Gene description for FGFRL1
Gene name fibroblast growth factor receptor-like 1
Gene symbol FGFRL1
Other names/aliases FGFR5
FHFR
Species Homo sapiens
 Database cross references - FGFRL1
ExoCarta ExoCarta_53834
Entrez Gene 53834
HGNC 3693
MIM 605830
UniProt Q8N441  
 FGFRL1 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for FGFRL1
Molecular Function
    fibroblast growth factor-activated receptor activity GO:0005007 IDA
    fibroblast growth factor binding GO:0017134 IEA
    heparin binding GO:0008201 IMP
Biological Process
    cell-cell adhesion via plasma-membrane adhesion molecules GO:0098742 IMP
    diaphragm development GO:0060539 IEA
    ventricular septum morphogenesis GO:0060412 IEA
    protein homooligomerization GO:0051260 IMP
    fibroblast growth factor receptor signaling pathway GO:0008543 IEA
    substrate adhesion-dependent cell spreading GO:0034446 IDA
    protein heterooligomerization GO:0051291 IGI
    skeletal system development GO:0001501 IEA
    negative regulation of cell proliferation GO:0008285 IEA
    heart valve morphogenesis GO:0003179 IEA
Subcellular Localization
    integral component of membrane GO:0016021 IEA
    transport vesicle GO:0030133 IDA
    Golgi apparatus GO:0005794 IDA
    plasma membrane GO:0005886 IDA
    cell-cell contact zone GO:0044291 IDA
 Experiment description of studies that identified FGFRL1 in exosomes
1
Experiment ID 126
ISEV standards
✘ EV Biophysical techniques
✔
GAPDH
EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Antibody array
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for FGFRL1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which FGFRL1 is involved
No pathways found





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