Gene description for KIAA1598
Gene name KIAA1598
Gene symbol KIAA1598
Other names/aliases -
Species Homo sapiens
 Database cross references - KIAA1598
ExoCarta ExoCarta_57698
Entrez Gene 57698
HGNC 29319
MIM 611171
UniProt A0MZ66  
 KIAA1598 identified in exosomes derived from the following tissue/cell type
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
 Gene ontology annotations for KIAA1598
Molecular Function
    protein binding GO:0005515 IPI
    kinase binding GO:0019900 IEA
Biological Process
    axon guidance GO:0007411 TAS
    regulation of neuron migration GO:2001222 IEA
    regulation of establishment of cell polarity GO:2000114 IEA
Subcellular Localization
    axonal growth cone GO:0044295 IEA
 Experiment description of studies that identified KIAA1598 in exosomes
1
Experiment ID 211
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
EpCAM|TFRC
EV Membrane markers
cytochrome c|GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 212
ISEV standards
CEM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
EpCAM|TFRC
EV Membrane markers
Cytochrome C|GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for KIAA1598
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which KIAA1598 is involved
PathwayEvidenceSource
Recycling pathway of L1 TAS Reactome





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