Gene description for TSHZ1
Gene name teashirt zinc finger homeobox 1
Gene symbol TSHZ1
Other names/aliases CAA
NY-CO-33
SDCCAG33
TSH1
Species Homo sapiens
 Database cross references - TSHZ1
ExoCarta ExoCarta_10194
Vesiclepedia VP_10194
Entrez Gene 10194
HGNC 10669
MIM 614427
UniProt Q6ZSZ6  
 TSHZ1 identified in sEVs derived from the following tissue/cell type
Neuroblastoma cells 25944692    
 Gene ontology annotations for TSHZ1
Molecular Function
    DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 IBA
    DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 ISA
    DNA binding GO:0003677 IBA
    metal ion binding GO:0046872 IEA
Biological Process
    regulation of transcription by RNA polymerase II GO:0006357 IBA
    anterior/posterior pattern specification GO:0009952 IEA
    middle ear morphogenesis GO:0042474 IEA
    soft palate development GO:0060023 IEA
Subcellular Localization
    chromatin GO:0000785 ISA
    nucleus GO:0005634 IBA
 Experiment description of studies that identified TSHZ1 in sEVs
1
Experiment ID 224
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for TSHZ1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 FOXJ2  
Affinity Capture-MS Homo sapiens
2 TSHZ2  
Affinity Capture-MS Homo sapiens
3 MEIS2  
Affinity Capture-MS Homo sapiens
4 HSP90AB1 3326
Cross-Linking-MS (XL-MS) Homo sapiens
5 RPL26 6154
Cross-Linking-MS (XL-MS) Homo sapiens
6 TSHZ3  
Affinity Capture-MS Homo sapiens
7 CTBP1 1487
Proximity Label-MS Homo sapiens
8 APBB1  
Reconstituted Complex Homo sapiens
9 PBX3  
Affinity Capture-MS Homo sapiens
10 RBBP4 5928
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which TSHZ1 is involved
No pathways found





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