Gene description for CTBP1
Gene name C-terminal binding protein 1
Gene symbol CTBP1
Other names/aliases BARS
Species Homo sapiens
 Database cross references - CTBP1
ExoCarta ExoCarta_1487
Vesiclepedia VP_1487
Entrez Gene 1487
HGNC 2494
MIM 602618
UniProt Q13363  
 CTBP1 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Colorectal cancer cells 34887515    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Hepatocellular carcinoma cells 26054723    
Mesenchymal stem cells 36408942    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Thymus 23844026    
 Gene ontology annotations for CTBP1
Molecular Function
    transcription coregulator binding GO:0001221 IBA
    transcription corepressor binding GO:0001222 IPI
    chromatin binding GO:0003682 IEA
    transcription coactivator activity GO:0003713 IBA
    transcription corepressor activity GO:0003714 IBA
    transcription corepressor activity GO:0003714 IDA
    protein binding GO:0005515 IPI
    oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0016616 IEA
    protein domain specific binding GO:0019904 IDA
    protein domain specific binding GO:0019904 IPI
    identical protein binding GO:0042802 IPI
    NAD binding GO:0051287 ISS
    RNA polymerase II-specific DNA-binding transcription factor binding GO:0061629 IEA
    DNA-binding transcription factor binding GO:0140297 IBA
    DNA-binding transcription factor binding GO:0140297 IPI
Biological Process
    negative regulation of transcription by RNA polymerase II GO:0000122 IMP
    regulation of transcription by RNA polymerase II GO:0006357 IBA
    protein phosphorylation GO:0006468 TAS
    negative regulation of cell population proliferation GO:0008285 TAS
    viral genome replication GO:0019079 TAS
    negative regulation of DNA-templated transcription GO:0045892 ISS
    positive regulation of DNA-templated transcription GO:0045893 IEA
    synaptic vesicle endocytosis GO:0048488 IEA
    white fat cell differentiation GO:0050872 ISS
    regulation of cell cycle GO:0051726 IMP
    synaptic vesicle clustering GO:0097091 IEA
Subcellular Localization
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IDA
    nucleus GO:0005634 ISS
    nucleoplasm GO:0005654 IDA
    nucleoplasm GO:0005654 TAS
    transcription repressor complex GO:0017053 IDA
    transcription repressor complex GO:0017053 ISS
    presynaptic active zone cytoplasmic component GO:0098831 IEA
    glutamatergic synapse GO:0098978 IEA
    GABA-ergic synapse GO:0098982 IEA
 Experiment description of studies that identified CTBP1 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
6
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
7
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
9
Experiment ID 235
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
10
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
11
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
12
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for CTBP1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 UBE2H 7328
Affinity Capture-MS Homo sapiens
2 C15orf39  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
3 HIST2H2BE 8349
Affinity Capture-MS Homo sapiens
4 PRKAA1 5562
Two-hybrid Homo sapiens
5 TSHZ1 10194
Proximity Label-MS Homo sapiens
6 HDAC4  
Reconstituted Complex Homo sapiens
7 PCGF5  
Affinity Capture-MS Homo sapiens
8 RBL1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 HDAC2 3066
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
10 ORC4  
Two-hybrid Homo sapiens
11 Fkbp3  
Two-hybrid Mus musculus
12 RBM22 55696
Two-hybrid Homo sapiens
13 PKP2 5318
Two-hybrid Homo sapiens
14 CTBP2 1488
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
15 ZNF518A 9849
Proximity Label-MS Homo sapiens
16 SP1  
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
17 NFATC1 4772
Affinity Capture-MS Homo sapiens
18 ALB 213
Affinity Capture-MS Homo sapiens
19 APC  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
20 FBXL19  
Affinity Capture-MS Homo sapiens
21 BRCA1 672
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
22 TCF7L2  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
23 IGFBP1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
24 CSNK2A1 1457
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
25 IKZF4  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
26 CCDC9  
Two-hybrid Homo sapiens
27 UNKL  
Two-hybrid Homo sapiens
28 RREB1 6239
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
29 SOX2  
Affinity Capture-MS Homo sapiens
30 KCNIP3  
Affinity Capture-Western Homo sapiens
31 TOR2A 27433
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
32 THAP11 57215
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
33 KIAA1429 25962
Affinity Capture-MS Homo sapiens
34 EIF4ENIF1 56478
Affinity Capture-MS Homo sapiens
35 CHD4 1108
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
36 HDAC3 8841
Reconstituted Complex Homo sapiens
37 INA 9118
Affinity Capture-MS Homo sapiens
38 DYRK1A 1859
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
39 TGFB1 7040
Affinity Capture-MS Homo sapiens
40 KLF8  
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
41 FBRSL1  
Proximity Label-MS Homo sapiens
42 HELZ 9931
Affinity Capture-MS Homo sapiens
43 PHC3  
Proximity Label-MS Homo sapiens
44 RGPD6  
Proximity Label-MS Homo sapiens
45 CPSF7 79869
Two-hybrid Homo sapiens
46 NOL4L  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
47 NCOR2  
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
48 RBBP4 5928
Affinity Capture-MS Homo sapiens
49 HIST3H3 8290
Biochemical Activity Homo sapiens
50 CTH 1491
Co-fractionation Homo sapiens
51 ZBTB18  
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
52 C2orf44  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
53 SERPINH1 871
Affinity Capture-Western Homo sapiens
54 BCORL1  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
55 PRR12 57479
Proximity Label-MS Homo sapiens
56 Nono 53610
Two-hybrid Mus musculus
57 ZNF518B  
Proximity Label-MS Homo sapiens
58 KLF4  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
59 ZNF219  
Two-hybrid Homo sapiens
60 YEATS2  
Proximity Label-MS Homo sapiens
61 WDR1 9948
Co-fractionation Homo sapiens
62 Nrip1  
Reconstituted Complex Mus musculus
Affinity Capture-Western Mus musculus
Two-hybrid Mus musculus
63 MRPS7 51081
Affinity Capture-MS Homo sapiens
64 WIZ 58525
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
65 MECP2 4204
Affinity Capture-MS Homo sapiens
66 PRTN3 5657
Affinity Capture-MS Homo sapiens
67 FOXP2 93986
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
68 ARNT2  
Two-hybrid Homo sapiens
69 CSNK2B 1460
Affinity Capture-MS Homo sapiens
70 ADSS 159
Co-fractionation Homo sapiens
71 RCOR3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
72 ZMYM1 79830
Proximity Label-MS Homo sapiens
73 RBM14 10432
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
74 ZFPM2  
Proximity Label-MS Homo sapiens
75 FOXP1 27086
Affinity Capture-Western Homo sapiens
76 DMRTB1  
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
77 Cstf2t  
Two-hybrid Mus musculus
78 RB1 5925
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
79 ZNF217 7764
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
80 PRPF6 24148
Two-hybrid Homo sapiens
81 IKZF2 22807
Two-hybrid Homo sapiens
82 C10orf12  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
83 FOXC1  
Affinity Capture-MS Homo sapiens
84 NME2 4831
Two-hybrid Homo sapiens
85 PCLO 27445
Proximity Label-MS Homo sapiens
86 CDC23 8697
Two-hybrid Homo sapiens
87 CUL3 8452
Affinity Capture-MS Homo sapiens
88 MARCH10  
Two-hybrid Homo sapiens
89 CUL4B 8450
Affinity Capture-Western Homo sapiens
90 PARK2  
Affinity Capture-MS Homo sapiens
91 DUT 1854
Co-fractionation Homo sapiens
92 CTBP1 1487
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
93 HIC1  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
94 PAN2  
Affinity Capture-MS Homo sapiens
95 RBM4B  
Proximity Label-MS Homo sapiens
96 FBXO11  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
97 PNN 5411
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
98 FUNDC1  
Two-hybrid Homo sapiens
99 HTT 3064
Affinity Capture-Western Homo sapiens
100 CEP68 23177
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
101 UBE2I 7329
Affinity Capture-Western Homo sapiens
102 ZEB2  
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
103 CARM1 10498
Co-fractionation Homo sapiens
104 AMPD2 271
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
105 MTMR7  
Affinity Capture-MS Homo sapiens
106 NTRK1 4914
Affinity Capture-MS Homo sapiens
107 FOXK2  
Proximity Label-MS Homo sapiens
108 DCAF7 10238
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
109 PIAS2  
Two-hybrid Homo sapiens
110 DTX2 113878
Proximity Label-MS Homo sapiens
111 PLK1 5347
Affinity Capture-Western Homo sapiens
112 HEMGN  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
113 PRDM16 63976
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
114 SNRPN 6638
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
115 CRY2  
Two-hybrid Homo sapiens
116 BCL6  
Reconstituted Complex Homo sapiens
Co-localization Homo sapiens
Affinity Capture-Western Homo sapiens
117 SOWAHA  
Affinity Capture-MS Homo sapiens
118 NOL4  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
119 CREBBP  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Proximity Label-MS Homo sapiens
120 RBBP8  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
121 Ube2i  
Two-hybrid Mus musculus
122 HDAC5 10014
Reconstituted Complex Homo sapiens
123 KLF12  
Proximity Label-MS Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
124 BCOR  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
125 KIAA1551  
Proximity Label-MS Homo sapiens
126 CD274 29126
Affinity Capture-MS Homo sapiens
127 ZNF516 9658
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
128 KDF1  
Affinity Capture-MS Homo sapiens
129 Nufip2  
Two-hybrid Mus musculus
130 PLCB1 23236
Two-hybrid Homo sapiens
131 BAG3 9531
Affinity Capture-Luminescence Homo sapiens
132 NCKAP5L  
Proximity Label-MS Homo sapiens
133 GATAD2A 54815
Proximity Label-MS Homo sapiens
134 Rbm14  
Two-hybrid Mus musculus
135 SFPQ 6421
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
136 Nudt21 68219
Two-hybrid Mus musculus
137 SF1 7536
Two-hybrid Homo sapiens
138 FANCD2  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
139 KMT2A  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
140 SOX6  
Proximity Label-MS Homo sapiens
141 ECT2 1894
Affinity Capture-MS Homo sapiens
142 ELK3  
Proximity Label-MS Homo sapiens
143 HOXB5  
Two-hybrid Homo sapiens
144 AKAP9 10142
Two-hybrid Homo sapiens
145 CTNNB1 1499
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
146 BCAS3 54828
Two-hybrid Homo sapiens
147 LCOR 84458
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
148 SLC35F2 54733
Affinity Capture-MS Homo sapiens
149 HDAC9  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
150 DOK4 55715
Affinity Capture-MS Homo sapiens
151 TFAP4 7023
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
152 EGFR 1956
Affinity Capture-MS Homo sapiens
153 E2F7  
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
154 BCL3  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
155 EP400  
Proximity Label-MS Homo sapiens
156 IKZF1  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
157 ECHS1 1892
Co-fractionation Homo sapiens
158 Kif18a  
Two-hybrid Mus musculus
159 KIAA0430  
Affinity Capture-MS Homo sapiens
160 HYI 81888
Co-fractionation Homo sapiens
161 FANCE  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
162 PRKCI 5584
Two-hybrid Homo sapiens
163 FANCA  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
164 EPHA2 1969
Proximity Label-MS Homo sapiens
165 Dusp14  
Two-hybrid Mus musculus
166 PRPF19 27339
Two-hybrid Homo sapiens
167 SPEN 23013
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
168 SERBP1 26135
Affinity Capture-MS Homo sapiens
169 SSNA1 8636
Co-fractionation Homo sapiens
170 RBM14-RBM4 100526737
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
171 RBL2 5934
Affinity Capture-Western Homo sapiens
172 CSNK2A2 1459
Affinity Capture-MS Homo sapiens
173 CHD3 1107
Two-hybrid Homo sapiens
174 DGCR6  
Two-hybrid Homo sapiens
175 EHMT2 10919
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
176 HSPA1A 3303
Co-fractionation Homo sapiens
177 TBL1X 6907
Affinity Capture-Western Homo sapiens
178 SART3 9733
Two-hybrid Homo sapiens
179 FBRS 64319
Proximity Label-MS Homo sapiens
180 ACTL6B  
Phenotypic Enhancement Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
181 SMAD6  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
182 TERF2IP 54386
Two-hybrid Homo sapiens
183 CTNNA1 1495
Two-hybrid Homo sapiens
184 MECOM 2122
Phenotypic Enhancement Homo sapiens
Phenotypic Suppression Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
185 AKT1 207
Affinity Capture-Western Homo sapiens
186 CCND1 595
Co-fractionation Homo sapiens
187 RBBP5 5929
Two-hybrid Homo sapiens
188 NFATC2  
Affinity Capture-MS Homo sapiens
189 KDM2B 84678
Proximity Label-MS Homo sapiens
190 MDM2  
Far Western Homo sapiens
Affinity Capture-Western Homo sapiens
191 TRPS1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
192 Pcbp1 23983
Two-hybrid Mus musculus
193 ATIC 471
Co-fractionation Homo sapiens
194 SATB1 6304
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
195 H2AFX 3014
Two-hybrid Homo sapiens
196 CBX4  
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
197 RAI2  
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
198 DZIP3  
Affinity Capture-MS Homo sapiens
199 GFI1B  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
200 PRDM2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
201 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
202 TERF2  
Two-hybrid Homo sapiens
203 TP53 7157
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
204 KAT2A  
Affinity Capture-Western Homo sapiens
205 TSHZ3  
Two-hybrid Homo sapiens
Proximity Label-MS Homo sapiens
206 FANCC 2176
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
207 LCORL  
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
208 TUBG1 7283
Affinity Capture-Western Homo sapiens
209 SEC16A 9919
Proximity Label-MS Homo sapiens
210 TBP  
Reconstituted Complex Homo sapiens
211 ZEB1  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
212 ATXN1L  
Two-hybrid Homo sapiens
213 KAT2B  
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
214 FANCL 55120
Two-hybrid Homo sapiens
215 FANCG 2189
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
216 KLF3  
Proximity Label-MS Homo sapiens
Two-hybrid Homo sapiens
217 TRMT61B  
Affinity Capture-MS Homo sapiens
218 ZBP1  
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
219 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
220 DCAF11  
Affinity Capture-MS Homo sapiens
221 HDAC1 3065
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
222 E2F4  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
223 NISCH 11188
Affinity Capture-MS Homo sapiens
224 CEP76  
Affinity Capture-MS Homo sapiens
225 FKBP1A 2280
Co-fractionation Homo sapiens
226 CDYL 9425
Affinity Capture-Western Homo sapiens
227 PRRC2B  
Two-hybrid Homo sapiens
228 GTF2B 2959
Reconstituted Complex Homo sapiens
229 CREB5 9586
Affinity Capture-MS Homo sapiens
230 ESR1  
Affinity Capture-MS Homo sapiens
231 TGIF1  
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
232 FOXK1 221937
Affinity Capture-MS Homo sapiens
233 RCOR2 283248
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
234 KDM1A 23028
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
235 TCF4  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
236 GAPDH 2597
Co-fractionation Homo sapiens
237 HIC2 23119
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
238 MAPK9 5601
Two-hybrid Homo sapiens
239 FANCF  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
240 RNF111 54778
Two-hybrid Homo sapiens
241 HSD11B2  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
242 NRIP1 8204
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Proximity Label-MS Homo sapiens
243 EHMT1  
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
244 SNW1 22938
Two-hybrid Homo sapiens
245 C9orf72  
Affinity Capture-MS Homo sapiens
246 SOBP  
Two-hybrid Homo sapiens
247 ZBTB42  
Affinity Capture-MS Homo sapiens
248 GNL3L 54552
Two-hybrid Homo sapiens
249 SERPINA4 5267
Affinity Capture-MS Homo sapiens
250 Pspc1  
Two-hybrid Mus musculus
251 MED15  
Proximity Label-MS Homo sapiens
252 RCOR1  
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
253 LNX1  
Two-hybrid Homo sapiens
254 EP300 2033
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
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Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here