Gene description for SLC39A13
Gene name solute carrier family 39 (zinc transporter), member 13
Gene symbol SLC39A13
Other names/aliases -
Species Homo sapiens
 Database cross references - SLC39A13
ExoCarta ExoCarta_91252
Vesiclepedia VP_91252
Entrez Gene 91252
HGNC 20859
MIM 608735
UniProt Q96H72  
 SLC39A13 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for SLC39A13
Molecular Function
    zinc ion transmembrane transporter activity GO:0005385 IBA
    zinc ion transmembrane transporter activity GO:0005385 IC
    zinc ion transmembrane transporter activity GO:0005385 IDA
    zinc ion transmembrane transporter activity GO:0005385 IMP
    protein binding GO:0005515 IPI
    protein homodimerization activity GO:0042803 IPI
Biological Process
    zinc ion transport GO:0006829 IMP
    intracellular zinc ion homeostasis GO:0006882 IBA
    intracellular zinc ion homeostasis GO:0006882 IDA
    intracellular zinc ion homeostasis GO:0006882 ISS
    brown fat cell differentiation GO:0050873 ISS
    connective tissue development GO:0061448 IMP
    zinc ion transmembrane transport GO:0071577 IBA
    zinc ion transmembrane transport GO:0071577 IDA
    zinc ion transmembrane transport GO:0071577 ISS
Subcellular Localization
    Golgi membrane GO:0000139 IC
    Golgi membrane GO:0000139 IDA
    endoplasmic reticulum membrane GO:0005789 IDA
    Golgi apparatus GO:0005794 IDA
    Golgi apparatus GO:0005794 ISS
    membrane GO:0016020 IDA
    cytoplasmic vesicle membrane GO:0030659 IMP
    perinuclear region of cytoplasm GO:0048471 ISS
 Experiment description of studies that identified SLC39A13 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for SLC39A13
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CREB3  
Two-hybrid Homo sapiens
2 REL 5966
Two-hybrid Homo sapiens
3 OPRM1 4988
Two-hybrid Homo sapiens
4 KIR2DL4  
Affinity Capture-MS Homo sapiens
5 CD40 958
Two-hybrid Homo sapiens
6 TCF4  
Two-hybrid Homo sapiens
7 F2RL1  
Two-hybrid Homo sapiens
8 VHL  
Negative Genetic Homo sapiens
9 PGRMC2 10424
Two-hybrid Homo sapiens
10 SLC16A2  
Two-hybrid Homo sapiens
11 DDX58 23586
Affinity Capture-RNA Homo sapiens
View the network image/svg+xml
 Pathways in which SLC39A13 is involved
No pathways found





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