Gene description for STAT6
Gene name	signal transducer and activator of transcription 6, interleukin-4 induced
Gene symbol	STAT6
Other names/aliases	D12S1644 IL-4-STAT STAT6B STAT6C
Species	Homo sapiens
Database cross references - STAT6
ExoCarta	ExoCarta_6778
Entrez Gene	6778
HGNC	11368
MIM	601512
UniProt	P42226
STAT6 identified in exosomes derived from the following tissue/cell type
Hepatocytes	26054723
Melanoma cells	25950383
Thymus	23844026

Gene ontology annotations for STAT6

Molecular Function     signal transducer activity GO:0004871 IEA     sequence-specific DNA binding transcription factor activity GO:0003700 IEA     RNA polymerase II core promoter sequence-specific DNA binding GO:0000979 IEA     protein phosphatase binding GO:0019903 IPI     identical protein binding GO:0042802 IPI     protein binding GO:0005515 IPI Biological Process     mammary gland morphogenesis GO:0060443 IEA     negative regulation of transcription from RNA polymerase II promoter GO:0000122 IEA     regulation of transcription from RNA polymerase II promoter GO:0006357 TAS     interleukin-4-mediated signaling pathway GO:0035771 IMP     transcription, DNA-templated GO:0006351 IEA     positive regulation of transcription from RNA polymerase II promoter GO:0045944 IEA     positive regulation of isotype switching to IgE isotypes GO:0048295 IEA     cellular response to reactive nitrogen species GO:1902170 IEA     positive regulation of type I interferon production GO:0032481 TAS     negative regulation of type 2 immune response GO:0002829 IEA     mammary gland epithelial cell proliferation GO:0033598 IEA     signal transduction GO:0007165 TAS     innate immune response GO:0045087 TAS     regulation of cell proliferation GO:0042127 IEA     cellular response to hydrogen peroxide GO:0070301 IEA     T-helper 1 cell lineage commitment GO:0002296 IEA Subcellular Localization     nucleoplasm GO:0005654 TAS     cytoplasm GO:0005737 IDA     nuclear chromatin GO:0000790 IEA     cytosol GO:0005829 TAS     membrane raft GO:0045121 IEA