Gene description for HSD3B2
Gene name	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
Gene symbol	HSD3B2
Other names/aliases	HSD3B HSDB SDR11E2
Species	Homo sapiens
Database cross references - HSD3B2
ExoCarta	ExoCarta_3284
Vesiclepedia	VP_3284
Entrez Gene	3284
HGNC	5218
MIM	613890
UniProt	P26439
HSD3B2 identified in sEVs derived from the following tissue/cell type
Hepatocytes	26054723

Gene ontology annotations for HSD3B2

Molecular Function     3-beta-hydroxy-delta5-steroid dehydrogenase (NAD+) activity GO:0003854 IDA     3-beta-hydroxy-delta5-steroid dehydrogenase (NAD+) activity GO:0003854 IMP     steroid delta-isomerase activity GO:0004769 IDA     steroid delta-isomerase activity GO:0004769 IMP     protein binding GO:0005515 IPI     oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0016616 IBA Biological Process     steroid biosynthetic process GO:0006694 IBA     steroid biosynthetic process GO:0006694 IDA     steroid biosynthetic process GO:0006694 IMP     androgen biosynthetic process GO:0006702 IMP     C21-steroid hormone metabolic process GO:0008207 IBA Subcellular Localization     nucleolus GO:0005730 IDA     cytoplasm GO:0005737 IBA     mitochondrial inner membrane GO:0005743 ISS     mitochondrial intermembrane space GO:0005758 ISS     endoplasmic reticulum GO:0005783 IDA     endoplasmic reticulum GO:0005783 IMP     endoplasmic reticulum GO:0005783 NAS     endoplasmic reticulum membrane GO:0005789 TAS     membrane GO:0016020 NAS     smooth endoplasmic reticulum membrane GO:0030868 ISS     mitochondrial membrane GO:0031966 NAS     intracellular membrane-bounded organelle GO:0043231 IBA     intercellular bridge GO:0045171 IDA