Gene description for PTPRK
Gene name protein tyrosine phosphatase, receptor type, K
Gene symbol PTPRK
Other names/aliases R-PTP-kappa
Species Homo sapiens
 Database cross references - PTPRK
ExoCarta ExoCarta_5796
Vesiclepedia VP_5796
Entrez Gene 5796
HGNC 9674
MIM 602545
UniProt Q15262  
 PTPRK identified in exosomes derived from the following tissue/cell type
Colorectal cancer cells 34887515    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Keratinocytes 19530224    
Keratinocytes 19530224    
Mesenchymal stem cells Unpublished / Not applicable
Mesenchymal stem cells 36408942    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
 Gene ontology annotations for PTPRK
Molecular Function
    protein tyrosine phosphatase activity GO:0004725 IBA
    protein tyrosine phosphatase activity GO:0004725 IDA
    non-membrane spanning protein tyrosine phosphatase activity GO:0004726 IEA
    transmembrane receptor protein tyrosine phosphatase activity GO:0005001 NAS
    protein binding GO:0005515 IPI
    beta-catenin binding GO:0008013 IPI
    protein kinase binding GO:0019901 IPI
    protein tyrosine phosphatase activity, metal-dependent GO:0030946 IEA
    gamma-catenin binding GO:0045295 IPI
    histone H2AXY142 phosphatase activity GO:0140793 IEA
Biological Process
    chromatin remodeling GO:0006338 IEA
    protein dephosphorylation GO:0006470 IDA
    cell adhesion GO:0007155 IMP
    signal transduction GO:0007165 IBA
    signal transduction GO:0007165 IDA
    transforming growth factor beta receptor signaling pathway GO:0007179 IDA
    negative regulation of cell population proliferation GO:0008285 IDA
    negative regulation of keratinocyte proliferation GO:0010839 IDA
    cell migration GO:0016477 IMP
    negative regulation of cell migration GO:0030336 IDA
    neuron projection development GO:0031175 IBA
    protein localization to cell surface GO:0034394 IDA
    cellular response to reactive oxygen species GO:0034614 IDA
    cellular response to UV GO:0034644 IDA
    negative regulation of cell cycle GO:0045786 IDA
    negative regulation of DNA-templated transcription GO:0045892 IDA
    focal adhesion assembly GO:0048041 IMP
Subcellular Localization
    plasma membrane GO:0005886 IDA
    plasma membrane GO:0005886 NAS
    cell-cell junction GO:0005911 IDA
    adherens junction GO:0005912 IEA
    cell surface GO:0009986 IDA
    membrane GO:0016020 NAS
    cell junction GO:0030054 IDA
    leading edge membrane GO:0031256 IDA
    intracellular membrane-bounded organelle GO:0043231 IDA
 Experiment description of studies that identified PTPRK in exosomes
1
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
2
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
3
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
4
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
5
Experiment ID 189
MISEV standards
✔
EM
Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19530224    
Organism Homo sapiens
Experiment description Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes.
Authors "Chavez-Muñoz C, Kilani RT, Ghahary A."
Journal name J Cell Physiol
Publication year 2009
Sample Keratinocytes
Sample name Keratinocytes - Differentiated
Isolation/purification methods Differential centrifugation
Filtration
Sucrose cushion
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
6
Experiment ID 190
MISEV standards
✔
EM
Biophysical techniques
✔
HSC70
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19530224    
Organism Homo sapiens
Experiment description Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes.
Authors "Chavez-Muñoz C, Kilani RT, Ghahary A."
Journal name J Cell Physiol
Publication year 2009
Sample Keratinocytes
Sample name Keratinocytes - Undifferentiated
Isolation/purification methods Differential centrifugation
Filtration
Sucrose cushion
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
7
Experiment ID 126
MISEV standards
✘ Biophysical techniques
✔
GAPDH
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
8
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
9
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
10
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
11
Experiment ID 834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for PTPRK
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 DCBLD2 131566
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
2 COL6A1 1291
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 HFE  
Affinity Capture-MS Homo sapiens
4 CSTL1  
Affinity Capture-MS Homo sapiens
5 LGALS12  
Affinity Capture-MS Homo sapiens
6 SPRTN  
Affinity Capture-MS Homo sapiens
7 CEACAM8 1088
Affinity Capture-MS Homo sapiens
8 CACNA2D1 781
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 CHRNA4  
Affinity Capture-MS Homo sapiens
10 TK1 7083
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
11 CD48 962
Affinity Capture-MS Homo sapiens
12 CACNA2D2 9254
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
13 MAN2A1 4124
Affinity Capture-MS Homo sapiens
14 ARSA 410
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
15 PSMD11 5717
Two-hybrid Homo sapiens
16 GADD45A  
Two-hybrid Homo sapiens
17 DEFA5  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
18 PCDHGB4 8641
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 ARSB 411
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
20 LGALS1 3956
Affinity Capture-MS Homo sapiens
21 CES3 23491
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
22 OIT3 170392
Affinity Capture-MS Homo sapiens
23 TMEM67 91147
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
24 ERO1LB 56605
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
25 ZNF3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
26 AMIGO1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
27 RIPK3 11035
Affinity Capture-MS Homo sapiens
28 PLXNA3 55558
Affinity Capture-MS Homo sapiens
29 GLG1 2734
Affinity Capture-MS Homo sapiens
30 ZNF74  
Affinity Capture-MS Homo sapiens
31 NCKAP5L  
Proximity Label-MS Homo sapiens
32 ADAM9 8754
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
33 COL4A2 1284
Affinity Capture-MS Homo sapiens
34 HYAL2 8692
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
35 CD109 135228
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
36 AMIGO3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
37 NXPH1  
Affinity Capture-MS Homo sapiens
38 CNTNAP3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
39 ATP2A3 489
Affinity Capture-MS Homo sapiens
40 CTSF 8722
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
41 SCARB1 949
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
42 PEAK1 79834
Proximity Label-MS Homo sapiens
43 ITGA8 8516
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
44 DGCR2 9993
Affinity Capture-MS Homo sapiens
45 ST8SIA4 7903
Affinity Capture-MS Homo sapiens
46 HYPM  
Affinity Capture-MS Homo sapiens
47 NID2 22795
Affinity Capture-MS Homo sapiens
48 EOGT 285203
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
49 LGALS9 3965
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
50 BTNL2  
Affinity Capture-MS Homo sapiens
51 POGLUT1 56983
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
52 CSNK2B 1460
Two-hybrid Homo sapiens
53 PXDN 7837
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
54 EGFR 1956
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
55 CCDC102A 92922
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
56 MICA 100507436
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
57 CHST12 55501
Affinity Capture-MS Homo sapiens
58 KLK5 25818
Affinity Capture-MS Homo sapiens
59 B3GALTL 145173
Affinity Capture-MS Homo sapiens
60 MOXD1 26002
Affinity Capture-MS Homo sapiens
61 NPC1 4864
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
62 FBLN1 2192
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
63 PCSK5 5125
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
64 GADD45G  
Two-hybrid Homo sapiens
65 SLC39A9 55334
Affinity Capture-MS Homo sapiens
66 MCAM 4162
Proximity Label-MS Homo sapiens
67 TUFM 7284
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
68 MANBA 4126
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
69 TANC1 85461
Proximity Label-MS Homo sapiens
70 MAN2A2 4122
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
71 BCHE 590
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
72 DNAJB9 4189
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
73 TCTN2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
74 FRAS1 80144
Affinity Capture-MS Homo sapiens
75 GRIN1 2902
Affinity Capture-MS Homo sapiens
76 CDHR4  
Affinity Capture-MS Homo sapiens
77 CD160  
Affinity Capture-MS Homo sapiens
78 ITGA4 3676
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
79 GALNS 2588
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
80 LRP1B 53353
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
81 ARL4C 10123
Affinity Capture-MS Homo sapiens
82 SEC61B 10952
Proximity Label-MS Homo sapiens
83 TMPRSS13  
Affinity Capture-MS Homo sapiens
84 CERCAM 51148
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
85 LY86  
Affinity Capture-MS Homo sapiens
86 MEGF8 1954
Affinity Capture-MS Homo sapiens
87 GPIHBP1  
Affinity Capture-MS Homo sapiens
88 MINK1 50488
Proximity Label-MS Homo sapiens
89 PCDHGB1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
90 PLAT 5327
Affinity Capture-MS Homo sapiens
91 SUSD1 64420
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
92 EGLN3  
Affinity Capture-MS Homo sapiens
93 TMPRSS11B 132724
Affinity Capture-MS Homo sapiens
94 CMA1  
Affinity Capture-MS Homo sapiens
95 BTD 686
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
96 CTNNB1 1499
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
97 GNPTG 84572
Affinity Capture-MS Homo sapiens
98 MMP26  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
99 ATRN 8455
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
100 CBLN4  
Affinity Capture-MS Homo sapiens
101 CLEC4A  
Affinity Capture-MS Homo sapiens
102 GRIN2C 2905
Affinity Capture-MS Homo sapiens
103 FKBP8 23770
Affinity Capture-MS Homo sapiens
104 WNT5A 7474
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
105 BMP7 655
Affinity Capture-MS Homo sapiens
106 LGALS7 3963
Affinity Capture-MS Homo sapiens
107 ECE1 1889
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
108 MGRN1 23295
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
109 CLN5  
Affinity Capture-MS Homo sapiens
110 FUT11 170384
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
111 TMEM132A 54972
Affinity Capture-MS Homo sapiens
112 LRIG1 26018
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
113 FBXO2 26232
Affinity Capture-MS Homo sapiens
114 PKP4 8502
Proximity Label-MS Homo sapiens
115 LYPD1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
116 P3H3 10536
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
117 DNASE1L1 1774
Affinity Capture-MS Homo sapiens
118 CST9L  
Affinity Capture-MS Homo sapiens
119 CHST10  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
120 PTPRU  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
121 LGALS8 3964
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
122 PIK3R1 5295
Proximity Label-MS Homo sapiens
123 LRIG3  
Affinity Capture-MS Homo sapiens
124 SEC24B 10427
Proximity Label-MS Homo sapiens
125 LAMB1 3912
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
126 PLXNB2 23654
Affinity Capture-MS Homo sapiens
127 PLXNA2 5362
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
128 SIAE 54414
Affinity Capture-MS Homo sapiens
129 JUP 3728
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
130 LGALS3 3958
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
131 PLXNA1 5361
Affinity Capture-MS Homo sapiens
132 SIPA1L3  
Proximity Label-MS Homo sapiens
133 RYK 6259
Affinity Capture-MS Homo sapiens
134 INSR 3643
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
135 UBR3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
136 ATP2A2 488
Affinity Capture-MS Homo sapiens
137 ARHGAP32  
Proximity Label-MS Homo sapiens
138 COL6A2 1292
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
139 GALNT18  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
140 ARSG 22901
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
141 LAMB2 3913
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
142 LAMA5 3911
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
143 RPL28 6158
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
144 EVA1B 55194
Affinity Capture-MS Homo sapiens
145 ANKRD46 157567
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
146 ARSK  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
147 SCARB2 950
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
148 LAMA3 3909
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
149 SP3  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which PTPRK is involved
PathwayEvidenceSource
EGFR downregulation TAS Reactome
Signal Transduction TAS Reactome
Signaling by EGFR TAS Reactome
Signaling by Receptor Tyrosine Kinases TAS Reactome





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