Gene description for POGLUT1
Gene name protein O-glucosyltransferase 1
Gene symbol POGLUT1
Other names/aliases C3orf9
CLP46
KDELCL1
KTELC1
MDS010
MDSRP
Rumi
hCLP46
Species Homo sapiens
 Database cross references - POGLUT1
ExoCarta ExoCarta_56983
Vesiclepedia VP_56983
Entrez Gene 56983
HGNC 22954
MIM 615618
UniProt Q8NBL1  
 POGLUT1 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Mesenchymal stem cells 36408942    
 Gene ontology annotations for POGLUT1
Molecular Function
    UDP-glucosyltransferase activity GO:0035251 IBA
    UDP-glucosyltransferase activity GO:0035251 IDA
    UDP-glucosyltransferase activity GO:0035251 IMP
    UDP-xylosyltransferase activity GO:0035252 IBA
    UDP-xylosyltransferase activity GO:0035252 IMP
    glucosyltransferase activity GO:0046527 IDA
    EGF-domain serine glucosyltransferase activity GO:0140561 IEA
    EGF-domain serine xylosyltransferase activity GO:0140562 IEA
Biological Process
    somitogenesis GO:0001756 IEA
    protein O-linked glycosylation GO:0006493 IBA
    protein O-linked glycosylation GO:0006493 IDA
    gastrulation GO:0007369 IEA
    regulation of gastrulation GO:0010470 ISS
    protein O-linked glycosylation via serine GO:0018242 IDA
    protein O-linked glycosylation via serine GO:0018242 IMP
    positive regulation of Notch signaling pathway GO:0045747 IBA
    positive regulation of Notch signaling pathway GO:0045747 IMP
    axial mesoderm development GO:0048318 IEA
    paraxial mesoderm development GO:0048339 IEA
    muscle tissue development GO:0060537 IMP
    circulatory system development GO:0072359 IEA
Subcellular Localization
    endoplasmic reticulum GO:0005783 IDA
    endoplasmic reticulum lumen GO:0005788 IDA
    endomembrane system GO:0012505 IBA
 Experiment description of studies that identified POGLUT1 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for POGLUT1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CCL3  
Affinity Capture-MS Homo sapiens
2 UGGT2 55757
Affinity Capture-MS Homo sapiens
3 FBXO2 26232
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 CSGALNACT2 55454
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 CEACAM8 1088
Affinity Capture-MS Homo sapiens
6 LCN6  
Affinity Capture-MS Homo sapiens
7 FSTL4  
Affinity Capture-MS Homo sapiens
8 HPN  
Affinity Capture-MS Homo sapiens
9 CFC1  
Affinity Capture-MS Homo sapiens
10 MFAP4 4239
Affinity Capture-MS Homo sapiens
11 TCN2 6948
Affinity Capture-MS Homo sapiens
12 NR2F2  
Co-fractionation Homo sapiens
13 F9 2158
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
14 ST14 6768
Affinity Capture-MS Homo sapiens
15 UGT1A10  
Affinity Capture-MS Homo sapiens
16 LIPG 9388
Affinity Capture-MS Homo sapiens
17 MYCBP2 23077
Affinity Capture-MS Homo sapiens
18 ELSPBP1  
Affinity Capture-MS Homo sapiens
19 CLGN 1047
Affinity Capture-MS Homo sapiens
20 ACADS 35
Co-fractionation Homo sapiens
21 TAZ  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
22 TMEM25  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
23 CALR3  
Proximity Label-MS Homo sapiens
24 PLAUR 5329
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
25 OS9 10956
Affinity Capture-MS Homo sapiens
26 A2M 2
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
27 LYZL6  
Affinity Capture-MS Homo sapiens
28 MSTN  
Affinity Capture-MS Homo sapiens
29 UBR5 51366
Affinity Capture-MS Homo sapiens
30 SDF2L1 23753
Affinity Capture-MS Homo sapiens
31 PIGT 51604
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
32 C1orf54  
Affinity Capture-MS Homo sapiens
33 DHH  
Affinity Capture-MS Homo sapiens
34 CD160  
Affinity Capture-MS Homo sapiens
35 DHFRL1  
Affinity Capture-MS Homo sapiens
36 LYPD4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
37 C1QTNF7  
Affinity Capture-MS Homo sapiens
38 TMPRSS13  
Affinity Capture-MS Homo sapiens
39 LY86  
Affinity Capture-MS Homo sapiens
40 CASP4  
Co-fractionation Homo sapiens
41 LY6H  
Affinity Capture-MS Homo sapiens
42 C7orf34  
Affinity Capture-MS Homo sapiens
43 HNRNPDL 9987
Co-fractionation Homo sapiens
44 FBXO45 200933
Affinity Capture-MS Homo sapiens
45 PRG3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
46 CANX 821
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
47 LRRC59 55379
Proximity Label-MS Homo sapiens
48 C1QA 712
Affinity Capture-MS Homo sapiens
49 GGH 8836
Affinity Capture-MS Homo sapiens
50 PON2 5445
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
51 DHX29 54505
Co-fractionation Homo sapiens
52 KCMF1 56888
Affinity Capture-MS Homo sapiens
53 PDGFRA 5156
Affinity Capture-MS Homo sapiens
54 PRG2  
Affinity Capture-MS Homo sapiens
55 PI15  
Affinity Capture-MS Homo sapiens
56 RLN1  
Affinity Capture-MS Homo sapiens
57 GAA 2548
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
58 FBXO6 26270
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
59 IL5RA  
Affinity Capture-MS Homo sapiens
60 LYZL1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
61 UBR1 197131
Affinity Capture-MS Homo sapiens
62 ANPEP 290
Co-fractionation Homo sapiens
63 NAAA  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
64 BST1 683
Affinity Capture-MS Homo sapiens
65 SCGB2A2  
Affinity Capture-MS Homo sapiens
66 PSCA 8000
Affinity Capture-MS Homo sapiens
67 ITGB4 3691
Co-fractionation Homo sapiens
68 ISLR 3671
Affinity Capture-MS Homo sapiens
69 MAGT1 84061
Affinity Capture-MS Homo sapiens
70 EDDM3B  
Affinity Capture-MS Homo sapiens
71 CD46 4179
Co-fractionation Homo sapiens
72 LYZL2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
73 AHSA1 10598
Co-fractionation Homo sapiens
74 ART3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
75 TXNDC16 57544
Affinity Capture-MS Homo sapiens
76 SCGB2A1 4246
Affinity Capture-MS Homo sapiens
77 LGI1  
Affinity Capture-MS Homo sapiens
78 TP53 7157
Negative Genetic Homo sapiens
79 SCGB1D1  
Affinity Capture-MS Homo sapiens
80 DPEP2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
81 UQCC1 55245
Affinity Capture-MS Homo sapiens
82 HECTD3 79654
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
83 ZZEF1 23140
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
84 SQSTM1 8878
Affinity Capture-MS Homo sapiens
85 NCR3  
Affinity Capture-MS Homo sapiens
86 GNA11 2767
Co-fractionation Homo sapiens
87 DHX40  
Co-fractionation Homo sapiens
88 CLEC12B  
Affinity Capture-MS Homo sapiens
89 SUSD4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
90 UBR4 23352
Affinity Capture-MS Homo sapiens
91 ALPP 250
Affinity Capture-MS Homo sapiens
92 PTPRK 5796
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
93 PTCH1  
Affinity Capture-MS Homo sapiens
94 TRAV20  
Affinity Capture-MS Homo sapiens
95 TIMP3 7078
Affinity Capture-MS Homo sapiens
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