Gene description for QSOX2
Gene name quiescin Q6 sulfhydryl oxidase 2
Gene symbol QSOX2
Other names/aliases QSCN6L1
SOXN
Species Homo sapiens
 Database cross references - QSOX2
ExoCarta ExoCarta_169714
Entrez Gene 169714
HGNC 30249
MIM 612860
UniProt Q6ZRP7  
 QSOX2 identified in exosomes derived from the following tissue/cell type
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
 Gene ontology annotations for QSOX2
Molecular Function
    flavin-linked sulfhydryl oxidase activity GO:0016971 IBA
    protein disulfide isomerase activity GO:0003756 IBA
Biological Process
    cell redox homeostasis GO:0045454 IEA
    oxidation-reduction process GO:0055114 IEA
    protein folding GO:0006457 IBA
Subcellular Localization
    nuclear membrane GO:0031965 IEA
    integral component of Golgi membrane GO:0030173 IBA
    extracellular space GO:0005615 IBA
    plasma membrane GO:0005886 IEA
 Experiment description of studies that identified QSOX2 in exosomes
1
Experiment ID 211
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
EpCAM|TFRC
EV Membrane markers
cytochrome c|GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 212
ISEV standards
CEM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
EpCAM|TFRC
EV Membrane markers
Cytochrome C|GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for QSOX2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which QSOX2 is involved
No pathways found





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