Gene description for HLA-E
Gene name major histocompatibility complex, class I, E
Gene symbol HLA-E
Other names/aliases EA1.2
EA2.1
HLA-6.2
MHC
QA1
Species Homo sapiens
 Database cross references - HLA-E
ExoCarta ExoCarta_3133
Vesiclepedia VP_3133
Entrez Gene 3133
HGNC 4962
MIM 143010
UniProt P13747  
 HLA-E identified in sEVs derived from the following tissue/cell type
B cells 20458337    
B cells 20458337    
B cells 20458337    
Bone marrow cells 15908444    
Bronchoalveolar lavage fluid 14582906    
Colorectal cancer cells 19837982    
Colorectal cancer cells 15940614    
Dendritic cells 14582906    
Malignant ascites 12147373    
Malignant pleural effusions 12147373    
Mast cells 15908444    
Melanoma cells 11231627    
Mesothelioma cells 15111327    
Neuroblastoma cells 25944692    
Plasma 15908444    
Platelets 25332113    
Platelets 25332113    
Platelets 25332113    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
T cells 11907077    
Urine 19056867    
 Gene ontology annotations for HLA-E
Molecular Function
    signaling receptor binding GO:0005102 IBA
    signaling receptor binding GO:0005102 IPI
    protein binding GO:0005515 IPI
    beta-2-microglobulin binding GO:0030881 IDA
    beta-2-microglobulin binding GO:0030881 IMP
    MHC class I protein binding GO:0042288 IDA
    peptide antigen binding GO:0042605 IBA
    peptide antigen binding GO:0042605 IDA
    peptide antigen binding GO:0042605 IMP
    T cell receptor binding GO:0042608 IDA
    natural killer cell lectin-like receptor binding GO:0046703 IPI
Biological Process
    positive regulation of antibody-dependent cellular cytotoxicity GO:0001815 IDA
    positive regulation of T cell mediated cytotoxicity GO:0001916 IBA
    positive regulation of T cell mediated cytotoxicity GO:0001916 IDA
    adaptive immune response GO:0002250 IDA
    antigen processing and presentation of endogenous peptide antigen via MHC class Ib GO:0002476 IBA
    antigen processing and presentation of endogenous peptide antigen via MHC class Ib GO:0002476 IDA
    antigen processing and presentation of exogenous peptide antigen via MHC class Ib GO:0002477 IDA
    antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent GO:0002486 IBA
    natural killer cell tolerance induction GO:0002519 IDA
    positive regulation of immunoglobulin production GO:0002639 IDA
    regulation of natural killer cell mediated immunity GO:0002715 IDA
    positive regulation of natural killer cell mediated immunity GO:0002717 IDA
    positive regulation of natural killer cell cytokine production GO:0002729 IDA
    immune response GO:0006955 IBA
    antibacterial humoral response GO:0019731 IDA
    positive regulation of interleukin-13 production GO:0032736 IDA
    positive regulation of interleukin-4 production GO:0032753 IDA
    positive regulation of TRAIL production GO:0032759 IDA
    positive regulation of tumor necrosis factor production GO:0032760 IDA
    negative regulation of natural killer cell activation GO:0032815 IDA
    positive regulation of natural killer cell activation GO:0032816 IDA
    positive regulation of natural killer cell proliferation GO:0032819 IDA
    CD8-positive, alpha-beta T cell activation GO:0036037 IDA
    negative regulation of T cell proliferation GO:0042130 IDA
    protection from natural killer cell mediated cytotoxicity GO:0042270 IDA
    innate immune response GO:0045087 IEA
    negative regulation of natural killer cell mediated cytotoxicity GO:0045953 IDA
    positive regulation of natural killer cell mediated cytotoxicity GO:0045954 IDA
    defense response to Gram-positive bacterium GO:0050830 IDA
    positive regulation of CD8-positive, alpha-beta T cell proliferation GO:2000566 IDA
    positive regulation of CD8-positive, alpha-beta T cell activation GO:2001187 IDA
Subcellular Localization
    Golgi membrane GO:0000139 TAS
    extracellular space GO:0005615 IBA
    plasma membrane GO:0005886 IDA
    plasma membrane GO:0005886 TAS
    external side of plasma membrane GO:0009897 IBA
    cell surface GO:0009986 IDA
    ER to Golgi transport vesicle membrane GO:0012507 TAS
    phagocytic vesicle membrane GO:0030670 TAS
    early endosome membrane GO:0031901 TAS
    MHC class Ib protein complex GO:0032398 IDA
    MHC class I protein complex GO:0042612 IDA
    recycling endosome membrane GO:0055038 TAS
    extracellular exosome GO:0070062 HDA
    lumenal side of endoplasmic reticulum membrane GO:0098553 TAS
 Experiment description of studies that identified HLA-E in sEVs
1
Experiment ID 79
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 1
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
2
Experiment ID 80
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
3
Experiment ID 81
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
4
Experiment ID 42
MISEV standards
✔
EM
Biophysical techniques
✔
CD86|TFRC|LAMP2|ITGA2B|CD63|CD9|MHCI|CD81
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 15908444    
Organism Homo sapiens
Experiment description Exosomal-like vesicles are present in human blood plasma.
Authors "Caby MP, Lankar D, Vincendeau-Scherrer C, Raposo G, Bonnerot C"
Journal name INTIMM
Publication year 2005
Sample Bone marrow cells
Sample name PBMC
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
5
Experiment ID 49
MISEV standards
✔
EM|IEM
Biophysical techniques
✔
CD63|CD86
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method FACS
PubMed ID 14582906    
Organism Homo sapiens
Experiment description Exosomes with major histocompatibility complex class II and co-stimulatory molecules are present in human BAL fluid.
Authors "Admyre C, Grunewald J, Thyberg J, Gripenback S, Tornling G, Eklund A, Scheynius A, Gabrielsson S"
Journal name ERJ
Publication year 2003
Sample Bronchoalveolar lavage fluid
Sample name Bronchoalveolar lavage fluid
Isolation/purification methods Differential centrifugation
Immunobeads (EpCAM)
Flotation density -
Molecules identified in the study Protein
Methods used in the study FACS
Immunoelectron Microscopy
6
Experiment ID 21
MISEV standards
✔
EM|IEM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD63
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry   
PubMed ID 19837982    
Organism Homo sapiens
Experiment description Proteomic and bioinformatic analysis of immunoaffinity-purified exosomes derived from the human colon tumor cell line LIM1215.
Authors "Suresh Mathivanan, Justin W.E. Lim, Bow J. Tauro, Hong Ji, Robert L. Moritz and Richard J. Simpson"
Journal name MCP
Publication year 2009
Sample Colorectal cancer cells
Sample name LIM1215
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.10-1.12 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [Orbitrap]
Western blotting
7
Experiment ID 22
MISEV standards
✘ Biophysical techniques
✔
CD63
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method FACS
PubMed ID 15940614    
Organism Homo sapiens
Experiment description Human colorectal cancer cells induce T-cell death through release of proapoptotic microvesicles: role in immune escape.
Authors "Huber V, Fais S, Iero M, Lugini L, Canese P, Squarcina P, Zaccheddu A, Colone M, Arancia G, Gentile M, Seregni E, Valenti R, Ballabio G, Belli F, Leo E, Parmiani G, Rivoltini L."
Journal name GASTRO
Publication year 2005
Sample Colorectal cancer cells
Sample name SW403
1869col
CRC28462
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Immunoelectron Microscopy
FACS
8
Experiment ID 50
MISEV standards
✔
EM|IEM
Biophysical techniques
✔
CD63|CD87
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method FACS
PubMed ID 14582906    
Organism Homo sapiens
Experiment description Exosomes with major histocompatibility complex class II and co-stimulatory molecules are present in human BAL fluid.
Authors "Admyre C, Grunewald J, Thyberg J, Gripenback S, Tornling G, Eklund A, Scheynius A, Gabrielsson S"
Journal name ERJ
Publication year 2003
Sample Dendritic cells
Sample name Monocyte-derived dendritic cells
Isolation/purification methods Differential centrifugation
Immunobeads (EpCAM)
Flotation density -
Molecules identified in the study Protein
Methods used in the study FACS
Immunoelectron Microscopy
9
Experiment ID 56
MISEV standards
✔
EM
Biophysical techniques
✔
HSC70|MHCI|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 12147373    
Organism Homo sapiens
Experiment description Malignant effusions and immunogenic tumour-derived exosomes.
Authors "Andre F, Schartz NE, Movassagh M, Flament C, Pautier P, Morice P, Pomel C, Lhomme C, Escudier B, Le Chevalier T, Tursz T, Amigorena S, Raposo G, Angevin E, Zitvogel L"
Journal name LANCET
Publication year 2002
Sample Malignant ascites
Sample name Malignant ascites
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.18 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
10
Experiment ID 55
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Immunoelectron Microscopy
PubMed ID 12147373    
Organism Homo sapiens
Experiment description Malignant effusions and immunogenic tumour-derived exosomes.
Authors "Andre F, Schartz NE, Movassagh M, Flament C, Pautier P, Morice P, Pomel C, Lhomme C, Escudier B, Le Chevalier T, Tursz T, Amigorena S, Raposo G, Angevin E, Zitvogel L"
Journal name LANCET
Publication year 2002
Sample Malignant pleural effusions
Sample name Malignant pleural effusions
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.18 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
11
Experiment ID 41
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|MHCI|CD9|CD81|TFRC|LAMP2
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 15908444    
Organism Homo sapiens
Experiment description Exosomal-like vesicles are present in human blood plasma.
Authors "Caby MP, Lankar D, Vincendeau-Scherrer C, Raposo G, Bonnerot C"
Journal name INTIMM
Publication year 2005
Sample Mast cells
Sample name HMC-1
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
FACS
Immunoelectron Microscopy
12
Experiment ID 24
MISEV standards
✔
EM
Biophysical techniques
✔
HSC70|MHCI
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 11231627    
Organism Homo sapiens
Experiment description Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming.
Authors "Wolfers J, Lozier A, Raposo G, Regnault A, Thery C, Masurier C, Flament C, Pouzieux S, Faure F, Tursz T, Angevin E, Amigorena S, Zitvogel L"
Journal name NM
Publication year 2001
Sample Melanoma cells
Sample name Fon
Mel-888
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
13
Experiment ID 25
MISEV standards
✔
IEM
Biophysical techniques
✔
HSP90|beta-tubulin
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 15111327    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes secreted by human mesothelioma cells.
Authors "Hegmans JP, Bard MP, Hemmes A, Luider TM, Kleijmeer MJ, Prins JB, Zitvogel L, Burgers SA, Hoogsteden HC, Lambrecht BN."
Journal name AJP
Publication year 2004
Sample Mesothelioma cells
Sample name PMR-MM7
PMR-MM8
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
14
Experiment ID 224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
15
Experiment ID 40
MISEV standards
✔
EM|IEM
Biophysical techniques
✔
CD63|CD9|MHCII|TFRC|LAMP2|ITGA2B
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 15908444    
Organism Homo sapiens
Experiment description Exosomal-like vesicles are present in human blood plasma.
Authors "Caby MP, Lankar D, Vincendeau-Scherrer C, Raposo G, Bonnerot C"
Journal name INTIMM
Publication year 2005
Sample Plasma
Sample name Plasma - Normal
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density 1.15-1.27 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
FACS
Immunoelectron Microscopy
16
Experiment ID 231
MISEV standards
✘ Biophysical techniques
✔
Alix|CD63|CD9
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Western blotting
Mass spectrometry
17
Experiment ID 232
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
18
Experiment ID 233
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
19
Experiment ID 834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
20
Experiment ID 835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
21
Experiment ID 18
MISEV standards
✔
EM
Biophysical techniques
✔
CD63
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method FACS
PubMed ID 11907077    
Organism Homo sapiens
Experiment description TCR activation of human T cells induces the production of exosomes bearing the TCR/CD3/zeta complex.
Authors "Blanchard N, Lankar D, Faure F, Regnault A, Dumont C, Raposo G, Hivroz C"
Journal name JIMMU
Publication year 2002
Sample T cells
Sample name Jurkat
T cell blasts
Isolation/purification methods Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study FACS
22
Experiment ID 63
MISEV standards
✘ Biophysical techniques
✔
AQP2
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for HLA-E
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 WDFY3 23001
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
2 F2RL1  
Two-hybrid Homo sapiens
3 GALNT12 79695
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 CALR 811
Affinity Capture-Western Homo sapiens
5 MR1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 ARFGEF2 10564
Affinity Capture-MS Homo sapiens
7 BTNL2  
Affinity Capture-MS Homo sapiens
8 TMEM106A  
Affinity Capture-MS Homo sapiens
9 CNTNAP3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 HLA-DRB3 3125
Affinity Capture-MS Homo sapiens
11 FAM127A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
12 SORT1 6272
Affinity Capture-MS Homo sapiens
13 HLA-G 3135
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
14 ATF6  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
15 PRF1  
Affinity Capture-MS Homo sapiens
16 METTL13 51603
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 SEMA6B 10501
Affinity Capture-MS Homo sapiens
18 B2M 567
Co-crystal Structure Homo sapiens
19 FCGRT 2217
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
20 EIF2AK3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
21 CNNM1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
22 PRG2  
Affinity Capture-MS Homo sapiens
23 LRFN3  
Affinity Capture-MS Homo sapiens
24 ECEL1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
25 LRIG1 26018
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
26 FAM189B  
Affinity Capture-MS Homo sapiens
27 MADD 8567
Affinity Capture-MS Homo sapiens
28 KLRD1  
Reconstituted Complex Homo sapiens
29 NDST1 3340
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
30 SURF1  
Affinity Capture-MS Homo sapiens
31 ASPH 444
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
32 DDX58 23586
Affinity Capture-RNA Homo sapiens
33 ITGA6 3655
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
34 EDEM2  
Affinity Capture-MS Homo sapiens
35 ROR2 4920
Affinity Capture-MS Homo sapiens
36 HLA-DPB1 3115
Affinity Capture-MS Homo sapiens
37 SFTPC  
Affinity Capture-MS Homo sapiens
38 ATF6B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
39 MGAT5 4249
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 ABCA3 21
Affinity Capture-MS Homo sapiens
41 ADAM21  
Affinity Capture-MS Homo sapiens
42 BRICD5  
Affinity Capture-MS Homo sapiens
43 PBXIP1 57326
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
44 MAN2A2 4122
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
45 XRCC6BP1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
46 KCNJ8  
Affinity Capture-MS Homo sapiens
47 BACE2 25825
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
48 UGT1A7 54577
Affinity Capture-MS Homo sapiens
49 PTCD2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
50 HLA-F 3134
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
51 HLA-B 3106
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
52 TCTN2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
53 HLA-H 3136
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
54 DNAJC16  
Affinity Capture-MS Homo sapiens
55 CLEC2B  
Affinity Capture-MS Homo sapiens
56 NEK4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
57 C9orf72  
Affinity Capture-MS Homo sapiens
58 PLXNB2 23654
Affinity Capture-MS Homo sapiens
59 PLXNA3 55558
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
60 HLA-DRB1 3123
Affinity Capture-MS Homo sapiens
61 EPHB4 2050
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
62 HLA-A 3105
Affinity Capture-MS Homo sapiens
63 TMEM131  
Affinity Capture-MS Homo sapiens
64 NDST2  
Affinity Capture-MS Homo sapiens
65 GAS6 2621
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
66 LRRC24  
Affinity Capture-MS Homo sapiens
67 TAP2 6891
Affinity Capture-Western Homo sapiens
68 HLA-C 3107
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
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Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here