Gene description for CD226
Gene name	CD226 molecule
Gene symbol	CD226
Other names/aliases	DNAM-1 DNAM1 PTA1 TLiSA1
Species	Homo sapiens
Database cross references - CD226
ExoCarta	ExoCarta_10666
Vesiclepedia	VP_10666
Entrez Gene	10666
HGNC	16961
MIM	605397
UniProt	Q15762
CD226 identified in sEVs derived from the following tissue/cell type
Platelets	25332113
Platelets	25332113
Platelets	25332113

Gene ontology annotations for CD226

Molecular Function     integrin binding GO:0005178 IPI     protein binding GO:0005515 IPI     protein kinase binding GO:0019901 IPI     signaling receptor activity GO:0038023 IDA     identical protein binding GO:0042802 IPI     cell adhesion molecule binding GO:0050839 IBA     cell adhesion molecule binding GO:0050839 IPI Biological Process     positive regulation of natural killer cell cytokine production GO:0002729 IEA     positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002860 IMP     positive regulation of immunoglobulin mediated immune response GO:0002891 IBA     positive regulation of immunoglobulin mediated immune response GO:0002891 IDA     cell adhesion GO:0007155 IEA     signal transduction GO:0007165 TAS     cell recognition GO:0008037 TAS     positive regulation of type II interferon production GO:0032729 IEA     positive regulation of mast cell activation GO:0033005 IDA     natural killer cell mediated cytotoxicity GO:0042267 IDA     positive regulation of natural killer cell mediated cytotoxicity GO:0045954 IMP     positive regulation of T cell receptor signaling pathway GO:0050862 IBA     positive regulation of T cell receptor signaling pathway GO:0050862 IMP     positive regulation of Fc receptor mediated stimulatory signaling pathway GO:0060369 IBA     positive regulation of Fc receptor mediated stimulatory signaling pathway GO:0060369 IDA Subcellular Localization     plasma membrane GO:0005886 IC     plasma membrane GO:0005886 TAS     external side of plasma membrane GO:0009897 IBA     cell surface GO:0009986 IDA     membrane raft GO:0045121 TAS