Gene description for CTDNEP1
Gene name CTD nuclear envelope phosphatase 1
Gene symbol CTDNEP1
Other names/aliases DULLARD
HSA011916
NET56
Species Homo sapiens
 Database cross references - CTDNEP1
ExoCarta ExoCarta_23399
Entrez Gene 23399
HGNC 19085
MIM 610684
UniProt O95476  
 CTDNEP1 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for CTDNEP1
Molecular Function
    protein serine/threonine phosphatase activity GO:0004722 TAS
    protein binding GO:0005515 IPI
Biological Process
    positive regulation of triglyceride biosynthetic process GO:0010867 IGI
    nuclear envelope organization GO:0006998 IDA
    gamete generation GO:0007276 IEA
    mesoderm development GO:0007498 IEA
    protein dephosphorylation GO:0006470 IDA
    protein localization to nucleus GO:0034504 IDA
    mitotic cell cycle GO:0000278 TAS
    mitotic nuclear envelope disassembly GO:0007077 TAS
    positive regulation of canonical Wnt signaling pathway GO:0090263 IEA
Subcellular Localization
    cytoplasm GO:0005737 IDA
    endoplasmic reticulum membrane GO:0005789 IDA
    Nem1-Spo7 phosphatase complex GO:0071595 IDA
    nuclear membrane GO:0031965 IDA
    integral component of membrane GO:0016021 IEA
    nuclear envelope GO:0005635 TAS
 Experiment description of studies that identified CTDNEP1 in exosomes
1
Experiment ID 126
ISEV standards
✘ EV Biophysical techniques
✔
GAPDH
EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for CTDNEP1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which CTDNEP1 is involved
PathwayEvidenceSource
Depolymerisation of the Nuclear Lamina TAS Reactome





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