Gene description for MAP2K3
Gene name	mitogen-activated protein kinase kinase 3
Gene symbol	MAP2K3
Other names/aliases	MAPKK3 MEK3 MKK3 PRKMK3 SAPKK-2 SAPKK2
Species	Homo sapiens
Database cross references - MAP2K3
ExoCarta	ExoCarta_5606
Entrez Gene	5606
HGNC	6843
MIM	602315
UniProt	P46734
MAP2K3 identified in exosomes derived from the following tissue/cell type
Thymus	23844026

Gene ontology annotations for MAP2K3

Molecular Function     protein tyrosine kinase activity GO:0004713 IEA     MAP kinase kinase activity GO:0004708 IEA     protein serine/threonine kinase activity GO:0004674 IBA     protein kinase binding GO:0019901 IPI     ATP binding GO:0005524 IEA     protein binding GO:0005515 IPI Biological Process     signal transduction by protein phosphorylation GO:0023014 IBA     toll-like receptor 5 signaling pathway GO:0034146 TAS     regulation of apoptotic process GO:0042981 IBA     toll-like receptor TLR6:TLR2 signaling pathway GO:0038124 TAS     TRIF-dependent toll-like receptor signaling pathway GO:0035666 TAS     toll-like receptor 4 signaling pathway GO:0034142 TAS     toll-like receptor 9 signaling pathway GO:0034162 TAS     stress-activated MAPK cascade GO:0051403 TAS     MyD88-independent toll-like receptor signaling pathway GO:0002756 TAS     positive regulation of transcription, DNA-templated GO:0045893 IDA     regulation of cytokine biosynthetic process GO:0042035 IEA     stress-activated protein kinase signaling cascade GO:0031098 IBA     cardiac muscle contraction GO:0060048 IEA     regulation of mitotic cell cycle GO:0007346 IBA     toll-like receptor 3 signaling pathway GO:0034138 TAS     inflammatory response GO:0006954 IEA     toll-like receptor 10 signaling pathway GO:0034166 TAS     MyD88-dependent toll-like receptor signaling pathway GO:0002755 TAS     toll-like receptor TLR1:TLR2 signaling pathway GO:0038123 TAS     signal transduction GO:0007165 TAS     toll-like receptor 2 signaling pathway GO:0034134 TAS     peptidyl-tyrosine phosphorylation GO:0018108 IEA     activation of MAPK activity GO:0000187 TAS     toll-like receptor signaling pathway GO:0002224 TAS     positive regulation of protein kinase activity GO:0045860 IDA     innate immune response GO:0045087 TAS Subcellular Localization     membrane GO:0016020 IDA     cytosol GO:0005829 TAS     nucleoplasm GO:0005654 TAS     cytoplasm GO:0005737 IBA