Gene description for SLC35B1
Gene name solute carrier family 35, member B1
Gene symbol SLC35B1
Other names/aliases UGTREL1
Species Homo sapiens
 Database cross references - SLC35B1
ExoCarta ExoCarta_10237
Vesiclepedia VP_10237
Entrez Gene 10237
HGNC 20798
MIM 610790
UniProt P78383  
 SLC35B1 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for SLC35B1
Molecular Function
    UDP-galactose transmembrane transporter activity GO:0005459 IBA
    UDP-glucose transmembrane transporter activity GO:0005460 IBA
    ATP:ADP antiporter activity GO:0005471 IDA
    protein binding GO:0005515 IPI
Biological Process
    UDP-glucose transmembrane transport GO:0015786 IEA
    ADP transport GO:0015866 IEA
    ATP transport GO:0015867 IEA
    UDP-galactose transmembrane transport GO:0072334 IBA
Subcellular Localization
    Golgi membrane GO:0000139 IBA
    endoplasmic reticulum membrane GO:0005789 IBA
    endoplasmic reticulum membrane GO:0005789 IDA
    intracellular membrane-bounded organelle GO:0043231 TAS
 Experiment description of studies that identified SLC35B1 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for SLC35B1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HRH1  
Two-hybrid Homo sapiens
2 RIT1 6016
Negative Genetic Homo sapiens
3 FZD7 8324
Two-hybrid Homo sapiens
4 VAPA 9218
Two-hybrid Homo sapiens
5 PGRMC1 10857
Affinity Capture-MS Homo sapiens
6 TCERG1 10915
Affinity Capture-MS Homo sapiens
7 B4galt1  
Affinity Capture-MS Mus musculus
8 EGFR 1956
Negative Genetic Homo sapiens
9 FKBP8 23770
Two-hybrid Homo sapiens
10 CD79A  
Two-hybrid Homo sapiens
11 CREB3L1  
Two-hybrid Homo sapiens
12 APP 351
Reconstituted Complex Homo sapiens
13 GPR152  
Two-hybrid Homo sapiens
14 PTPN5  
Two-hybrid Homo sapiens
15 Hnrnpa3 229279
Affinity Capture-MS Mus musculus
16 PDZK1IP1 10158
Two-hybrid Homo sapiens
17 CCDC107  
Two-hybrid Homo sapiens
18 FZD5 7855
Two-hybrid Homo sapiens
19 C10orf54 64115
Two-hybrid Homo sapiens
20 KRAS 3845
Negative Genetic Homo sapiens
21 BNIP3 664
Two-hybrid Homo sapiens
22 ARL13B 200894
Two-hybrid Homo sapiens
23 ANAPC11  
Affinity Capture-MS Homo sapiens
24 MFF 56947
Two-hybrid Homo sapiens
25 PGRMC2 10424
Affinity Capture-MS Homo sapiens
26 DRD2  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which SLC35B1 is involved
No pathways found





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