Gene description for ACVR1B
Gene name	activin A receptor, type IB
Gene symbol	ACVR1B
Other names/aliases	ACTRIB ACVRLK4 ALK4 SKR2
Species	Homo sapiens
Database cross references - ACVR1B
ExoCarta	ExoCarta_91
Vesiclepedia	VP_91
Entrez Gene	91
HGNC	172
MIM	601300
UniProt	P36896
ACVR1B identified in exosomes derived from the following tissue/cell type
Ovarian cancer cells	23333927
Ovarian cancer cells	23333927

Gene ontology annotations for ACVR1B

Molecular Function     protein serine/threonine kinase activity GO:0004674 EXP     protein serine/threonine kinase activity GO:0004674 IDA     protein serine/threonine kinase activity GO:0004674 TAS     transmembrane receptor protein serine/threonine kinase activity GO:0004675 NAS     transforming growth factor beta receptor activity, type I GO:0005025 IEA     transforming growth factor beta receptor activity, type II GO:0005026 IEA     protein binding GO:0005515 IPI     ATP binding GO:0005524 IDA     activin receptor activity, type I GO:0016361 IBA     activin receptor activity, type I GO:0016361 IDA     activin receptor activity, type I GO:0016361 TAS     activin receptor activity, type II GO:0016362 IEA     activin receptor activity GO:0017002 IDA     activin receptor activity GO:0017002 IDA     growth factor binding GO:0019838 IPI     ubiquitin protein ligase binding GO:0031625 IPI     inhibin binding GO:0034711 IPI     SMAD binding GO:0046332 IDA     metal ion binding GO:0046872 IEA     activin binding GO:0048185 IDA     transforming growth factor beta receptor activity, type III GO:0070123 IEA     I-SMAD binding GO:0070411 IPI     BMP receptor activity GO:0098821 IEA Biological Process     G1/S transition of mitotic cell cycle GO:0000082 IDA     in utero embryonic development GO:0001701 IEA     hair follicle development GO:0001942 IEA     regulation of DNA-templated transcription GO:0006355 IDA     signal transduction GO:0007165 IDA     cell surface receptor protein serine/threonine kinase signaling pathway GO:0007178 TAS     nervous system development GO:0007399 IBA     positive regulation of gene expression GO:0010628 IEA     negative regulation of gene expression GO:0010629 IEA     peptidyl-threonine phosphorylation GO:0018107 IDA     negative regulation of ossification GO:0030279 IDA     negative regulation of cell growth GO:0030308 IDA     BMP signaling pathway GO:0030509 IEA     activin receptor signaling pathway GO:0032924 IBA     activin receptor signaling pathway GO:0032924 IDA     activin receptor signaling pathway GO:0032924 IMP     positive regulation of activin receptor signaling pathway GO:0032927 IDA     nodal signaling pathway GO:0038092 IGI     positive regulation of erythrocyte differentiation GO:0045648 IDA     protein autophosphorylation GO:0046777 IDA     cellular response to growth factor stimulus GO:0071363 IBA     extrinsic apoptotic signaling pathway GO:0097191 IMP     positive regulation of trophoblast cell migration GO:1901165 IDA Subcellular Localization     cytosol GO:0005829 IDA     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 IDA     plasma membrane GO:0005886 TAS     cell surface GO:0009986 IDA     receptor complex GO:0043235 IDA     activin receptor complex GO:0048179 IBA     activin receptor complex GO:0048179 IDA