Gene description for ZNF764
Gene name zinc finger protein 764
Gene symbol ZNF764
Other names/aliases -
Species Homo sapiens
 Database cross references - ZNF764
ExoCarta ExoCarta_92595
Vesiclepedia VP_92595
Entrez Gene 92595
HGNC 28200
UniProt Q96H86  
 ZNF764 identified in sEVs derived from the following tissue/cell type
Neuroblastoma cells 25944692    
 Gene ontology annotations for ZNF764
Molecular Function
    RNA polymerase II transcription regulatory region sequence-specific DNA binding GO:0000977 IBA
    DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 IBA
    transcription coregulator activity GO:0003712 IDA
    protein binding GO:0005515 IPI
    metal ion binding GO:0046872 IEA
Biological Process
    regulation of transcription by RNA polymerase II GO:0006357 IBA
    cellular response to glucocorticoid stimulus GO:0071385 IDA
Subcellular Localization
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IDA
 Experiment description of studies that identified ZNF764 in sEVs
1
Experiment ID 224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for ZNF764
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SUFU 51684
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
2 HOOK1  
Two-hybrid Homo sapiens
3 KPNA3 3839
Two-hybrid Homo sapiens
4 KRTAP2-3  
Two-hybrid Homo sapiens
5 SPERT  
Two-hybrid Homo sapiens
6 MDFI  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
7 TRIM33 51592
Affinity Capture-MS Homo sapiens
8 USP9X 8239
Affinity Capture-MS Homo sapiens
9 DVL3 1857
Two-hybrid Homo sapiens
10 ZNF92  
Affinity Capture-MS Homo sapiens
11 GNE 10020
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
12 ARMC7  
Two-hybrid Homo sapiens
13 KRTAP2-4  
Two-hybrid Homo sapiens
14 KRTAP4-12  
Two-hybrid Homo sapiens
15 TRIM28 10155
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
16 ZNF813  
Affinity Capture-MS Homo sapiens
17 ZNF408  
Two-hybrid Homo sapiens
18 LRRC1 55227
Affinity Capture-MS Homo sapiens
19 MRPS5 64969
Affinity Capture-MS Homo sapiens
20 LASP1 3927
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
21 RECQL4  
Affinity Capture-MS Homo sapiens
22 KRI1  
Affinity Capture-MS Homo sapiens
23 MTUS2 23281
Two-hybrid Homo sapiens
24 MRPS26 64949
Affinity Capture-MS Homo sapiens
25 HELZ2  
Affinity Capture-MS Homo sapiens
26 IPO8 10526
Affinity Capture-MS Homo sapiens
27 CAMK2B 816
Affinity Capture-MS Homo sapiens
28 OBSL1 23363
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
29 KRTAP4-4  
Two-hybrid Homo sapiens
30 GOLGA6L9  
Two-hybrid Homo sapiens
31 TRIM41 90933
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
32 CLK2 1196
Two-hybrid Homo sapiens
33 FHL5 9457
Two-hybrid Homo sapiens
34 PLSCR1 5359
Two-hybrid Homo sapiens
35 ZNF330  
Two-hybrid Homo sapiens
36 FBLN1 2192
Affinity Capture-MS Homo sapiens
37 TRIM24  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
38 CTC1  
Affinity Capture-MS Homo sapiens
39 CYSRT1 375791
Two-hybrid Homo sapiens
40 CBX5 23468
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
41 ZNF324  
Affinity Capture-MS Homo sapiens
42 GTF3C2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
43 PPP2CA 5515
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
44 CYP24A1  
Affinity Capture-MS Homo sapiens
45 S100B 6285
Affinity Capture-MS Homo sapiens
46 FBLN5 10516
Affinity Capture-MS Homo sapiens
47 KRTAP10-7  
Two-hybrid Homo sapiens
48 ZNF316  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
49 GTF3C3 9330
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
50 KRTAP1-3  
Two-hybrid Homo sapiens
51 CUL3 8452
Affinity Capture-MS Homo sapiens
52 SMARCAD1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
53 MRPS35 60488
Affinity Capture-MS Homo sapiens
54 ZNF837  
Two-hybrid Homo sapiens
55 TRAF7  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
56 ERBB2IP 55914
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
57 GTF3C1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
58 NEBL 10529
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
59 SNX18 112574
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
60 PPP1R37 284352
Two-hybrid Homo sapiens
61 LTBP4 8425
Affinity Capture-MS Homo sapiens
62 RPS27A 6233
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
63 GTF3C4 9329
Affinity Capture-MS Homo sapiens
64 CCDC85B  
Two-hybrid Homo sapiens
65 TRIM27  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
66 EHMT2 10919
Affinity Capture-MS Homo sapiens
67 TRIM39  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
68 CCDC125 202243
Two-hybrid Homo sapiens
69 MDM2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
70 VWCE  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
71 TRIM38 10475
Two-hybrid Homo sapiens
72 SH3PXD2B 285590
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
73 USP34 9736
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
74 MRPS31  
Affinity Capture-MS Homo sapiens
75 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
76 NISCH 11188
Affinity Capture-MS Homo sapiens
77 ZNF195  
Affinity Capture-MS Homo sapiens
78 KRTAP12-2  
Two-hybrid Homo sapiens
79 YTHDC2 64848
Affinity Capture-MS Homo sapiens
80 MYO1E 4643
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
81 HNRNPF 3185
Two-hybrid Homo sapiens
82 KRAS 3845
Synthetic Growth Defect Homo sapiens
83 SH3KBP1 30011
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
84 MRPS9 64965
Affinity Capture-MS Homo sapiens
85 KDM5C  
Affinity Capture-MS Homo sapiens
86 SH3PXD2A 9644
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
87 KRTAP10-9  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which ZNF764 is involved
PathwayEvidenceSource
Gene expression (Transcription) TAS Reactome
Generic Transcription Pathway TAS Reactome
RNA Polymerase II Transcription TAS Reactome





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