Gene description for EVI2B
Gene name ecotropic viral integration site 2B
Gene symbol EVI2B
Other names/aliases CD361
D17S376
EVDB
Species Homo sapiens
 Database cross references - EVI2B
ExoCarta ExoCarta_2124
Vesiclepedia VP_2124
Entrez Gene 2124
HGNC 3500
MIM 158381
UniProt P34910  
 EVI2B identified in exosomes derived from the following tissue/cell type
B cells 20458337    
B cells 20458337    
 Gene ontology annotations for EVI2B
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    positive regulation of granulocyte differentiation GO:0030854 IMP
    positive regulation of granulocyte differentiation GO:0030854 ISS
    negative regulation of apoptotic process GO:0043066 ISS
    positive regulation of neutrophil differentiation GO:0045660 IBA
    positive regulation of neutrophil differentiation GO:0045660 ISS
    regulation of cell cycle GO:0051726 ISS
    myeloid cell development GO:0061515 ISS
    regulation of stem cell division GO:2000035 IBA
    regulation of stem cell division GO:2000035 ISS
Subcellular Localization
    plasma membrane GO:0005886 TAS
 Experiment description of studies that identified EVI2B in exosomes
1
Experiment ID 80
MISEV standards
Biophysical techniques
CD81|MHCII
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
2
Experiment ID 81
MISEV standards
Biophysical techniques
CD81|MHCII
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
 Protein-protein interactions for EVI2B
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CDIPT 10423
Two-hybrid Homo sapiens
2 TMEM60  
Two-hybrid Homo sapiens
3 NINJ2  
Two-hybrid Homo sapiens
4 TMEM107 84314
Two-hybrid Homo sapiens
5 SLC30A2  
Two-hybrid Homo sapiens
6 PGRMC1 10857
Two-hybrid Homo sapiens
7 RTP2  
Two-hybrid Homo sapiens
8 AQP1 358
Two-hybrid Homo sapiens
9 FAM3C 10447
Two-hybrid Homo sapiens
10 VAMP4 8674
Two-hybrid Homo sapiens
11 TUSC3 7991
Affinity Capture-MS Homo sapiens
12 SCAMP4 113178
Two-hybrid Homo sapiens
13 NSG1  
Two-hybrid Homo sapiens
14 BTN2A2  
Two-hybrid Homo sapiens
15 AQP3  
Two-hybrid Homo sapiens
16 FUNDC2 65991
Two-hybrid Homo sapiens
17 SLC38A7 55238
Two-hybrid Homo sapiens
18 APOD 347
Two-hybrid Homo sapiens
19 TMEM86B  
Two-hybrid Homo sapiens
20 MYADML2  
Two-hybrid Homo sapiens
21 TMEM222 84065
Two-hybrid Homo sapiens
22 SLC2A5 6518
Two-hybrid Homo sapiens
23 GALNT15  
Two-hybrid Homo sapiens
24 DRAM1  
Two-hybrid Homo sapiens
25 UBIAD1 29914
Two-hybrid Homo sapiens
26 GIMAP5  
Two-hybrid Homo sapiens
27 CLN6  
Two-hybrid Homo sapiens
28 TRAM1L1  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which EVI2B is involved
No pathways found





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