Gene description for RRP36
Gene name ribosomal RNA processing 36 homolog (S. cerevisiae)
Gene symbol RRP36
Other names/aliases C6orf153
dJ20C7.4
Species Homo sapiens
 Database cross references - RRP36
ExoCarta ExoCarta_88745
Entrez Gene 88745
HGNC 21374
MIM 613475
UniProt Q96EU6  
 RRP36 identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for RRP36
Molecular Function
    poly(A) RNA binding GO:0044822 IDA
Biological Process
    rRNA processing GO:0006364 IDA
    ribosomal small subunit biogenesis GO:0042274 IDA
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GO:0000462 IBA
Subcellular Localization
    nucleolus GO:0005730 IDA
    90S preribosome GO:0030686 IBA
    nucleus GO:0005634 IDA
 Experiment description of studies that identified RRP36 in exosomes
1
Experiment ID 237
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for RRP36
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which RRP36 is involved
No pathways found





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