Gene description for ABI3
Gene name ABI family, member 3
Gene symbol ABI3
Other names/aliases NESH
Species Homo sapiens
 Database cross references - ABI3
ExoCarta ExoCarta_51225
Entrez Gene 51225
HGNC 29859
MIM 606363
UniProt Q9P2A4  
 ABI3 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for ABI3
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    regulation of cell migration GO:0030334 IDA
    peptidyl-tyrosine phosphorylation GO:0018108 IDA
    movement of cell or subcellular component GO:0006928 NAS
Subcellular Localization
    intracellular GO:0005622 IDA
    lamellipodium GO:0030027 IDA
    membrane GO:0016020 IDA
    cytoplasm GO:0005737 NAS
 Experiment description of studies that identified ABI3 in exosomes
Experiment ID 217
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ABI3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ABI3BP 25890
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
2 KIAA0408  
Two-hybrid Homo sapiens
3 PAK1  
Reconstituted Complex Homo sapiens
4 KRT15 3866
Two-hybrid Homo sapiens
5 RUNX1T1  
Two-hybrid Homo sapiens
6 DTNBP1  
Two-hybrid Homo sapiens
7 EIF3H 8667
Two-hybrid Homo sapiens
8 CEP170L  
Two-hybrid Homo sapiens
9 SNAP23 8773
Two-hybrid Homo sapiens
10 PAK2 5062
Reconstituted Complex Homo sapiens
11 NIFIE14  
Two-hybrid Homo sapiens
12 KIAA1712  
Two-hybrid Homo sapiens
13 HOMER1  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which ABI3 is involved
No pathways found

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