Gene description for FHL5
Gene name four and a half LIM domains 5
Gene symbol FHL5
Other names/aliases ACT
dJ393D12.2
Species Homo sapiens
 Database cross references - FHL5
ExoCarta ExoCarta_9457
Vesiclepedia VP_9457
Entrez Gene 9457
HGNC 17371
MIM 605126
UniProt Q5TD97  
 FHL5 identified in exosomes derived from the following tissue/cell type
Urine 21595033    
Urine 21595033    
Urine 21595033    
 Gene ontology annotations for FHL5
Molecular Function
    transcription coactivator activity GO:0003713 IBA
    protein binding GO:0005515 IPI
    metal ion binding GO:0046872 IEA
Biological Process
    positive regulation of transcription by RNA polymerase II GO:0045944 IBA
Subcellular Localization
    nucleus GO:0005634 IBA
    Z disc GO:0030018 IBA
 Experiment description of studies that identified FHL5 in exosomes
1
Experiment ID 193
MISEV standards
EM
Biophysical techniques
CD63|CD9
Enriched markers
PHB
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 194
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of basement membrane nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
3
Experiment ID 195
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of early IgA nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for FHL5
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 TUSC2  
Two-hybrid Homo sapiens
2 FHL5 9457
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
3 ZNF24  
Affinity Capture-MS Homo sapiens
4 ZNHIT1  
Two-hybrid Homo sapiens
5 COIL  
Two-hybrid Homo sapiens
6 AGXT  
Two-hybrid Homo sapiens
7 SCNM1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
8 CREM  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
9 PLEKHA2 59339
Two-hybrid Homo sapiens
10 HAPLN2  
Two-hybrid Homo sapiens
11 ZNF446  
Two-hybrid Homo sapiens
12 LMO2  
Two-hybrid Homo sapiens
13 HOXB9  
Two-hybrid Homo sapiens
14 ZBTB33  
Affinity Capture-MS Homo sapiens
15 HCK 3055
Two-hybrid Homo sapiens
16 ZNF408  
Two-hybrid Homo sapiens
17 ZNF440  
Two-hybrid Homo sapiens
18 PPP1R18 170954
Two-hybrid Homo sapiens
19 MAGOHB 55110
Two-hybrid Homo sapiens
20 CTSZ 1522
Two-hybrid Homo sapiens
21 CATSPER1  
Two-hybrid Homo sapiens
22 SDCBP 6386
Two-hybrid Homo sapiens
23 BCL6B  
Two-hybrid Homo sapiens
24 ZMYM1 79830
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
25 FAM154A  
Two-hybrid Homo sapiens
26 ADAM12 8038
Two-hybrid Homo sapiens
27 FARS2 10667
Two-hybrid Homo sapiens
28 BANP  
Two-hybrid Homo sapiens
29 DNAL4  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
30 RAB3IL1 5866
Two-hybrid Homo sapiens
31 ZNF124  
Two-hybrid Homo sapiens
32 FAM71C  
Two-hybrid Homo sapiens
33 ZNF613  
Two-hybrid Homo sapiens
34 MYOZ3  
Two-hybrid Homo sapiens
35 ZBTB16  
Two-hybrid Homo sapiens
36 HEY2  
Two-hybrid Homo sapiens
37 CFP  
Two-hybrid Homo sapiens
38 CNNM3 26505
Two-hybrid Homo sapiens
39 HDX  
Two-hybrid Homo sapiens
40 ZNF23  
Two-hybrid Homo sapiens
41 NPDC1  
Two-hybrid Homo sapiens
42 ZNF131  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
43 FEZF1  
Two-hybrid Homo sapiens
44 ZNF581  
Two-hybrid Homo sapiens
45 QRICH1  
Two-hybrid Homo sapiens
46 ZNF251  
Two-hybrid Homo sapiens
47 GPS2  
Two-hybrid Homo sapiens
48 BBC3  
Two-hybrid Homo sapiens
49 CTU1 90353
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
50 TAX1BP1 8887
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
51 ANKRD55  
Two-hybrid Homo sapiens
52 ZNF564  
Two-hybrid Homo sapiens
53 C19orf66  
Two-hybrid Homo sapiens
54 ZNF250  
Two-hybrid Homo sapiens
55 HOXA1 3198
Two-hybrid Homo sapiens
56 IL16  
Two-hybrid Homo sapiens
57 OTX1  
Two-hybrid Homo sapiens
58 Hoxa1  
Two-hybrid Mus musculus
PCA Mus musculus
Affinity Capture-Western Mus musculus
59 ZMYM6  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
60 CRYBA4  
Two-hybrid Homo sapiens
61 SEC31A 22872
Two-hybrid Homo sapiens
62 SPRY1 10252
Two-hybrid Homo sapiens
63 IP6K3  
Two-hybrid Homo sapiens
64 ZNF587  
Two-hybrid Homo sapiens
65 PPP1R32  
Two-hybrid Homo sapiens
66 LRRC41 10489
Two-hybrid Homo sapiens
67 CDC20B  
Two-hybrid Homo sapiens
68 ZNF417  
Two-hybrid Homo sapiens
69 SLIT1 6585
Two-hybrid Homo sapiens
70 PDLIM7 9260
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
71 DCDC2B  
Two-hybrid Homo sapiens
72 ADAMTSL5  
Two-hybrid Homo sapiens
73 CEP76  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
74 NEK6 10783
Two-hybrid Homo sapiens
75 PIN1 5300
Two-hybrid Homo sapiens
76 NUFIP2 57532
Two-hybrid Homo sapiens
77 RPS21 6227
Two-hybrid Homo sapiens
78 ZNF764 92595
Two-hybrid Homo sapiens
79 CREB1  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
80 ZNF792 126375
Two-hybrid Homo sapiens
81 ABI2 10152
Two-hybrid Homo sapiens
82 ZNF766  
Two-hybrid Homo sapiens
83 RAB26  
Two-hybrid Homo sapiens
84 CRYBA2  
Two-hybrid Homo sapiens
85 KIR2DL4  
Two-hybrid Homo sapiens
86 FAM214B  
Two-hybrid Homo sapiens
87 PLEKHN1  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which FHL5 is involved
No pathways found





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