Gene description for TTC26
Gene name tetratricopeptide repeat domain 26
Gene symbol TTC26
Other names/aliases DYF13
dyf-13
Species Homo sapiens
 Database cross references - TTC26
ExoCarta ExoCarta_79989
Vesiclepedia VP_79989
Entrez Gene 79989
HGNC 21882
UniProt A0AVF1  
 TTC26 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for TTC26
Molecular Function
    intraciliary transport particle B binding GO:0120170 IBA
Biological Process
    smoothened signaling pathway GO:0007224 ISS
    protein transport GO:0015031 IEA
    axoneme assembly GO:0035082 ISS
    intraciliary anterograde transport GO:0035720 IBA
    intraciliary anterograde transport GO:0035720 NAS
    intraciliary transport involved in cilium assembly GO:0035735 IBA
    intraciliary transport GO:0042073 ISS
    cilium assembly GO:0060271 IMP
    cilium assembly GO:0060271 ISS
    cilium assembly GO:0060271 NAS
    protein localization to cilium GO:0061512 ISS
    manchette assembly GO:1905198 IEA
Subcellular Localization
    centrosome GO:0005813 IEA
    cilium GO:0005929 IMP
    cilium GO:0005929 ISS
    cilium GO:0005929 NAS
    cilium GO:0005929 TAS
    intraciliary transport particle B GO:0030992 IBA
    intraciliary transport particle B GO:0030992 IPI
    intraciliary transport particle B GO:0030992 ISS
    ciliary basal body GO:0036064 IBA
    neuron projection GO:0043005 IEA
    ciliary tip GO:0097542 TAS
    ciliary base GO:0097546 IBA
 Experiment description of studies that identified TTC26 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for TTC26
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 DNAJC7 7266
Proximity Label-MS Homo sapiens
2 IFT80 57560
Affinity Capture-MS Homo sapiens
3 HERC1 8925
Affinity Capture-MS Homo sapiens
4 IFT57 55081
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 TTC30A 92104
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 UFD1L 7353
Affinity Capture-MS Homo sapiens
7 HOOK1  
Proximity Label-MS Homo sapiens
8 NPLOC4 55666
Affinity Capture-MS Homo sapiens
9 RNF219  
Affinity Capture-MS Homo sapiens
10 FAM167A  
Affinity Capture-MS Homo sapiens
11 IFT20 90410
Affinity Capture-MS Homo sapiens
12 METTL10  
Affinity Capture-MS Homo sapiens
13 HSPA8 3312
Affinity Capture-MS Homo sapiens
14 XPO1 7514
Affinity Capture-MS Homo sapiens
15 BAG2 9532
Affinity Capture-MS Homo sapiens
16 UBXN10  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
17 HSPB11 51668
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
18 HK3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 FAM43A  
Affinity Capture-MS Homo sapiens
20 MLF1  
Affinity Capture-MS Homo sapiens
21 IFT27 11020
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
22 MARCH7  
Affinity Capture-MS Homo sapiens
23 GLI1  
Affinity Capture-MS Homo sapiens
24 ZNF579  
Affinity Capture-MS Homo sapiens
25 B4GALT2  
Affinity Capture-MS Homo sapiens
26 FKBP5 2289
Affinity Capture-MS Homo sapiens
27 TTC30B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
28 TUBA1A 7846
Affinity Capture-MS Homo sapiens
29 PANK4 55229
Affinity Capture-MS Homo sapiens
30 DNAJB8  
Proximity Label-MS Homo sapiens
31 PPP4R1L  
Affinity Capture-MS Homo sapiens
32 ABTB2 25841
Affinity Capture-MS Homo sapiens
33 PTPN21 11099
Affinity Capture-MS Homo sapiens
34 CDC16 8881
Affinity Capture-MS Homo sapiens
35 RCCD1  
Affinity Capture-MS Homo sapiens
36 IFT46 56912
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
37 TRMU  
Affinity Capture-MS Homo sapiens
38 NIN 51199
Proximity Label-MS Homo sapiens
39 AMZ1  
Affinity Capture-MS Homo sapiens
40 IFT52 51098
Affinity Capture-MS Homo sapiens
41 IFT88 8100
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
42 IFT74 80173
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
43 KLHL34  
Affinity Capture-MS Homo sapiens
44 BICD1 636
Proximity Label-MS Homo sapiens
45 KRT2 3849
Affinity Capture-MS Homo sapiens
46 ARL13B 200894
Affinity Capture-MS Homo sapiens
47 IFT81 28981
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
48 TUBB8 347688
Affinity Capture-MS Homo sapiens
49 IFT172 26160
Affinity Capture-MS Homo sapiens
50 HUWE1 10075
Affinity Capture-MS Homo sapiens
51 IFT22 64792
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
52 ATG7 10533
Affinity Capture-MS Homo sapiens
53 VCP 7415
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



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