Gene description for FUBP1
Gene name far upstream element (FUSE) binding protein 1
Gene symbol FUBP1
Other names/aliases FBP
FUBP
hDH V
Species Homo sapiens
 Database cross references - FUBP1
ExoCarta ExoCarta_8880
Entrez Gene 8880
HGNC 4004
MIM 603444
UniProt Q96AE4  
 FUBP1 identified in exosomes derived from the following tissue/cell type
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
 Gene ontology annotations for FUBP1
Molecular Function
    sequence-specific DNA binding transcription factor activity GO:0003700 TAS
    RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription GO:0001205 IEA
    poly(A) RNA binding GO:0044822 IDA
    protein binding GO:0005515 IPI
    single-stranded DNA binding GO:0003697 TAS
Biological Process
    positive regulation of gene expression GO:0010628 IDA
    positive regulation of transcription from RNA polymerase II promoter GO:0045944 IEA
    transcription from RNA polymerase II promoter GO:0006366 TAS
Subcellular Localization
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 IDA
 Experiment description of studies that identified FUBP1 in exosomes
1
Experiment ID 211
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|Alix
EV Cytosolic markers
✔
EpCAM|TFRC
EV Membrane markers
✔
cytochrome c|GOLGA2
EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 212
ISEV standards
✔
CEM
EV Biophysical techniques
✔
TSG101|Alix
EV Cytosolic markers
✔
EpCAM|TFRC
EV Membrane markers
✔
Cytochrome C|GOLGA2
EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for FUBP1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 IMMT 10989
Invitro Homo sapiens
2 CELF1 10658
Two-hybrid Homo sapiens
3 SMN1 6606
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
4 SNCG 6623
Affinity Capture-MS Homo sapiens
5 MAPK14 1432
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
6 VIM 7431
Two-hybrid Homo sapiens
7 CCNH  
Invitro Homo sapiens
8 GTF2H1 2965
Invivo Homo sapiens
Invitro Homo sapiens
9 TLE1  
Two-hybrid Homo sapiens
10 CHD3  
Two-hybrid Homo sapiens
11 CRMP1 1400
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which FUBP1 is involved
No pathways found





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