Gene description for CDK18
Gene name
cyclin-dependent kinase 18
Gene symbol
CDK18
Other names/aliases
PCTAIRE PCTAIRE3 PCTK3
Species
Homo sapiens
Database cross references - CDK18
ExoCarta
ExoCarta_5129
Entrez Gene
5129
HGNC
8751
MIM
169190
UniProt
Q07002
CDK18 identified in exosomes derived from the following tissue/cell type
Squamous carcinoma cells
20124223
Thymus
23844026
Gene ontology annotations for CDK18
Experiment description of studies that identified CDK18 in exosomes
1
Experiment ID
191
ISEV standards
✘
EV Biophysical techniques
✔
Alix
EV Cytosolic markers
✔
CD81|CD9
EV Membrane markers
✘
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
20124223
Organism
Homo sapiens
Experiment description
Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors
Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK.
Journal name
Mol Cell Proteomics
Publication year
2010
Sample
Squamous carcinoma cells
Sample name
Squamous carcinoma cell (A431)
Isolation/purification methods
Differential centrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
2
Experiment ID
217
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101
EV Cytosolic markers
✔
CD81|CD9|CD63
EV Membrane markers
✘
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23844026
Organism
Homo sapiens
Experiment description
Characterization of human thymic exosomes.
Authors
Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name
PLoS One
Publication year
2013
Sample
Thymus
Sample name
Normal-Thymus
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
Protein-protein interactions for CDK18
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
DIPA
Two-hybrid
Homo sapiens
2
CCNK
Two-hybrid
Homo sapiens
View the network
image/svg+xml
Pathways in which CDK18 is involved
No pathways found