Gene description for EIF1AD
Gene name eukaryotic translation initiation factor 1A domain containing
Gene symbol EIF1AD
Other names/aliases haponin
Species Homo sapiens
 Database cross references - EIF1AD
ExoCarta ExoCarta_84285
Vesiclepedia VP_84285
Entrez Gene 84285
HGNC 28147
UniProt Q8N9N8  
 EIF1AD identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for EIF1AD
Molecular Function
    RNA binding GO:0003723 IEA
    translation initiation factor activity GO:0003743 IEA
    protein binding GO:0005515 IPI
Biological Process
    translational initiation GO:0006413 IEA
Subcellular Localization
    nucleus GO:0005634 IBA
    nucleoplasm GO:0005654 IDA
    cytosol GO:0005829 IDA
    intracellular membrane-bounded organelle GO:0043231 IDA
 Experiment description of studies that identified EIF1AD in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for EIF1AD
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CAMKV 79012
Affinity Capture-MS Homo sapiens
2 RIOK1 83732
Affinity Capture-MS Homo sapiens
3 TRMT1L 81627
Affinity Capture-MS Homo sapiens
4 AES 166
Two-hybrid Homo sapiens
5 GAS8  
Two-hybrid Homo sapiens
6 MID1 4281
Affinity Capture-MS Homo sapiens
7 STX11 8676
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
8 HOXB9  
Affinity Capture-MS Homo sapiens
9 RBM48  
Two-hybrid Homo sapiens
10 CARKD 55739
Affinity Capture-MS Homo sapiens
11 TBC1D23 55773
Affinity Capture-MS Homo sapiens
12 MAP4K5 11183
Affinity Capture-MS Homo sapiens
13 POLR1E  
Affinity Capture-MS Homo sapiens
14 CTC1  
Affinity Capture-MS Homo sapiens
15 ZBTB14  
Two-hybrid Homo sapiens
16 SNX27 81609
Affinity Capture-MS Homo sapiens
17 SDCBP 6386
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
18 RPS11 6205
Affinity Capture-MS Homo sapiens
19 RBPJ 3516
Affinity Capture-MS Homo sapiens
20 CASK 8573
Affinity Capture-MS Homo sapiens
21 HEXIM1 10614
Affinity Capture-MS Homo sapiens
22 GATA6  
Affinity Capture-MS Homo sapiens
23 ZNF280A  
Two-hybrid Homo sapiens
24 WDR45B 56270
Affinity Capture-MS Homo sapiens
25 CEP55 55165
Two-hybrid Homo sapiens
26 PINX1  
Two-hybrid Homo sapiens
27 CLNS1A 1207
Affinity Capture-MS Homo sapiens
28 DPPA2  
Two-hybrid Homo sapiens
29 AMPD2 271
Affinity Capture-MS Homo sapiens
30 RNF138  
Affinity Capture-MS Homo sapiens
31 CHEK1  
Affinity Capture-MS Homo sapiens
32 BEND7 222389
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
33 TBC1D5 9779
Two-hybrid Homo sapiens
34 MEOX2  
Two-hybrid Homo sapiens
35 IP6K1 9807
Affinity Capture-MS Homo sapiens
36 CSNK1E 1454
Affinity Capture-MS Homo sapiens
37 GCSAML  
Two-hybrid Homo sapiens
38 CEP76  
Two-hybrid Homo sapiens
39 CD3EAP  
Affinity Capture-MS Homo sapiens
40 CSNK1G3 1456
Affinity Capture-MS Homo sapiens
41 DIP2B 57609
Affinity Capture-MS Homo sapiens
42 HBS1L 10767
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
43 ECT2 1894
Affinity Capture-MS Homo sapiens
44 LRRC47 57470
Affinity Capture-MS Homo sapiens
45 OBFC1 79991
Affinity Capture-MS Homo sapiens
46 NXF1 10482
Affinity Capture-RNA Homo sapiens
47 AP2M1 1173
Two-hybrid Homo sapiens
48 DUS3L 56931
Affinity Capture-MS Homo sapiens
49 MREG  
Two-hybrid Homo sapiens
50 ZNF558  
Two-hybrid Homo sapiens
51 ZNF521  
Two-hybrid Homo sapiens
52 RASSF10  
Two-hybrid Homo sapiens
53 CSNK2A2 1459
Affinity Capture-MS Homo sapiens
54 KDM8  
Affinity Capture-MS Homo sapiens
55 SCLY  
Affinity Capture-MS Homo sapiens
56 ENTHD2  
Two-hybrid Homo sapiens
57 RPS16 6217
Affinity Capture-MS Homo sapiens
58 PSMC3IP  
Affinity Capture-MS Homo sapiens
59 ARRB2 409
Affinity Capture-MS Homo sapiens
60 MPP6 51678
Affinity Capture-MS Homo sapiens
61 GRK6 2870
Affinity Capture-MS Homo sapiens
62 MCAT 27349
Affinity Capture-MS Homo sapiens
63 SDCBP2 27111
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
64 PDCD2L 84306
Affinity Capture-MS Homo sapiens
65 ZBTB8A  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
66 DLG3 1741
Affinity Capture-MS Homo sapiens
67 MTERF1  
Affinity Capture-MS Homo sapiens
68 TRMT61B  
Affinity Capture-MS Homo sapiens
69 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
70 RBAK  
Two-hybrid Homo sapiens
71 CCDC106  
Two-hybrid Homo sapiens
72 PBX4  
Two-hybrid Homo sapiens
73 KLHL42  
Affinity Capture-MS Homo sapiens
74 GNB1L 54584
Affinity Capture-MS Homo sapiens
75 MOV10 4343
Affinity Capture-RNA Homo sapiens
76 HNRNPLL 92906
Affinity Capture-MS Homo sapiens
77 UTP6  
Affinity Capture-MS Homo sapiens
78 MND1  
Affinity Capture-MS Homo sapiens
79 MGME1  
Affinity Capture-MS Homo sapiens
80 STAT1 6772
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
81 GLYR1 84656
Two-hybrid Homo sapiens
82 GTF2H4 2968
Two-hybrid Homo sapiens
83 KRAS 3845
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
84 GNB2L1 10399
Affinity Capture-MS Homo sapiens
85 ISL2  
Affinity Capture-MS Homo sapiens
86 POLD2 5425
Affinity Capture-MS Homo sapiens
87 TNNI1 7135
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which EIF1AD is involved
No pathways found





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