Gene description for CD209
Gene name CD209 molecule
Gene symbol CD209
Other names/aliases CDSIGN
Species Homo sapiens
 Database cross references - CD209
ExoCarta ExoCarta_30835
Entrez Gene 30835
HGNC 1641
MIM 604672
UniProt Q9NNX6  
 CD209 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for CD209
Molecular Function
    protein binding GO:0005515 IPI
    carbohydrate binding GO:0030246 NAS
    virion binding GO:0046790 TAS
    metal ion binding GO:0046872 IEA
    peptide antigen binding GO:0042605 NAS
    mannose binding GO:0005537 TAS
Biological Process
    heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules GO:0007157 TAS
    endocytosis GO:0006897 IEA
    innate immune response GO:0045087 TAS
    cell-cell recognition GO:0009988 TAS
    antigen processing and presentation GO:0019882 NAS
    regulation of T cell proliferation GO:0042129 IDA
    modulation by virus of host morphology or physiology GO:0019048 TAS
    peptide antigen transport GO:0046968 NAS
    intracellular transport of virus GO:0075733 TAS
    intracellular signal transduction GO:0035556 NAS
    virion attachment to host cell GO:0019062 TAS
    viral genome replication GO:0019079 NAS
    stimulatory C-type lectin receptor signaling pathway GO:0002223 TAS
    leukocyte cell-cell adhesion GO:0007159 NAS
Subcellular Localization
    cytoplasm GO:0005737 NAS
    cell surface GO:0009986 IDA
    extracellular exosome GO:0070062 IDA
    plasma membrane GO:0005886 TAS
    membrane GO:0016020 TAS
    integral component of membrane GO:0016021 IEA
 Experiment description of studies that identified CD209 in exosomes
Experiment ID 217
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for CD209
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CLEC4M  
Invitro Homo sapiens
2 CD209 30835
Invitro Homo sapiens
Invitro Homo sapiens
View the network image/svg+xml
 Pathways in which CD209 is involved
CD209 (DC-SIGN) signaling TAS Reactome

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