo sapiens
18
UCHL3
7347
Co-fractionation
Homo sapiens
19
PBX3
Two-hybrid
Homo sapiens
20
RNF40
9810
Co-fractionation
Homo sapiens
21
TPD52
7163
Two-hybrid
Homo sapiens
Affinity Capture-MS
Homo sapiens
Two-hybrid
Homo sapiens
Affinity Capture-MS
Homo sapiens
22
UBR5
51366
Co-fractionation
Homo sapiens
23
EIF3J
8669
Two-hybrid
Homo sapiens
24
TPD52L3
Affinity Capture-MS
Homo sapiens
25
ISYNA1
51477
Co-fractionation
Homo sapiens
26
EPN3
55040
Affinity Capture-MS
Homo sapiens
27
GABBR1
Affinity Capture-MS
Homo sapiens
28
GOPC
57120
Affinity Capture-MS
Homo sapiens
29
YWHAQ
10971
Affinity Capture-MS
Homo sapiens
30
GPR135
Two-hybrid
Homo sapiens
31
YAE1D1
Two-hybrid
Homo sapiens
32
TXNL4A
10907
Affinity Capture-MS
Homo sapiens
33
PAK6
56924
Two-hybrid
Homo sapiens
View the network
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Pathways in which TPD52L1 is involved