Gene description for Ap1b1
Gene name adaptor protein complex AP-1, beta 1 subunit
Gene symbol Ap1b1
Other names/aliases Adtb1
b2b1660Clo
Species Mus musculus
 Database cross references - Ap1b1
ExoCarta ExoCarta_11764
Entrez Gene 11764
UniProt O35643  
 Ap1b1 identified in exosomes derived from the following tissue/cell type
Pancreatic cells 19351151    
 Gene ontology annotations for Ap1b1
Molecular Function
    protein binding GO:0005515 IPI
    protein transporter activity GO:0008565 IEA
    protein kinase binding GO:0019901 IPI
Biological Process
    protein transport GO:0015031 IEA
    intracellular protein transport GO:0006886 TAS
    vesicle-mediated transport GO:0016192 TAS
    transport GO:0006810 IEA
    clathrin coat assembly GO:0048268 ISO
Subcellular Localization
    membrane GO:0016020 IEA
    cytoplasmic vesicle GO:0031410 IEA
    membrane coat GO:0030117 IEA
    clathrin adaptor complex GO:0030131 IEA
    trans-Golgi network GO:0005802 TAS
    Golgi apparatus GO:0005794 IEA
 Experiment description of studies that identified Ap1b1 in exosomes
1
Experiment ID 188
ISEV standards
✔
EM
EV Biophysical techniques
✔
GAPDH|UCHL1|HSP90
EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors Lee HS, Jeong J, Lee KJ.
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Ap1b1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ATM  
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
View the network image/svg+xml



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