Gene description for KRT78
Gene name keratin 78, type II
Gene symbol KRT78
Other names/aliases CK-78
K5B
K78
Kb40
Species Homo sapiens
 Database cross references - KRT78
ExoCarta ExoCarta_196374
Entrez Gene 196374
HGNC 28926
MIM 611159
UniProt Q8N1N4  
 KRT78 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
Saliva 19199708    
 Gene ontology annotations for KRT78
Molecular Function
    structural molecule activity GO:0005198 IEA
Subcellular Localization
    keratin filament GO:0045095 IEA
    extracellular space GO:0005615 IDA
    extracellular exosome GO:0070062 IDA
 Experiment description of studies that identified KRT78 in exosomes
1
Experiment ID 126
ISEV standards
EV Biophysical techniques
GAPDH
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
2
Experiment ID 66
ISEV standards
IEM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
CD63|CD81
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19199708    
Organism Homo sapiens
Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Authors Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR
Journal name JPR
Publication year 2009
Sample Saliva
Sample name Saliva
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for KRT78
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SIRT2 22933
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which KRT78 is involved
No pathways found





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