Gene description for ANKHD1
Gene name ankyrin repeat and KH domain containing 1
Gene symbol ANKHD1
Other names/aliases MASK
MASK1
PP2500
VBARP
Species Homo sapiens
 Database cross references - ANKHD1
ExoCarta ExoCarta_54882
Vesiclepedia VP_54882
Entrez Gene 54882
HGNC 24714
MIM 610500
UniProt Q8IWZ3  
 ANKHD1 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Mesenchymal stem cells 36408942    
 Gene ontology annotations for ANKHD1
Molecular Function
    RNA binding GO:0003723 HDA
    protein binding GO:0005515 IPI
Biological Process
    innate immune response GO:0045087 IBA
Subcellular Localization
    cytoplasm GO:0005737 IBA
 Experiment description of studies that identified ANKHD1 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for ANKHD1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 VARS 7407
Co-fractionation Homo sapiens
2 RBPMS 11030
Two-hybrid Homo sapiens
3 ZNF346  
Two-hybrid Homo sapiens
4 HOXA7  
Affinity Capture-MS Homo sapiens
5 S100A6 6277
Affinity Capture-MS Homo sapiens
6 QKI 9444
Two-hybrid Homo sapiens
7 EPB41L5 57669
Affinity Capture-MS Homo sapiens
8 MAGEA1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 ARF3 377
Affinity Capture-MS Homo sapiens
10 UBC 7316
Reconstituted Complex Homo sapiens
11 ZNF433  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
12 CAND1 55832
Affinity Capture-MS Homo sapiens
13 FGF3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
14 DBX2  
Affinity Capture-MS Homo sapiens
15 STX11 8676
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
16 ZNF414  
Affinity Capture-MS Homo sapiens
17 HOXB6 3216
Affinity Capture-MS Homo sapiens
18 EIF4ENIF1 56478
Two-hybrid Homo sapiens
19 AKAP17A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
20 MEAF6  
Affinity Capture-MS Homo sapiens
21 DYRK1A 1859
Affinity Capture-MS Homo sapiens
22 C9orf85  
Affinity Capture-MS Homo sapiens
23 HOXA5  
Affinity Capture-MS Homo sapiens
24 D2HGDH 728294
Affinity Capture-MS Homo sapiens
25 RFXANK  
Affinity Capture-MS Homo sapiens
26 CERKL  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
27 RPLP1 6176
Co-fractionation Homo sapiens
28 FBXW7  
Affinity Capture-MS Homo sapiens
29 KLF6  
Affinity Capture-MS Homo sapiens
30 RECQL4  
Affinity Capture-MS Homo sapiens
31 FGF17  
Affinity Capture-MS Homo sapiens
32 DDOST 1650
Affinity Capture-MS Homo sapiens
33 PRRC2B  
Two-hybrid Homo sapiens
34 EIF3E 3646
Two-hybrid Homo sapiens
35 TULP3 7289
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
36 CDT1  
Affinity Capture-MS Homo sapiens
37 KRTAP19-5  
Two-hybrid Homo sapiens
38 IL17RA 23765
Affinity Capture-MS Homo sapiens
39 POLR2M  
Two-hybrid Homo sapiens
40 ADARB2  
Affinity Capture-MS Homo sapiens
41 RBFOX2 23543
Two-hybrid Homo sapiens
42 PRR20C  
Two-hybrid Homo sapiens
43 PRR20A  
Two-hybrid Homo sapiens
44 FAS 355
Proximity Label-MS Homo sapiens
45 DMRTB1  
Two-hybrid Homo sapiens
46 CPEB1  
Proximity Label-MS Homo sapiens
47 PFN1 5216
Proximity Label-MS Homo sapiens
48 BAG5 9529
Affinity Capture-MS Homo sapiens
49 TRIM41 90933
Affinity Capture-MS Homo sapiens
50 KLF9 687
Affinity Capture-MS Homo sapiens
51 SULT1C4  
Affinity Capture-MS Homo sapiens
52 KRTAP15-1  
Two-hybrid Homo sapiens
53 PLBD1 79887
Affinity Capture-MS Homo sapiens
54 ANKRD17 26057
Affinity Capture-MS Homo sapiens
55 QPRT 23475
Affinity Capture-MS Homo sapiens
56 PHAX  
Affinity Capture-MS Homo sapiens
57 B4GALT2  
Affinity Capture-MS Homo sapiens
58 RPA4  
Proximity Label-MS Homo sapiens
59 GOLGA2 2801
Two-hybrid Homo sapiens
60 HIST1H2AM 8336
Affinity Capture-MS Homo sapiens
61 VCP 7415
Affinity Capture-MS Homo sapiens
62 SLX4  
Affinity Capture-MS Homo sapiens
63 FGF8  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
64 BAG4  
Two-hybrid Homo sapiens
65 SIX5  
Affinity Capture-MS Homo sapiens
66 DNAJA1 3301
Co-fractionation Homo sapiens
67 CBX6  
Affinity Capture-MS Homo sapiens
68 HUWE1 10075
Affinity Capture-MS Homo sapiens
69 KLF10  
Affinity Capture-MS Homo sapiens
70 NOB1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
71 Pcna 18538
Affinity Capture-MS Mus musculus
72 RPS16 6217
Affinity Capture-MS Homo sapiens
73 ZNF34  
Two-hybrid Homo sapiens
74 TXNL4A 10907
Two-hybrid Homo sapiens
75 CDX1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
76 HIST1H2AB 8335
Affinity Capture-MS Homo sapiens
77 UBXN6 80700
Affinity Capture-MS Homo sapiens
78 USP32 84669
Affinity Capture-MS Homo sapiens
79 SIX2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
80 PPP1R12B 4660
Affinity Capture-MS Homo sapiens
81 PSG11  
Affinity Capture-MS Homo sapiens
82 ATXN1 6310
Two-hybrid Homo sapiens
83 FGFBP1 9982
Affinity Capture-MS Homo sapiens
84 DISC1 27185
Affinity Capture-MS Homo sapiens
85 NFKBIE  
Two-hybrid Homo sapiens
86 HSPA5 3309
Co-fractionation Homo sapiens
87 WHAMMP3  
Affinity Capture-MS Homo sapiens
88 IRF9 10379
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
89 AHCYL1 10768
Co-fractionation Homo sapiens
90 AMBRA1  
Affinity Capture-MS Homo sapiens
91 BAG2 9532
Affinity Capture-MS Homo sapiens
92 SIRT7  
Affinity Capture-MS Homo sapiens
93 PHIP 55023
Affinity Capture-MS Homo sapiens
94 HOXB7 3217
Affinity Capture-MS Homo sapiens
95 PRR20D  
Two-hybrid Homo sapiens
96 METTL21B  
Affinity Capture-MS Homo sapiens
97 FOSL2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
98 HOXD4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
99 NXF1 10482
Affinity Capture-RNA Homo sapiens
100 CRYBB3  
Affinity Capture-MS Homo sapiens
101 MAPK6  
Affinity Capture-MS Homo sapiens
102 LUC7L2 51631
Two-hybrid Homo sapiens
103 C12orf74  
Affinity Capture-MS Homo sapiens
104 Dusp14  
Two-hybrid Mus musculus
105 FOS 2353
Affinity Capture-MS Homo sapiens
106 RPA3 6119
Proximity Label-MS Homo sapiens
107 ZNF780A  
Affinity Capture-MS Homo sapiens
108 SEC16A 9919
Affinity Capture-MS Homo sapiens
109 HOXC4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
110 BAP1 8314
Affinity Capture-MS Homo sapiens
111 HSPA1A 3303
Affinity Capture-MS Homo sapiens
112 RPN1 6184
Affinity Capture-MS Homo sapiens
113 FOXQ1  
Affinity Capture-MS Homo sapiens
114 CCDC140  
Affinity Capture-MS Homo sapiens
115 MYH10 4628
Co-fractionation Homo sapiens
116 NEUROG3  
Affinity Capture-MS Homo sapiens
117 ZC3H3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
118 ZNF263  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
119 SOX2  
Affinity Capture-MS Homo sapiens
120 OST4  
Affinity Capture-MS Homo sapiens
121 H2AFX 3014
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
122 C6orf222  
Affinity Capture-MS Homo sapiens
123 SFRP4 6424
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
124 FGF11  
Affinity Capture-MS Homo sapiens
125 BCAS2 10286
Two-hybrid Homo sapiens
126 ATXN1L  
Two-hybrid Homo sapiens
127 APEX1 328
Affinity Capture-RNA Homo sapiens
128 LENG8  
Two-hybrid Homo sapiens
129 SQSTM1 8878
Proximity Label-MS Homo sapiens
130 UTP23  
Affinity Capture-MS Homo sapiens
131 UNC93B1 81622
Affinity Capture-MS Homo sapiens
132 EIF4A3 9775
Two-hybrid Homo sapiens
133 NUP35 129401
Proximity Label-MS Homo sapiens
134 NPAS1  
Affinity Capture-MS Homo sapiens
135 YTHDF3  
Two-hybrid Homo sapiens
136 BRK1 55845
Affinity Capture-MS Homo sapiens
137 PRR20B  
Two-hybrid Homo sapiens
138 ANAPC2 29882
Proximity Label-MS Homo sapiens
139 GSTM3 2947
Affinity Capture-MS Homo sapiens
140 C6orf141  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
141 RBM23  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
142 NEIL1  
Affinity Capture-MS Homo sapiens
143 MOV10 4343
Affinity Capture-RNA Homo sapiens
144 PRR20E  
Two-hybrid Homo sapiens
145 GLI2  
Proximity Label-MS Homo sapiens
146 C16orf72 29035
Affinity Capture-MS Homo sapiens
147 SKA3  
Affinity Capture-MS Homo sapiens
148 CT45A5  
Affinity Capture-MS Homo sapiens
149 EXOSC8  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which ANKHD1 is involved
No pathways found





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