Gene description for SPPL2B
Gene name signal peptide peptidase like 2B
Gene symbol SPPL2B
Other names/aliases IMP-4
IMP4
PSH4
PSL1
Species Homo sapiens
 Database cross references - SPPL2B
ExoCarta ExoCarta_56928
Vesiclepedia VP_56928
Entrez Gene 56928
HGNC 30627
MIM 608239
UniProt Q8TCT7  
 SPPL2B identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Mesenchymal stem cells 36408942    
 Gene ontology annotations for SPPL2B
Molecular Function
    protein binding GO:0005515 IPI
    aspartic endopeptidase activity, intramembrane cleaving GO:0042500 IDA
    aspartic endopeptidase activity, intramembrane cleaving GO:0042500 IMP
    aspartic endopeptidase activity, intramembrane cleaving GO:0042500 IMP
    aspartic endopeptidase activity, intramembrane cleaving GO:0042500 TAS
    protein homodimerization activity GO:0042803 IDA
Biological Process
    membrane protein ectodomain proteolysis GO:0006509 IDA
    regulation of tumor necrosis factor-mediated signaling pathway GO:0010803 TAS
    membrane protein intracellular domain proteolysis GO:0031293 IDA
    membrane protein intracellular domain proteolysis GO:0031293 IMP
    membrane protein proteolysis GO:0033619 IBA
    membrane protein proteolysis GO:0033619 IDA
    regulation of immune response GO:0050776 IMP
Subcellular Localization
    Golgi membrane GO:0000139 IEA
    nucleoplasm GO:0005654 IDA
    lysosomal membrane GO:0005765 IBA
    lysosomal membrane GO:0005765 IDA
    centrosome GO:0005813 IDA
    plasma membrane GO:0005886 IDA
    plasma membrane GO:0005886 TAS
    endosome membrane GO:0010008 IDA
    actin cytoskeleton GO:0015629 IDA
    membrane GO:0016020 IDA
    Golgi-associated vesicle membrane GO:0030660 IBA
    Golgi-associated vesicle membrane GO:0030660 IDA
    lumenal side of endoplasmic reticulum membrane GO:0098553 IBA
    lumenal side of endoplasmic reticulum membrane GO:0098553 IDA
    cytoplasmic side of endoplasmic reticulum membrane GO:0098554 IBA
    cytoplasmic side of endoplasmic reticulum membrane GO:0098554 IDA
 Experiment description of studies that identified SPPL2B in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for SPPL2B
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 PAQR7  
Affinity Capture-MS Homo sapiens
2 KDELR3 11015
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 PSME2 5721
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 TMCO1 54499
Affinity Capture-MS Homo sapiens
5 TOR1A 1861
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 TMBIM6 7009
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 CHRNA4  
Affinity Capture-MS Homo sapiens
8 TMEM161A  
Affinity Capture-MS Homo sapiens
9 SPPL3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 METTL7A 25840
Affinity Capture-MS Homo sapiens
11 TTYH3 80727
Affinity Capture-MS Homo sapiens
12 GALNT1 2589
Affinity Capture-MS Homo sapiens
13 SLC39A4 55630
Affinity Capture-MS Homo sapiens
14 ADGRG1 9289
Affinity Capture-MS Homo sapiens
15 HACD3 51495
Affinity Capture-MS Homo sapiens
16 TMED4 222068
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 KIAA2013 90231
Affinity Capture-MS Homo sapiens
18 CD300E  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 PGRMC2 10424
Affinity Capture-MS Homo sapiens
20 VMP1 81671
Affinity Capture-MS Homo sapiens
21 ATP12A 479
Affinity Capture-MS Homo sapiens
22 SYNE4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
23 SURF4 6836
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
24 MFSD5  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
25 SPNS1 83985
Affinity Capture-MS Homo sapiens
26 TMEM186  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
27 ROCK2 9475
Affinity Capture-MS Homo sapiens
28 MFSD8 256471
Affinity Capture-MS Homo sapiens
29 GPR114  
Affinity Capture-MS Homo sapiens
30 LRRC52  
Affinity Capture-MS Homo sapiens
31 SPINK4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
32 SLC22A9  
Affinity Capture-MS Homo sapiens
33 FAM20B 9917
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
34 TMEM55B 90809
Affinity Capture-MS Homo sapiens
35 CMTM4  
Affinity Capture-MS Homo sapiens
36 CADM1 23705
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
37 UQCRQ 27089
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
38 NR2F2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
39 PTDSS2 81490
Affinity Capture-MS Homo sapiens
40 PIGN 23556
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
41 ALG10  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
42 LMAN2L 81562
Affinity Capture-MS Homo sapiens
43 TNFRSF10B 8795
Affinity Capture-MS Homo sapiens
44 TMEM181 57583
Affinity Capture-MS Homo sapiens
45 GLG1 2734
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
46 NDUFB8 4714
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
47 TMEM41B 440026
Affinity Capture-MS Homo sapiens
48 SLC35G2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
49 TMEM8A 58986
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
50 MTCH1 23787
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
51 TMED2 10959
Affinity Capture-MS Homo sapiens
52 YIPF3 25844
Affinity Capture-MS Homo sapiens
53 KLRC1  
Affinity Capture-MS Homo sapiens
54 PSEN1 5663
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
55 RER1 11079
Affinity Capture-MS Homo sapiens
56 MAOB  
Affinity Capture-MS Homo sapiens
57 ATP2A3 489
Affinity Capture-MS Homo sapiens
58 NRN1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
59 MRS2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
60 STX18 53407
Affinity Capture-MS Homo sapiens
61 SLC30A5 64924
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
62 SIGMAR1 10280
Affinity Capture-MS Homo sapiens
63 PIGG  
Affinity Capture-MS Homo sapiens
64 LMAN2 10960
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
65 MAVS 57506
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
66 GPX8 493869
Affinity Capture-MS Homo sapiens
67 MLLT1 4298
Affinity Capture-MS Homo sapiens
68 COX1 4512
Affinity Capture-MS Homo sapiens
69 SLC38A5 92745
Affinity Capture-MS Homo sapiens
70 DHCR24 1718
Affinity Capture-MS Homo sapiens
71 PTH1R  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
72 DGAT1 8694
Affinity Capture-MS Homo sapiens
73 ATP1A3 478
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
74 MICA 100507436
Affinity Capture-MS Homo sapiens
75 NDUFB1 4707
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
76 VKORC1L1 154807
Affinity Capture-MS Homo sapiens
77 RCE1  
Affinity Capture-MS Homo sapiens
78 CADM4 199731
Affinity Capture-MS Homo sapiens
79 EXTL3 2137
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
80 CD70 970
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
81 HTR3C  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
82 MOXD1 26002
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
83 MTCH2 23788
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
84 KLRC4  
Affinity Capture-MS Homo sapiens
85 HS2ST1 9653
Affinity Capture-MS Homo sapiens
86 ATP1B4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
87 POTEI 653269
Affinity Capture-MS Homo sapiens
88 NPC1 4864
Affinity Capture-MS Homo sapiens
89 FUT8 2530
Affinity Capture-MS Homo sapiens
90 TMEM126A 84233
Affinity Capture-MS Homo sapiens
91 MCOLN1 57192
Affinity Capture-MS Homo sapiens
92 TMEM165 55858
Affinity Capture-MS Homo sapiens
93 NBR1 4077
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
94 TSPAN3 10099
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
95 TLCD1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
96 COX14  
Affinity Capture-MS Homo sapiens
97 ACP2 53
Affinity Capture-MS Homo sapiens
98 TMEM43 79188
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
99 CHRNB2  
Affinity Capture-MS Homo sapiens
100 CHPT1  
Affinity Capture-MS Homo sapiens
101 PIGM  
Affinity Capture-MS Homo sapiens
102 HAS3  
Affinity Capture-MS Homo sapiens
103 ATP9A 10079
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
104 PIGT 51604
Affinity Capture-MS Homo sapiens
105 GNPTAB 79158
Affinity Capture-MS Homo sapiens
106 LAMP1 3916
Affinity Capture-MS Homo sapiens
107 SLC43A3 29015
Affinity Capture-MS Homo sapiens
108 CYC1 1537
Affinity Capture-MS Homo sapiens
109 PIGS 94005
Affinity Capture-MS Homo sapiens
110 UPK1A 11045
Affinity Capture-MS Homo sapiens
111 UQCRH 7388
Affinity Capture-MS Homo sapiens
112 PDGFRA 5156
Affinity Capture-MS Homo sapiens
113 USP28 57646
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
114 TMED1 11018
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
115 CHRND  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
116 CLN6  
Affinity Capture-MS Homo sapiens
117 C15orf32  
Affinity Capture-MS Homo sapiens
118 ERGIC3 51614
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
119 P2RX4 5025
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
120 HTR3A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
121 CDS2 8760
Affinity Capture-MS Homo sapiens
122 TMED9 54732
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
123 AGPAT6 137964
Affinity Capture-MS Homo sapiens
124 TTYH1  
Affinity Capture-MS Homo sapiens
125 CANX 821
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
126 TMED3 23423
Affinity Capture-MS Homo sapiens
127 ATF6  
Affinity Capture-MS Homo sapiens
128 YIPF6 286451
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
129 GLMN 11146
Affinity Capture-MS Homo sapiens
130 B3GALT6 126792
Affinity Capture-MS Homo sapiens
131 CCNYL1 151195
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
132 TVP23C  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
133 CAV2 858
Affinity Capture-MS Homo sapiens
134 PON2 5445
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
135 SLC35F2 54733
Affinity Capture-MS Homo sapiens
136 SLC30A6 55676
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
137 CRELD1 78987
Affinity Capture-MS Homo sapiens
138 CASC4 113201
Affinity Capture-MS Homo sapiens
139 ENDOD1 23052
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
140 FITM2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
141 RMND1 55005
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
142 NIPAL1  
Affinity Capture-MS Homo sapiens
143 FXYD6  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
144 TMEM246 84302
Affinity Capture-MS Homo sapiens
145 YIPF5 81555
Affinity Capture-MS Homo sapiens
146 GHITM 27069
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
147 SLC39A1 27173
Affinity Capture-MS Homo sapiens
148 LPAR1 1902
Affinity Capture-MS Homo sapiens
149 ABHD12 26090
Affinity Capture-MS Homo sapiens
150 SERINC1 57515
Affinity Capture-MS Homo sapiens
151 TM9SF3 56889
Affinity Capture-MS Homo sapiens
152 SLC35B2 347734
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
153 GPAA1 8733
Affinity Capture-MS Homo sapiens
154 CHRNB4  
Affinity Capture-MS Homo sapiens
155 RFT1 91869
Affinity Capture-MS Homo sapiens
156 GPRC5C 55890
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
157 EMC2 9694
Affinity Capture-MS Homo sapiens
158 IGSF3 3321
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
159 PSCA 8000
Affinity Capture-MS Homo sapiens
160 YIPF4 84272
Affinity Capture-MS Homo sapiens
161 SLC30A7 148867
Affinity Capture-MS Homo sapiens
162 ATP1B1 481
Affinity Capture-MS Homo sapiens
163 NDUFAF4 29078
Affinity Capture-MS Homo sapiens
164 CERS6  
Affinity Capture-MS Homo sapiens
165 ENTPD2 954
Affinity Capture-MS Homo sapiens
166 MPPE1 65258
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
167 SLC39A10 57181
Affinity Capture-MS Homo sapiens
168 ATP13A3 79572
Affinity Capture-MS Homo sapiens
169 CLGN 1047
Affinity Capture-MS Homo sapiens
170 NTSR1  
Affinity Capture-MS Homo sapiens
171 ENTPD7  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
172 QSOX2 169714
Affinity Capture-MS Homo sapiens
173 NDUFC2 4718
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
174 PEX3 8504
Affinity Capture-MS Homo sapiens
175 OSBPL8 114882
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
176 FAM187B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
177 SORL1 6653
Affinity Capture-MS Homo sapiens
178 EDDM3B  
Affinity Capture-MS Homo sapiens
179 NDUFS2 4720
Affinity Capture-MS Homo sapiens
180 TMEM231 79583
Affinity Capture-MS Homo sapiens
181 KTN1 3895
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
182 ATP1A2 477
Affinity Capture-MS Homo sapiens
183 MBOAT7 79143
Affinity Capture-MS Homo sapiens
184 CRLF2 64109
Affinity Capture-MS Homo sapiens
185 IFITM1 8519
Affinity Capture-MS Homo sapiens
186 SLC19A2 10560
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
187 PIGW  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
188 GPR89A  
Affinity Capture-MS Homo sapiens
189 KDELR1 10945
Affinity Capture-MS Homo sapiens
190 ABCB8 11194
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
191 AGPAT9  
Affinity Capture-MS Homo sapiens
192 SIDT2 51092
Affinity Capture-MS Homo sapiens
193 TXNDC15  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
194 PIGO  
Affinity Capture-MS Homo sapiens
195 GPR180  
Affinity Capture-MS Homo sapiens
196 TMEM63B 55362
Affinity Capture-MS Homo sapiens
197 EMC7 56851
Affinity Capture-MS Homo sapiens
198 CLEC2D  
Affinity Capture-MS Homo sapiens
199 PTCH1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
200 CLPTM1 1209
Affinity Capture-MS Homo sapiens
201 EXTL2 2135
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
202 UNC93B1 81622
Affinity Capture-MS Homo sapiens
203 PIGU 128869
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
204 SLC39A14 23516
Affinity Capture-MS Homo sapiens
205 DDX58 23586
Affinity Capture-RNA Homo sapiens
206 ND4 4538
Affinity Capture-MS Homo sapiens
207 CEP44  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
208 SCN4A  
Affinity Capture-MS Homo sapiens
209 HACD2 201562
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
210 ERGIC2 51290
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
211 UXS1 80146
Affinity Capture-MS Homo sapiens
212 SLC11A2 4891
Affinity Capture-MS Homo sapiens
213 PLD6  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
214 GOLGA5 9950
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
215 SLC52A2 79581
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
216 ATP1A1 476
Affinity Capture-MS Homo sapiens
217 CDR2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
218 CLPTM1L 81037
Affinity Capture-MS Homo sapiens
219 CHRNE  
Affinity Capture-MS Homo sapiens
220 CCR6  
Affinity Capture-MS Homo sapiens
221 SLC8A3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
222 SLC7A1 6541
Affinity Capture-MS Homo sapiens
223 CHRNB1  
Affinity Capture-MS Homo sapiens
224 ADIPOR1 51094
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
225 BRI3BP 140707
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
226 PVRL3 25945
Affinity Capture-MS Homo sapiens
227 MGST3 4259
Affinity Capture-MS Homo sapiens
228 GNB2 2783
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which SPPL2B is involved
PathwayEvidenceSource
Death Receptor Signaling TAS Reactome
Regulation of TNFR1 signaling TAS Reactome
Signal Transduction TAS Reactome
TNF signaling TAS Reactome





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