Gene description for ANAPC7
Gene name anaphase promoting complex subunit 7
Gene symbol ANAPC7
Other names/aliases APC7
Species Homo sapiens
 Database cross references - ANAPC7
ExoCarta ExoCarta_51434
Entrez Gene 51434
HGNC 17380
MIM 606949
UniProt Q9UJX3  
 ANAPC7 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for ANAPC7
Molecular Function
    protein phosphatase binding GO:0019903 IPI
Biological Process
    cell division GO:0051301 IEA
    mitotic spindle assembly checkpoint GO:0007094 TAS
    protein K11-linked ubiquitination GO:0070979 IDA
    mitotic nuclear division GO:0007067 IEA
    regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle GO:0051439 TAS
    negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle GO:0051436 TAS
    mitotic cell cycle GO:0000278 TAS
    anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 TAS
    positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition GO:0051437 TAS
Subcellular Localization
    anaphase-promoting complex GO:0005680 IDA
    nucleoplasm GO:0005654 TAS
    nucleus GO:0005634 IDA
    cytosol GO:0005829 TAS
 Experiment description of studies that identified ANAPC7 in exosomes
Experiment ID 217
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ANAPC7
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ANAPC4  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
2 CDC20  
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
3 APC2  
Affinity Capture-Western Homo sapiens
4 ANAPC5 51433
Reconstituted Complex Homo sapiens
5 FZR1  
Reconstituted Complex Homo sapiens
6 CDH1 999
Reconstituted Complex Homo sapiens
7 ANAPC1 64682
Reconstituted Complex Homo sapiens
Co-purification Homo sapiens
8 CDC27 996
Affinity Capture-Western Homo sapiens
View the network image/svg+xml

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