Gene description for ABHD16A
Gene name abhydrolase domain containing 16A
Gene symbol ABHD16A
Other names/aliases BAT5
D6S82E
NG26
PP199
Species Homo sapiens
 Database cross references - ABHD16A
ExoCarta ExoCarta_7920
Vesiclepedia VP_7920
Entrez Gene 7920
HGNC 13921
MIM 142620
UniProt O95870  
 ABHD16A identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Platelets 25332113    
Platelets 25332113    
Platelets 25332113    
 Gene ontology annotations for ABHD16A
Molecular Function
    phospholipase activity GO:0004620 IBA
    phospholipase activity GO:0004620 ISS
    lysophospholipase activity GO:0004622 IDA
    protein binding GO:0005515 IPI
    monoacylglycerol lipase activity GO:0047372 IBA
    monoacylglycerol lipase activity GO:0047372 IDA
Biological Process
    phosphatidylserine catabolic process GO:0006660 IBA
    phosphatidylserine catabolic process GO:0006660 ISS
    monoacylglycerol catabolic process GO:0052651 IBA
    monoacylglycerol catabolic process GO:0052651 IDA
    prostaglandin catabolic process GO:1905344 IDA
Subcellular Localization
    membrane GO:0016020 IEA
 Experiment description of studies that identified ABHD16A in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 231
MISEV standards
✘ Biophysical techniques
✔
Alix|CD63|CD9
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Western blotting
Mass spectrometry
6
Experiment ID 232
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
7
Experiment ID 233
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ABHD16A
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SEC22B 9554
Two-hybrid Homo sapiens
2 WBP1L  
Two-hybrid Homo sapiens
3 PRAF2 11230
Two-hybrid Homo sapiens
4 GJA5 2702
Two-hybrid Homo sapiens
5 BSCL2  
Affinity Capture-MS Homo sapiens
6 PKMYT1  
Two-hybrid Homo sapiens
7 ATP5J 522
Two-hybrid Homo sapiens
8 CMTM5  
Affinity Capture-MS Homo sapiens
9 SLC30A2  
Two-hybrid Homo sapiens
10 KCNA2  
Affinity Capture-MS Homo sapiens
11 GOLT1A  
Two-hybrid Homo sapiens
12 ITGAM 3684
Two-hybrid Homo sapiens
13 POLE  
Two-hybrid Homo sapiens
14 TMEM143  
Two-hybrid Homo sapiens
15 CYP1A2  
Two-hybrid Homo sapiens
16 TBC1D9  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 TM4SF19  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
18 SLC10A1  
Two-hybrid Homo sapiens
19 MCOLN3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
20 RAB43 339122
Affinity Capture-MS Homo sapiens
21 TMEM147 10430
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
22 HTR3C  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
23 IGHM 3507
Affinity Capture-MS Homo sapiens
24 ERGIC3 51614
Two-hybrid Homo sapiens
25 TMEM14B  
Two-hybrid Homo sapiens
26 RICTOR 253260
Affinity Capture-MS Homo sapiens
27 Csde1 229663
Affinity Capture-MS Mus musculus
28 HM13 81502
Two-hybrid Homo sapiens
29 MLH1 4292
Two-hybrid Homo sapiens
30 IFITM3 10410
Two-hybrid Homo sapiens
31 HSD17B13  
Two-hybrid Homo sapiens
32 AGPAT3 56894
Two-hybrid Homo sapiens
33 SLC31A2  
Affinity Capture-MS Homo sapiens
34 IFITM1 8519
Two-hybrid Homo sapiens
35 GDAP1 54332
Two-hybrid Homo sapiens
36 NXF1 10482
Affinity Capture-RNA Homo sapiens
37 TSPAN2 10100
Two-hybrid Homo sapiens
38 GORAB 92344
Two-hybrid Homo sapiens
39 TMEM139  
Two-hybrid Homo sapiens
40 SAAL1 113174
Affinity Capture-MS Homo sapiens
41 EBP  
Two-hybrid Homo sapiens
42 SPAG7  
Two-hybrid Homo sapiens
43 GPR152  
Two-hybrid Homo sapiens
44 FAM134C 162427
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
45 BRI3 25798
Two-hybrid Homo sapiens
46 RNF5  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
47 VAMP5 10791
Two-hybrid Homo sapiens
48 FAM69A 388650
Affinity Capture-MS Homo sapiens
49 TMEM65 157378
Two-hybrid Homo sapiens
50 PERP 64065
Two-hybrid Homo sapiens
51 UPF1 5976
Two-hybrid Homo sapiens
52 TMEM222 84065
Two-hybrid Homo sapiens
53 UNC93A  
Two-hybrid Homo sapiens
54 DTX2 113878
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
55 SERF1B  
Two-hybrid Homo sapiens
56 RHBDL1  
Two-hybrid Homo sapiens
57 CREB3  
Two-hybrid Homo sapiens
58 TMEM237 65062
Two-hybrid Homo sapiens
59 DNAJC1 64215
Two-hybrid Homo sapiens
60 SAFB 6294
Two-hybrid Homo sapiens
61 SCNN1D  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
62 VMA21  
Two-hybrid Homo sapiens
63 ATP5G3 518
Two-hybrid Homo sapiens
64 CIDEB  
Two-hybrid Homo sapiens
65 AQP7  
Two-hybrid Homo sapiens
66 GPRC5C 55890
Two-hybrid Homo sapiens
67 LTA  
Two-hybrid Homo sapiens
68 GYPC 2995
Two-hybrid Homo sapiens
69 FDPS 2224
Two-hybrid Homo sapiens
70 SERF1A  
Two-hybrid Homo sapiens
71 TMEM31  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which ABHD16A is involved
No pathways found





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