Gene description for SH3GLB1
Gene name
SH3-domain GRB2-like endophilin B1
Gene symbol
SH3GLB1
Other names/aliases
Bif-1 CGI-61 PPP1R70 dJ612B15.2
Species
Homo sapiens
Database cross references - SH3GLB1
ExoCarta
ExoCarta_51100
Entrez Gene
51100
HGNC
10833
MIM
609287
UniProt
Q9Y371
SH3GLB1 identified in exosomes derived from the following tissue/cell type
Ovarian cancer cells
23333927
Ovarian cancer cells
23333927
Gene ontology annotations for SH3GLB1
Experiment description of studies that identified SH3GLB1 in exosomes
1
Experiment ID
211
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|Alix
EV Cytosolic markers
✔
EpCAM|TFRC
EV Membrane markers
✔
cytochrome c|GOLGA2
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
IGROV1
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
2
Experiment ID
212
ISEV standards
✔
CEM
EV Biophysical techniques
✔
TSG101|Alix
EV Cytosolic markers
✔
EpCAM|TFRC
EV Membrane markers
✔
Cytochrome C|GOLGA2
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
OVCAR-3
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
Protein-protein interactions for SH3GLB1
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
SH3GLB2
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
Affinity Capture-Western
Homo sapiens
2
ARHGAP17
55114
Reconstituted Complex
Homo sapiens
3
HTT
3064
Reconstituted Complex
Homo sapiens
4
Map4k3
Reconstituted Complex
Rattus norvegicus
Affinity Capture-Western
Rattus norvegicus
Reconstituted Complex
Rattus norvegicus
Affinity Capture-Western
Rattus norvegicus
5
SH3KBP1
30011
Reconstituted Complex
Homo sapiens
6
DNM1
1759
Reconstituted Complex
Homo sapiens
7
BAX
581
Affinity Capture-MS
Homo sapiens
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
Affinity Capture-Western
Homo sapiens
8
AMPH
Reconstituted Complex
Homo sapiens
9
BIN1
274
Reconstituted Complex
Homo sapiens
View the network
image/svg+xml
Pathways in which SH3GLB1 is involved
No pathways found