Gene description for SERPINB13
Gene name serpin peptidase inhibitor, clade B (ovalbumin), member 13
Gene symbol SERPINB13
Other names/aliases HSHUR7SEQ
Species Homo sapiens
 Database cross references - SERPINB13
ExoCarta ExoCarta_5275
Entrez Gene 5275
HGNC 8944
MIM 604445
UniProt Q9UIV8  
 SERPINB13 identified in exosomes derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for SERPINB13
Molecular Function
    cysteine-type endopeptidase inhibitor activity GO:0004869 IMP
    serine-type endopeptidase inhibitor activity GO:0004867 NAS
    protease binding GO:0002020 IPI
Biological Process
    regulation of proteolysis GO:0030162 NAS
    response to UV GO:0009411 TAS
    negative regulation of keratinocyte apoptotic process GO:1902173 IMP
    negative regulation of endopeptidase activity GO:0010951 IDA
Subcellular Localization
    cytoplasm GO:0005737 IDA
    extracellular space GO:0005615 IBA
    nucleolus GO:0005730 IDA
    extracellular exosome GO:0070062 IDA
    nucleoplasm GO:0005654 IDA
 Experiment description of studies that identified SERPINB13 in exosomes
Experiment ID 63
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for SERPINB13
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CTSL 1514
Invitro Homo sapiens
2 CTSK  
Invitro Homo sapiens
3 CTSG 1511
Invitro Homo sapiens
View the network image/svg+xml
 Pathways in which SERPINB13 is involved
No pathways found

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