Experiment description of studies that identified ADGRG2 in sEVs

1 Experiment ID 275 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81 Enriched markers ✔ AIF Negative markers ✔ NTA Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25844599     Organism Homo sapiens Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T." Journal name Oncotarget Publication year 2015 Sample Prostate cancer cells Sample name DU145 - Docetaxel sensitive Isolation/purification methods Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.12-1.19 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry/Flow cytometry/Western blotting

2 Experiment ID 66 MISEV standards ✔ IEM Biophysical techniques ✔ TSG101|Alix|CD63|CD81 Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 19199708     Organism Homo sapiens Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT). Authors "Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR" Journal name JPR Publication year 2009 Sample Saliva Sample name Saliva Isolation/purification methods Differential centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] Western blotting Immunoelectron Microscopy

Protein-protein interactions for ADGRG2

Protein Interactor ExoCarta ID Identification method PubMed Species 1 TUBGCP4 27229 Affinity Capture-MS Homo sapiens 2 GMIP   Affinity Capture-MS Homo sapiens 3 CERS6   Affinity Capture-MS Homo sapiens 4 ARFGEF1 10565 Affinity Capture-MS Homo sapiens 5 RIF1   Affinity Capture-MS Homo sapiens 6 CFAP69   Affinity Capture-MS Homo sapiens 7 GPR89A   Affinity Capture-MS Homo sapiens 8 SLC7A3   Affinity Capture-MS Homo sapiens 9 ATM 472 Affinity Capture-MS Homo sapiens 10 INTS1 26173 Affinity Capture-MS Homo sapiens 11 GPR50   Affinity Capture-MS Homo sapiens View the network

Pathways in which ADGRG2 is involved

No pathways found