Gene description for MMP9
Gene name	matrix metallopeptidase 9
Gene symbol	MMP9
Other names/aliases	CLG4B GELB MANDP2 MMP-9
Species	Homo sapiens
Database cross references - MMP9
ExoCarta	ExoCarta_4318
Entrez Gene	4318
HGNC	7176
MIM	120361
UniProt	P14780
MMP9 identified in exosomes derived from the following tissue/cell type
Keratinocytes	19530224
Keratinocytes	19530224

Gene ontology annotations for MMP9

Molecular Function     protein binding GO:0005515 IPI     endopeptidase activity GO:0004175 IDA     metallopeptidase activity GO:0008237 IDA     zinc ion binding GO:0008270 TAS     identical protein binding GO:0042802 IPI     metalloendopeptidase activity GO:0004222 IDA     collagen binding GO:0005518 TAS Biological Process     ossification GO:0001503 IEA     negative regulation of intrinsic apoptotic signaling pathway GO:2001243 IMP     positive regulation of keratinocyte migration GO:0051549 IMP     negative regulation of apoptotic process GO:0043066 IMP     endodermal cell differentiation GO:0035987 IEP     positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 IMP     collagen catabolic process GO:0030574 TAS     embryo implantation GO:0007566 IEA     leukocyte migration GO:0050900 IEA     positive regulation of protein phosphorylation GO:0001934 IMP     proteolysis GO:0006508 IDA     positive regulation of release of cytochrome c from mitochondria GO:0090200 IMP     negative regulation of cation channel activity GO:2001258 IDA     negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway GO:2001268 IMP     extracellular matrix disassembly GO:0022617 TAS     skeletal system development GO:0001501 IEA     extracellular matrix organization GO:0030198 TAS     ephrin receptor signaling pathway GO:0048013 TAS     axon guidance GO:0007411 TAS     macrophage differentiation GO:0030225 TAS     positive regulation of DNA binding GO:0043388 IDA     positive regulation of receptor binding GO:1900122 IDA Subcellular Localization     proteinaceous extracellular matrix GO:0005578 IEA     extracellular region GO:0005576 TAS     extracellular space GO:0005615 IDA     extracellular exosome GO:0070062 IDA