Gene description for MAP2K7
Gene name	mitogen-activated protein kinase kinase 7
Gene symbol	MAP2K7
Other names/aliases	JNKK2 MAPKK7 MEK MEK 7 MKK7 PRKMK7 SAPKK-4 SAPKK4
Species	Homo sapiens
Database cross references - MAP2K7
ExoCarta	ExoCarta_5609
Entrez Gene	5609
HGNC	6847
MIM	603014
UniProt	O14733
MAP2K7 identified in exosomes derived from the following tissue/cell type
Thymus	23844026

Gene ontology annotations for MAP2K7

Molecular Function     protein binding GO:0005515 IPI     MAP kinase kinase activity GO:0004708 IDA     protein tyrosine kinase activity GO:0004713 IEA     mitogen-activated protein kinase kinase kinase binding GO:0031435 IEA     protein kinase binding GO:0019901 IPI     JUN kinase kinase activity GO:0008545 IBA     protein phosphatase binding GO:0019903 ISS     ATP binding GO:0005524 IEA     enzyme binding GO:0019899 IPI     protein serine/threonine kinase activity GO:0004674 IEA     magnesium ion binding GO:0000287 IDA     protein C-terminus binding GO:0008022 IEA Biological Process     toll-like receptor TLR1:TLR2 signaling pathway GO:0038123 TAS     toll-like receptor 9 signaling pathway GO:0034162 TAS     JNK cascade GO:0007254 TAS     response to UV GO:0009411 IDA     MyD88-dependent toll-like receptor signaling pathway GO:0002755 TAS     innate immune response GO:0045087 TAS     TRIF-dependent toll-like receptor signaling pathway GO:0035666 TAS     positive regulation of neuron apoptotic process GO:0043525 IEA     Fc-epsilon receptor signaling pathway GO:0038095 TAS     cellular response to sorbitol GO:0072709 IEA     toll-like receptor 10 signaling pathway GO:0034166 TAS     toll-like receptor 3 signaling pathway GO:0034138 TAS     apoptotic process GO:0006915 IEA     response to tumor necrosis factor GO:0034612 IDA     toll-like receptor signaling pathway GO:0002224 TAS     MyD88-independent toll-like receptor signaling pathway GO:0002756 TAS     stress-activated MAPK cascade GO:0051403 TAS     response to osmotic stress GO:0006970 IDA     toll-like receptor TLR6:TLR2 signaling pathway GO:0038124 TAS     peptidyl-tyrosine phosphorylation GO:0018108 IEA     toll-like receptor 2 signaling pathway GO:0034134 TAS     response to heat GO:0009408 IDA     toll-like receptor 5 signaling pathway GO:0034146 TAS     signal transduction GO:0007165 TAS     toll-like receptor 4 signaling pathway GO:0034142 TAS     activation of JUN kinase activity GO:0007257 ISS Subcellular Localization     nucleus GO:0005634 ISS     cytoplasm GO:0005737 ISS     intracellular GO:0005622 IBA     cytosol GO:0005829 TAS